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公开(公告)号：US11832927B2
公开(公告)日：2023-12-05
申请号：US17501528
申请日：2021-10-14
IPC分类号： A61B5/0536 , A61B5/00 , A61B6/00 , A61B34/20 , A61B90/00 , G06T7/00 , A61B5/06 , A61B34/10 , A61B6/03 , G06T7/33 , G06T7/73 , A61B5/282
CPC分类号： A61B5/0536 , A61B5/0064 , A61B5/064 , A61B5/282 , A61B6/032 , A61B6/5247 , A61B34/20 , A61B90/361 , A61B90/39 , G06T7/0012 , G06T7/337 , G06T7/74 , A61B5/4836 , A61B5/684 , A61B5/6805 , A61B2034/105 , A61B2034/2051 , A61B2034/2065 , A61B2090/367 , A61B2090/376 , A61B2090/3937 , A61B2090/3966 , A61B2090/3983 , A61B2090/3995 , A61B2562/0209 , A61B2562/046 , G06T7/73 , G06T2207/10028 , G06T2207/10081 , G06T2207/30048 , G06T2207/30204
摘要： A method includes placing a set of electrodes on a body surface of a patient's body. The method also includes digitizing locations for the electrodes across the body surface based on one or more image frames using range imaging and/or monoscopic imaging. The method also includes estimating locations for hidden ones of the electrodes on the body surface not visible during the range imaging and/or monoscopic imaging. The method also includes registering the location for the electrodes on the body surface with predetermined geometry information that includes the body surface and an anatomical envelope within the patient's body. The method also includes storing geometry data in non-transitory memory based on the registration to define spatial relationships between the electrodes and the anatomical envelope.
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公开(公告)号：US20230321446A1
公开(公告)日：2023-10-12
申请号：US18318030
申请日：2023-05-16
发明人： William E. ROWLAND , Timothy G. LASKE , Qing LOU , Qingguo ZENG
CPC分类号： A61N1/365 , A61M60/178 , A61B5/367 , A61B5/287 , A61B5/063 , A61B5/4836 , A61B5/686 , A61N1/0563 , A61N1/37235 , A61B2560/0223
摘要： An example method includes establishing a communications link between an electrophysiology (EP) monitoring system and an implantable medical device (IMD). IMD electrical data is received at the monitoring system via the communications link. The IMD electrical data may be synchronized with EP measurement data to provide synchronized electrical data based on timing of a synchronization signal sensed by an IMD electrode and/or EP electrodes. The method also includes computing reconstructed electrical signals for locations on a surface of interest within the patient's body based on the synchronized electrical data and geometry data. The geometry data represents locations of the EP electrodes, a location of the IMD electrode within the patient's body and the surface of interest.
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公开(公告)号：US20230226361A1
公开(公告)日：2023-07-20
申请号：US18057454
申请日：2022-11-21
发明人： Qing LOU , Qingguo ZENG , TIMOTHY G. LASKE
CPC分类号： A61N1/36592 , A61B18/00 , A61M5/1723 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00839 , A61M2210/125 , A61M2230/04
摘要： A computer-implemented method includes accessing electrophysiological data and generating an electroanatomic map for a surface of interest based on the electrophysiological data acquired during or after application of a first intervention to temporarily perturb electrical properties of a region of interest on or within the patient’s heart. The method also includes determining changes in the map or information derived from the map responsive to application of a first intervention. The first intervention can include including applying a non-lethal energy and/or a bioactive agent to induce or inhibit conduction of electrical activity for the region of interest. The method also includes controlling a second intervention to permanently alter the electrical properties of the region of interest based on the determination indicating a desired change in cardiac electrical activity responsive to the first intervention.
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公开(公告)号：US11691018B2
公开(公告)日：2023-07-04
申请号：US17179465
申请日：2021-02-19
发明人： William Rowland , Timothy G. Laske , Qing Lou , Qingguo Zeng
CPC分类号： A61N1/365 , A61B5/063 , A61B5/287 , A61B5/367 , A61B5/4836 , A61B5/686 , A61M60/178 , A61N1/0563 , A61N1/37235 , A61B2560/0223
摘要： An example method includes establishing a communications link between an electrophysiology (EP) monitoring system and an implantable medical device (IMD). IMD electrical data is received at the monitoring system via the communications link. The IMD electrical data may be synchronized with EP measurement data to provide synchronized electrical data based on timing of a synchronization signal sensed by an IMD electrode and/or EP electrodes. The method also includes computing reconstructed electrical signals for locations on a surface of interest within the patient's body based on the synchronized electrical data and geometry data. The geometry data represents locations of the EP electrodes, a location of the IMD electrode within the patient's body and the surface of interest.
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公开(公告)号：US11576604B2
公开(公告)日：2023-02-14
申请号：US16870134
申请日：2020-05-08
IPC分类号： A61B5/00 , A61N1/362 , A61B5/02 , A61B5/316 , A61B5/11 , A61B5/318 , A61B5/349 , A61N1/368 , A61B5/283 , A61B5/287
摘要： Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.
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公开(公告)号：US20220104749A1
公开(公告)日：2022-04-07
申请号：US17553176
申请日：2021-12-16
发明人： PING JIA , QINGGUO ZENG , TIMOTHY G. LASKE , QING LOU
摘要： Systems and methods for cardiac fast firing (e.g., atrial fast firing) detection perform frequency analysis on channels of collected cardiac waveform data and test the data for outlier frequency complex content that is of higher frequency than baseline frequency complex content associated with cardiac fibrillation (e.g., atrial fibrillation) or other arrhythmogenic activity. Anatomical regions from whence the cardiac fast firing originates can be displayed in real time on an epicardial surface map via a graphical display, aiding administration of therapy. Prior to such detection, QRST complex removal can be performed to ensure that ventricular activity does not infect the atrial fast firing analysis. A frequency-based method for QRST complex removal is also disclosed.
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公开(公告)号：US11182911B2
公开(公告)日：2021-11-23
申请号：US16874298
申请日：2020-05-14
发明人： Glenn D. Raudins
IPC分类号： G06T7/20 , G06T7/292 , A61B5/06 , A61B5/00 , A61B8/00 , A61B8/08 , G06T7/12 , A61B5/282 , G06T7/62 , G06T7/10 , G06T7/30 , A61N1/18 , A61N1/00 , A61N1/05
摘要： Systems and methods can be used for ultrasound-based geometry determination for cardiac mapping. A patient can be scanned with an ultrasound while wearing body surface electrodes. While the scanning takes place, the location of the ultrasound transducer can be tracked in three-dimensional space. The electrodes can be tracked and located in the same coordinate system as the image volume. Therefore, each electrode's location can be determined relative to the acquired image volume such that corresponding geometry data is generated for the heart and the electrodes.
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公开(公告)号：US10713800B2
公开(公告)日：2020-07-14
申请号：US15991478
申请日：2018-05-29
发明人： Glenn D. Raudins
IPC分类号： G06T7/20 , G06T7/292 , A61B5/06 , A61B5/00 , A61B8/00 , A61B8/08 , A61B5/0408 , G06T7/12 , G06T7/62 , G06T7/10 , G06T7/30 , A61N1/18 , A61N1/00 , A61N1/05
摘要： Systems and methods can be used for ultrasound-based geometry determination for cardiac mapping. A patient can be scanned with an ultrasound while wearing body surface electrodes. While the scanning takes place, the location of the ultrasound transducer can be tracked in three-dimensional space. The electrodes can be tracked and located in the same coordinate system as the image volume. Therefore, each electrode's location can be determined relative to the acquired image volume such that corresponding geometry data is generated for the heart and the electrodes.
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公开(公告)号：US20200163570A1
公开(公告)日：2020-05-28
申请号：US16774662
申请日：2020-01-28
发明人： QING LOU , MEREDTH E. STONE , QINGGUO ZENG , JEFFREY B. ADAIR , CONNOR S. EDEL , PING JIA , KEVIN R. PONZIANI , BRIAN P. GEORGE , RYAN M. BOKAN , MATTHEW J. SABO , VLADIMIR A. TUROVSKIY , KETAL C. PATEL , CHARULATHA RAMANATHAN
IPC分类号： A61B5/0468 , A61B5/00 , A61B5/04 , A61B5/0408 , G16H50/30 , G16H40/63 , A61B5/0432 , A61B5/044 , A61B5/0472
摘要： An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.
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公开(公告)号：US20190336023A1
公开(公告)日：2019-11-07
申请号：US15971559
申请日：2018-05-04
发明人： QING LOU , JEFFREY B. ADAIR , QINGGUO ZENG , PING JIA , RYAN BOKAN , CONNOR EDEL , RAHSEAN ELLIS , BRIAN P. GEORGE , RAJA GHANEM , TIMOTHY G. LASKE
摘要： For example, one or more non-transitory computer-readable media includes executable instructions to perform a method. The method includes defining a plurality of spatial regions distributed across a geometric surface. At least one wave front that propagates across the geometric surface is detected based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval. An indication of conduction velocity of the wave front is determined for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region. Slow conduction activity is identified for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold. Conduction data is stored in memory to represent each slow conduction event.
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