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公开(公告)号：US20240094113A1
公开(公告)日：2024-03-21
申请号：US18262555
申请日：2021-11-01
发明人： Wei SHI , Xianghua SHI , Jianhua WANG , Linqun TANG
CPC分类号： G01N21/0303 , G01N21/05
摘要： The invention relates to a cuvette assembly for a sample processor, a flow cell for a sample processor comprising the cuvette assembly, and a sample processor comprising the cuvette assembly or the flow cell. The cuvette assembly comprises a cuvette body and a reflector. The cuvette body is in the shape of a rectangular parallelepiped and comprises a sample detection channel vertically penetrating the cuvette body. The cuvette body has long sides and short sides in a horizontal section. The reflector has a flat surface attached to a first side surface extending along one of the long sides of the cuvette body and a spherical surface that is opposite to the flat surface and has a truncated lower half. The reflector is positioned so that it is flush with a lower surface of the cuvette body and a center of sphere of the spherical surface falls into the sample detection channel, and the reflector extends along the long side and exceeds the short side.
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公开(公告)号：US20240085305A1
公开(公告)日：2024-03-14
申请号：US18262359
申请日：2021-12-28
发明人： Jeff DEGEAL , Robert BURR , John TYKSINSKI , Jingzhe ZHAO , Sheng YU , Xuewen QIAO
IPC分类号： G01N15/14
CPC分类号： G01N15/1427 , G01N15/147 , G01N2015/149 , G01N2015/1493
摘要： The present application discloses a system and a method for calculating a droplet delay time in a liquid flow of a sorting device, and a sorting device. The system includes: a first laser source configured to emit a first laser beam to a liquid flow of a sorting device, the first laser beam and the liquid flow intersecting at a first laser interrogation point located in a nozzle system of the sorting device; a second laser source configured to emit a second laser beam to the liquid flow, the second laser beam and the liquid flow intersecting at a second laser interrogation point located outside the nozzle system; a first detector and a second detector which are respectively used for detecting emission, in response to the first laser beam and the second laser beam, of a particle in the liquid flow; and a droplet delay time calculation unit configured to calculate, on the basis of the time when the particle in the liquid flow passes through the first laser interrogation point and the time when the particle passes through the second laser interrogation point, a first delay time for the liquid flow flowing from the first laser interrogation point to the second laser interrogation point, and calculate, on the basis of the first delay time, a droplet delay time.
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公开(公告)号：USD992751S1
公开(公告)日：2023-07-18
申请号：US29798144
申请日：2021-07-06
设计人： Xi Liu , Cheng Li , Jingzhang Wu
摘要： FIG. 1 is a top-front-right perspective view of a sample processing instrument, showing our new design, according to a first embodiment thereof;
FIG. 2 is a front elevation view thereof, according to the first embodiment thereof;
FIG. 3 is a rear elevation view thereof, according to the first embodiment thereof;
FIG. 4 is a left side elevation view thereof, according to the first embodiment thereof;
FIG. 5 is a right side elevation view thereof, according to the first embodiment thereof;
FIG. 6 is a top plan view thereof, according to the first embodiment thereof;
FIG. 7 is a bottom plan view thereof, according to the first embodiment thereof;
FIG. 8 is a top-front-right perspective view thereof, according to a second embodiment thereof;
FIG. 9 is a front elevation view thereof, according to the second embodiment thereof;
FIG. 10 is a rear elevation view thereof, according to the second embodiment thereof;
FIG. 11 is a left side elevation view thereof, according to the second embodiment thereof;
FIG. 12 is a right side elevation view thereof, according to the second embodiment thereof;
FIG. 13 is a top plan view thereof, according to the second embodiment thereof; and,
FIG. 14 is a bottom plan view thereof, according to the second embodiment thereof.
In FIGS. 8-14, different stippling patterns indicate different regions of contrasting appearance.-
公开(公告)号：US20230121733A1
公开(公告)日：2023-04-20
申请号：US17790955
申请日：2021-11-30
发明人： Linqun TANG , Simon NAVA , Juntao YUAN , Liang SHI
摘要： The present disclosure relates to a fluid system for a sample processor and a sample processor including the fluid system. The fluid system includes a sample line, a processing fluid line, a vacuum line, and an air pump. The sample line communicates a sample container with a sample port of a flow cell unit. The processing fluid line communicates a sheath fluid container with a processing fluid port of the flow cell unit. The vacuum line is in communication with the flow cell unit. The air pump includes a first output port and a second output port. Pressurized gas is generated at the first output port, and the first output port is in communication with the sample container and the sheath fluid container. A vacuum is generated at the second output port, and the second output port is in communication with a vacuum port of the flow cell unit through the vacuum line.
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公开(公告)号：US20240125592A1
公开(公告)日：2024-04-18
申请号：US18356674
申请日：2023-07-21
发明人： Wei SHI , Ruifeng MIAO , Zhonghui CHEN , Jianhua WANG
CPC分类号： G01B11/2433 , G01B11/26
摘要： The present disclosure relates to a beam measuring device, a sample processor including the beam measuring device, and a method of measuring a beam using the beam measuring device. The beam measuring device includes a detection unit and a light impediment unit. The light impediment unit is located between the detection unit and a light source, and is configured to generate a shadow area on the detection unit by blocking transmission of part of a beam coming from the light source. The detection unit is configured to measure the shadow area, and to determine whether the beam is divergent or inclined with respect to a predetermined optical axis based on the measurement of the shadow area. The beam measuring device may shorten the optical detection channel and ensure the detection accuracy, thereby having a compact structure. In addition, the beam measuring device may measure divergence angle and directionality, respectively.
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公开(公告)号：US20240110857A1
公开(公告)日：2024-04-04
申请号：US18262544
申请日：2021-11-01
发明人： Ruifeng MIAO , Wei SHI , Jingzhang WU
IPC分类号： G01N15/14
CPC分类号： G01N15/1404 , G01N15/149
摘要： The present disclosure relates to a liquid flow charging device for a flow cell and a flow cell comprising the liquid flow charging device. The liquid flow charging device comprises a first electrode and a second electrode. The first electrode is electrically connected to a liquid flow flowing through a flow channel assembly of the flow cell. The second electrode is located at a predetermined position on a radially outer side of the liquid flow and has a cylindrical inner peripheral surface surrounding the liquid flow. The liquid flow charging device has improved charging efficiency, stable charging performance, and enhanced safety.
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公开(公告)号：US12105008B2
公开(公告)日：2024-10-01
申请号：US17790955
申请日：2021-11-30
发明人： Linqun Tang , Simon Nava , Juntao Yuan , Liang Shi
IPC分类号： G01N15/1404 , B01L3/00 , G01N15/1409
CPC分类号： G01N15/1404 , B01L3/502 , B01L2200/146 , B01L2300/049 , B01L2300/14 , B01L2400/049 , B01L2400/0622 , G01N15/1409
摘要： The present disclosure relates to a fluid system for a sample processor and a sample processor including the fluid system. The fluid system includes a sample line, a processing fluid line, a vacuum line, and an air pump. The sample line communicates a sample container with a sample port of a flow cell unit. The processing fluid line communicates a sheath fluid container with a processing fluid port of the flow cell unit. The vacuum line is in communication with the flow cell unit. The air pump includes a first output port and a second output port. Pressurized gas is generated at the first output port, and the first output port is in communication with the sample container and the sheath fluid container. A vacuum is generated at the second output port, and the second output port is in communication with a vacuum port of the flow cell unit through the vacuum line.
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公开(公告)号：US20240118186A1
公开(公告)日：2024-04-11
申请号：US18485148
申请日：2023-10-11
发明人： Jianxiang DIAO , Xiaonan CAI
CPC分类号： G01N15/1429 , G01N21/64 , G01N2015/1402
摘要： The present application relates to a system or method for auto gating of QC base on population analysis. The system or method is particular useful for a sample processing instrument (for example, a flow cytometer or analyzer). The method comprise the following steps: I) providing QC beads used for testing the performance index of an equipment of interest; II) setting the equipment to collect the data of the QC beads; III) analyzing the collected data and calculating the gate position of QC beads based on the collected data; and VI) adjusting the acquisition parameters of the equipment based on the calculated gate position.
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公开(公告)号：US20240075477A1
公开(公告)日：2024-03-07
申请号：US18262559
申请日：2022-01-24
发明人： Wei SHI , Jingzhang WU , Erwin SCHOLZ
CPC分类号： B01L3/56 , B05B15/60 , B01L2200/025 , B01L2200/0689 , B01L2300/0609
摘要： The present disclosure relates to a nozzle for a sample processor, a carrier of a nozzle for a sample processor, a nozzle assembly for a sample processor, and a sample processor. The nozzle includes a body and an orifice. The body is adapted to be loaded and held in the carrier. The carrier can be slidably inserted into the sample processor in a detachable manner. The orifice is provided in the body and is configured to inject a sample from an injector body in a predetermined mode. An end surface of the body is adapted to abut against an end surface of the injector body along a sample injection direction. The nozzle assembly and the sample processor according to the present disclosure include the above-described nozzle and carrier. With the aid of the carrier, it is not necessary to install the nozzle to the injector body upstream of the nozzle, so that various adjustment operations when reinstalling the nozzle can be omitted, thereby simplifying the process of reinstalling the nozzle.
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公开(公告)号：US20240012220A1
公开(公告)日：2024-01-11
申请号：US18348250
申请日：2023-07-06
发明人： Jingzhang WU , Wenlei FANG , Jianhua WANG
CPC分类号： G02B7/023 , G01N15/1434 , G02B7/026 , G02B7/022 , G02B7/04 , G02B7/021 , G01N2015/1452
摘要： The present disclosure relates to a device for mounting an optical element and a sample processing instrument including the device for mounting an optical element. The device for mounting the optical element includes: a frame; a mount fitted in the frame in a translatable but non-rotatable manner and having a mounting portion for accommodating the optical element; and an adjusting nut attached to the frame in a rotatable but non-translatable manner. The adjusting nut has a screw and a head located at an end of the screw for operation, and the mount has a threaded portion engaged threadedly with the screw, such that when the adjusting nut rotates, the mount translates relative to the frame. The device and the sample processing instrument according to the disclosure can allow adjustment of an optical element while preventing the latter from being off-center.
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