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公开(公告)号:US08529057B2
公开(公告)日:2013-09-10
申请号:US13193651
申请日:2011-07-29
申请人: Yongxing Qiu , Newton T. Samuel , John Dallas Pruitt , Chandana Kolluru , Arturo N. Medina , Lynn Cook Winterton , Daqing Wu , Xinming Qian , Jared Nelson
发明人: Yongxing Qiu , Newton T. Samuel , John Dallas Pruitt , Chandana Kolluru , Arturo N. Medina , Lynn Cook Winterton , Daqing Wu , Xinming Qian , Jared Nelson
IPC分类号: G02C7/00
CPC分类号: C09D177/06 , B29D11/00067 , C08G77/388 , C08J5/00 , C08J7/042 , C08J2383/04 , C08J2383/08 , C08J2433/02 , C08J2433/26 , C08J2487/00 , C08L83/04 , C09D5/1637 , C09D5/1681 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , G02B1/043 , G02B1/10 , G02B1/18 , G02C7/049 , G02C2202/06 , G02C2202/16 , C08L101/14
摘要: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.
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公开(公告)号:US20120026457A1
公开(公告)日:2012-02-02
申请号:US13193651
申请日:2011-07-29
申请人: Yongxing Qiu , Newton T. Samuel , John Dallas Pruitt , Chandana Kolluru , Arturo N. Medina , Lynn Cook Winterton , Daqing Wu , Xinming Qian , Jared Nelson
发明人: Yongxing Qiu , Newton T. Samuel , John Dallas Pruitt , Chandana Kolluru , Arturo N. Medina , Lynn Cook Winterton , Daqing Wu , Xinming Qian , Jared Nelson
CPC分类号: C09D177/06 , B29D11/00067 , C08G77/388 , C08J5/00 , C08J7/042 , C08J2383/04 , C08J2383/08 , C08J2433/02 , C08J2433/26 , C08J2487/00 , C08L83/04 , C09D5/1637 , C09D5/1681 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , G02B1/043 , G02B1/10 , G02B1/18 , G02C7/049 , G02C2202/06 , G02C2202/16 , C08L101/14
摘要: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.
摘要翻译: 本发明涉及制备其上具有交联亲水性涂层的硅氧水凝胶隐形眼镜的成本有效的方法。 本发明的方法涉及在具有带正电荷的氮杂环丁烷基团的水溶性,高度支化,热交联的亲水性聚合物材料存在下,在约40℃的温度下,在水溶液中加热硅酮水凝胶隐形眼镜 在约140℃下进行足够的时间以将可热交联的亲水聚合物材料共价连接到硅氧烷水凝胶隐形眼镜的表面上,通过共价连接,每个共价键在一个氮杂环丁烷基团和一个反应性官能团之间形成, 和/或靠近硅酮水凝胶隐形眼镜的表面,从而在硅氧水凝胶隐形眼镜上形成交联的亲水涂层。 这种方法可以有利地在高压釜中直接在密封的透镜包装中实现。
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公开(公告)号:US20120137635A1
公开(公告)日:2012-06-07
申请号:US13303186
申请日:2011-11-23
IPC分类号: B65B31/00
CPC分类号: B29D11/00038 , B29D11/00865
摘要: The invention provides a method of coating and thereby affecting the surface properties of a substrate such as a contact lens or other ophthalmic device. The method comprises the steps of generating an atmospheric plasma flow from a working gas and controlling the continuity of the atmospheric plasma flow with a power generator, and, introducing the atmospheric plasma flow to a substrate surface.
摘要翻译: 本发明提供一种涂覆方法,从而影响诸如隐形眼镜或其它眼科装置的基底的表面性质。 该方法包括以下步骤:从工作气体产生大气等离子体流,并用发电机控制大气等离子体流的连续性,以及将大气等离子体流引入衬底表面。
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公开(公告)号:US09156213B2
公开(公告)日:2015-10-13
申请号:US13303186
申请日:2011-11-23
IPC分类号: B29D11/00
CPC分类号: B29D11/00038 , B29D11/00865
摘要: The invention provides a method of coating and thereby affecting the surface properties of a substrate such as a contact lens or other ophthalmic device. The method comprises the steps of generating an atmospheric plasma flow from a working gas and controlling the continuity of the atmospheric plasma flow with a power generator, and, introducing the atmospheric plasma flow to a substrate surface.
摘要翻译: 本发明提供一种涂覆方法,从而影响诸如隐形眼镜或其它眼科装置的基底的表面性质。 该方法包括以下步骤:从工作气体产生大气等离子体流,并用发电机控制大气等离子体流的连续性,以及将大气等离子体流引入衬底表面。
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