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    Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline paraovirus and feline herpes virus
    1.
    发明申请
    Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline paraovirus and feline herpes virus 有权
    疫苗施用方法，新的猫科动物病毒和用于免疫动物抗猫病毒和猫疱疹病毒的治疗

    公开(公告)号：US20070031454A1

    公开(公告)日：2007-02-08

    申请号：US11494825

    申请日：2006-07-28

    申请人： David Lowery ,  Sing Rong ,  Paul Guimond ,  Paula Clare ,  Cassius Tucker ,  Thomas Newby

    发明人： David Lowery ,  Sing Rong ,  Paul Guimond ,  Paula Clare ,  Cassius Tucker ,  Thomas Newby

    IPC分类号： A61K39/125 ,  A61K48/00

    CPC分类号： C07K16/10 ,  A61K39/00 ,  A61K39/12 ,  A61K39/245 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/70 ,  C07K14/005 ,  C07K2317/76 ,  C12N7/00 ,  C12N2710/16734 ,  C12N2750/10034 ,  C12N2750/14334 ,  C12N2770/16021 ,  C12N2770/16022 ,  C12N2770/16034 ,  G01N33/56983 ,  G01N2469/10

    摘要： The present invention relates to a vaccine for immunizing a cat against feline viruses. The present invention also relates to a nucleic acid clone that encodes the capsid protein of the isolated feline calicivirus. The present invention further relates to a live or killed vaccine comprising the isolated feline calicivirus, a subunit vaccine comprising the capsid protein of the isolated feline calicivirus, a nucleic acid vaccine comprising a nucleic acid clone of the isolated feline calicivirus, and a recombinant virus vector vaccine comprising nucleic acid encoding the capsid protein of the isolated feline calicivirus. The present invention also relates to a method for identifying a feline calicivirus useful for producing a vaccine composition and for assays for diagnosing cats infected with feline calicivirus. Also disclosed is a method of immunizing animals, especially cats, against disease, in particular against feline calicivirus (FCV). The method includes administering to a cat therapeutically effective amounts of first and second FCV vaccines. The first vaccine is administered orally or parenterally (e.g., subcutaneously, intramuscularly, and the like). The second vaccine is administered orally or oronasally N days following administration of the first vaccine, wherein N is an integer from 3 to 120, inclusive. A third vaccine administration may also be given. The present invention also describes methods and materials for treating and immunizing animals with vaccine, and in particular cats against both FPV or Feline Parvovirus, which has also been called Panleukopenia or FPL and against another disease, FHV or Feline Herpes Virus, which has also been called Feline Rhinotracheitis Virus.

    摘要翻译： 本发明涉及用于免疫猫对猫科动物病毒的疫苗。 本发明还涉及编码分离的猫杯状病毒的衣壳蛋白的核酸克隆。 本发明还涉及包含分离的猫杯状病毒的活的或杀死的疫苗，包含分离的猫杯状病毒的衣壳蛋白的亚单位疫苗，包含分离的猫杯状病毒的核酸克隆的核酸疫苗和重组病毒载体 包含编码分离的猫杯状病毒的衣壳蛋白的核酸的疫苗。 本发明还涉及用于鉴定可用于产生疫苗组合物的猫杯状病毒病的方法和用于诊断感染猫杯状病毒的猫的测定方法。 还公开了免疫动物特别是猫的疾病，特别是针对猫杯状病毒（FCV）的方法。 该方法包括给予猫治疗有效量的第一和第二FCV疫苗。 第一种疫苗口服或肠胃外给药（例如皮下，肌肉内等）。 第二种疫苗在第一种疫苗给药后N天口服或鼻道给药，其中N为3至120的整数，包括端值在内。 也可以给予第三次疫苗管理。 本发明还描述了用疫苗治疗和免疫动物的方法和材料，特别是针对FPV或猫细小病毒的猫，其也称为泛素减少或FPL，并且与另一种疾病FHV或猫疱疹病毒 称为猫科鼻气管炎病毒。

    Canine vaccines against Bordetella bronchiseptica
    3.
    发明申请
    Canine vaccines against Bordetella bronchiseptica 审中-公开
    犬疫苗针对支气管炎博德特氏菌

    公开(公告)号：US20050089533A1

    公开(公告)日：2005-04-28

    申请号：US10959757

    申请日：2004-10-06

    申请人： Joseph Frantz ,  Cassius Tucker ,  Thomas Newby

    发明人： Joseph Frantz ,  Cassius Tucker ,  Thomas Newby

    IPC分类号： A61K39/02 ,  A61K39/10 ,  A61K39/12 ,  A61K39/155 ,  A61K39/175 ,  A61K39/23 ,  A61K39/235 ,  A61K39/295

    CPC分类号： A61K39/23 ,  A61K39/0225 ,  A61K39/099 ,  A61K39/12 ,  A61K39/155 ,  A61K39/175 ,  A61K39/215 ,  A61K39/235 ,  A61K39/39 ,  A61K2039/521 ,  A61K2039/5254 ,  A61K2039/545 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55505 ,  A61K2039/55511 ,  A61K2039/55577 ,  A61K2039/70 ,  C12N2710/10334 ,  C12N2710/20034 ,  C12N2750/14334 ,  C12N2760/18034 ,  C12N2760/18434

    摘要： This invention relates to vaccines and methods for protecting dogs against disease caused by Bordetella bronchiseptica. This invention relates to vaccines and methods for protecting dogs against disease caused by Leptospira bratislava. This invention also relates to combination vaccines and methods for protecting dogs against disease or disorder caused by canine pathogens, for example, infectious tracheobronchitis caused by Bordetella bronchiseptica, canine distemper caused by canine distemper (CD) virus, infectious canine hepatitis (ICH) caused by canine adenovirus type 1 (CAV-1), respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza (CPI) virus, enteritis caused by canine coronavirus (CCV) and canine parvovirus (CPV), and leptospirosis caused by Leptospira bratislava, Leptospira canicola, Leptospira grippotyphosa, Leptospira icterohaemorrhagiae or Leptospira pomona.

    摘要翻译： 本发明涉及用于保护狗免受由支气管炎博德特氏菌引起的疾病的疫苗和方法。 本发明涉及用于保护狗免于由钩端螺旋体梭菌引起的疾病的疫苗和方法。 本发明还涉及用于保护狗免受犬病原体引起的疾病或病症的组合疫苗和方法，例如由支气管炎博德特氏菌引起的感染性气管支气管炎，由犬瘟热（CD）病毒引起的犬瘟热，由...引起的感染性犬肝炎（ICH） 犬腺病毒1型（CAV-1），由犬腺病毒2型（CAV-2）引起的呼吸道疾病，犬副流感（CPI）病毒引起的副流感病毒，犬冠状病毒（CCV）和犬细小病毒（CPV）引起的肠炎， 由钩端螺旋体梭菌（Leptospira bratislava），钩端螺旋体钩端螺旋体（Leptospira canicola），钩端螺旋体夹柄菌（Leptospira grippotyphosa），十字螺旋体菌（Leptospira icterohaemorrhagia）或钩端螺旋体（Leptospira pomona））引起的钩端螺旋体病。