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    Imide-free and mixed amide/imide thermal synthesis of polyaspartate
    2.
    发明授权
    Imide-free and mixed amide/imide thermal synthesis of polyaspartate 失效
    聚天冬氨酸的无酰胺和混合酰胺/酰亚胺热合成

    公开(公告)号：US5981691A

    公开(公告)日：1999-11-09

    申请号：US842016

    申请日：1997-04-23

    申请人： C. Steven Sikes

    发明人： C. Steven Sikes

    IPC分类号： C08G69/10 ,  C08G69/42 ,  C08G73/10

    CPC分类号： C08G73/1092 ,  C08G69/10

    摘要： Thermal polymerization of a salt of aspartic acid affords polyaspartate directly without hydrolyzing polysuccinimide. Copolymerization of a salt of aspartic acid with aspartic acid itself affords a copolymer of succinimide and aspartate which may be readily derivatized to produce a sulfonated, phosphonated or hydrophobized polymer.

    摘要翻译： 天冬氨酸盐的热聚合直接提供聚天冬氨酸，而不会水解聚琥珀酰亚胺。 天冬氨酸盐与天冬氨酸本身的共聚得到琥珀酰亚胺和天冬氨酸的共聚物，其可以容易地衍生化以产生磺化，膦酸化或疏水化的聚合物。

    Polyamino acid superabsorbents
    3.
    发明授权
    Polyamino acid superabsorbents 失效
    聚氨基酸超吸收剂

    公开(公告)号：US5284936A

    公开(公告)日：1994-02-08

    申请号：US870241

    申请日：1992-04-17

    申请人： Julie Donachy ,  C. Steven Sikes

    发明人： Julie Donachy ,  C. Steven Sikes

    IPC分类号： A61L15/00 ,  A61F13/53 ,  A61L15/60 ,  B01J20/22 ,  C07K2/00 ,  C07K14/00 ,  C08G69/10 ,  C08G73/10 ,  C09K3/00 ,  A61F13/15 ,  B01J20/26 ,  C07K15/00 ,  C08L77/04

    CPC分类号： C08G73/1092 ,  A61L15/60 ,  C07K14/001 ,  C08G69/10

    摘要： Substantially water-insoluble, crosslinked polypeptides containing 15 to 85 mole % of amino acid residues such as glutamic acid, aspartic acid, phosphoserine, phosphohomoserine, phosphotyrosine, phosphothreonine, phosphoasparagine, or phosphoglutamine, and 15 to 85 mole % of amino acid residues such as lysine, arginine, asparagine, glutamine, serine or tyrosine, in which the degree of crosslinking is sufficient to result in a substantially water-insoluble polypeptide with the ability to absorb a 1 wt. % aqueous NaCl solution in an amount of at least 20 times the weight of the polypeptide, are useful as superabsorbents in devices such as diapers, etc. Mild alkaline hydrolysis of the crosslinked polypeptides increases their superabsorbency by two to three fold.

    摘要翻译： 含有15〜85摩尔％的氨基酸残基例如谷氨酸，天冬氨酸，磷酸丝氨酸，磷酸高丝氨酸，磷酸酪氨酸，磷酸苏氨酸，磷酸磷酸谷氨酰胺或磷酸谷氨酰胺的基本上不溶于水的交联的多肽，以及15〜85摩尔％的氨基酸残基例如 赖氨酸，精氨酸，天冬酰胺，谷氨酰胺，丝氨酸或酪氨酸，其中交联度足以导致基本上不溶于水的多肽，其具有吸收1重量％ 数量为多肽重量的20倍的NaCl水溶液，可用作尿布等装置中的超吸收剂。交联的多肽的轻度碱性水解将其超吸收性增加2至3倍。

    Polyamino acid dispersants
    9.
    发明授权
    Polyamino acid dispersants 失效
    聚氨基酸分散剂

    公开(公告)号：US5328690A

    公开(公告)日：1994-07-12

    申请号：US658659

    申请日：1991-02-21

    申请人： C. Steven Sikes

    发明人： C. Steven Sikes

    IPC分类号： A61K47/42 ,  A61K8/04 ,  A61K8/64 ,  A61K8/88 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/10 ,  B01F17/30 ,  B01J13/00 ,  C08L101/00 ,  C09D5/00 ,  C09D17/00 ,  A61K7/06

    CPC分类号： A61K8/88 ,  A61K8/044 ,  A61Q19/10 ,  A61Q5/00 ,  A61Q5/02 ,  C09D17/004

    摘要： Polyamino acids of the formulae (I) and (II):poly (X).sub.n poly (Y).sub.m (I)whereeach X independently is aspartic acid, glutamic acid, phosphoserine, phosphohomoserine, phosphotyrosine, or phosphothreonine,each Y independently is alanine, leucine, isoleucine, valine, glycine or other nonpolar, amino acid residues,n is 2 to 60,m is 2 to 60, andn+m is .gtoreq.5,and whereinpoly (X).sub.n may contain up to 10% of the Y residues and poly (Y).sub.m may contain up to 10% of the X residues, and salts thereof; andpoly (X').sub.a poly (Y').sub.b (II)whereeach X' independently is aspartate, glutamate, glutamine, asparagine, or anionic derivatives of these amino acids, or phosphoserine,each Y' independently is a phosphorylated amino acid such as phosphoserine, phosphohomoserine, phosphotyrosine, phosphothreonine, phosphoglutamine, phosphoasparagine or mixtures of these residues,a is 2 to 150,b is 1 to 3, anda+b is .gtoreq.5, andsalts of these peptides;are effective as dispersing agents for minerals in aqueous media and for stabilizing aqueous suspensions of minerals.

    摘要翻译： 式（I）和（II）的聚氨基酸：聚（X）n聚（Y）m（I），其中每个X独立地是天冬氨酸，谷氨酸，磷酸丝氨酸，磷酸高丝氨酸，磷酸酪氨酸或磷酸苏氨酸， 丙氨酸，亮氨酸，异亮氨酸，缬氨酸，甘氨酸或其他非极性氨基酸残基，n为2至60，m为2至60，n + m为≥5，其中聚（X）n可含有 10％的Y残基和聚（Y）m可含有至多10％的X残基，及其盐; 和聚（X'）多聚（Y'）b（II），其中每个X'独立地是天冬氨酸，谷氨酸，谷氨酰胺，天冬酰胺或这些氨基酸的阴离子衍生物或磷酸丝氨酸，每个Y'独立地是磷酸化氨基酸 作为磷酸丝氨酸，磷酸高丝氨酸，磷酸酪氨酸，磷酸苏氨酸，磷酸谷氨酰胺，磷酸糖胺或这些残基的混合物，a为2〜150，b为1〜3，a + b为≥5， 作为矿物质在水介质中的分散剂和用于稳定矿物质的水悬浮液是有效的。

    Inhibition of inorganic and biological CaCO.sub.3 deposition by a polysaccharide fraction obtained from CaCO.sub.3 -forming organisms
    10.
    发明授权
    Inhibition of inorganic and biological CaCO.sub.3 deposition by a polysaccharide fraction obtained from CaCO.sub.3 -forming organisms 失效
    通过由CaCO 3形成的生物体获得的多糖部分抑制无机和生物CaCO 3沉积

    公开(公告)号：US4585560A

    公开(公告)日：1986-04-29

    申请号：US563252

    申请日：1983-12-19

    申请人： C. Steven Sikes ,  A. P. Wheeler

    发明人： C. Steven Sikes ,  A. P. Wheeler

    IPC分类号： C02F5/10

    CPC分类号： C02F5/10

    摘要： The present invention relates to a method of inhibiting the formation of CaCO.sub.3 -containing deposits on a surface, by applying a composition comprising an anti-calcification effective amount of the polysaccharide-containing fraction substantially devoid of proteinaceous material, isolated from a CaCO.sub.3 -containing tissue obtained from a CaCO.sub.3 -forming organism. The fractions can be isolated from a variety of CaCO.sub.3 -containing tissues, including but not limited to algae coccolith and the like. The present method is useful for the prevention and/or retardation of inorganic scaling, as well as, for the inhibition of fouling by plant or animal organisms.

    摘要翻译： 本发明涉及一种抑制含CaCO3沉积物在表面上形成的方法，该方法包括从含CaCO3的组织中分离出的包含抗钙化有效量的基本上不含蛋白质的多糖的级分的组合物 从形成CaCO3的生物获得。 可以从各种含CaCO 3的组织分离级分，包括但不限于藻类coccolith等。 本方法可用于防止和/或延缓无机鳞屑，以及用于抑制植物或动物生物体的结垢。