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37 条记录 (耗时 0.013 秒)

    Dihydropyridine derivatives as stabilizers for vinyl chloride polymers
    1.
    发明授权
    Dihydropyridine derivatives as stabilizers for vinyl chloride polymers 失效
    二氢吡啶衍生物作为氯乙烯聚合物的稳定剂

    公开(公告)号：US4317768A

    公开(公告)日：1982-03-02

    申请号：US93861

    申请日：1979-11-13

    申请人： Charles Pigerol ,  Marie-Madeleine Chandavoine ,  Paul de Cointet de Fillain

    发明人： Charles Pigerol ,  Marie-Madeleine Chandavoine ,  Paul de Cointet de Fillain

    IPC分类号： C08K5/00 ,  C07D211/90 ,  C08K5/34 ,  C08K5/3412 ,  C08K5/3432 ,  C08L1/00 ,  C08L27/00

    CPC分类号： C08K5/3432 ,  C07D211/90 ,  C08K5/34

    摘要： The instant invention relates to compounds of the general formula: ##STR1## wherein R.sub.1 represents an alkyl, alkenyl, phenyl or phenylalkyl radical, R.sub.2 represents an alkyl, alkenyl or alkynyl radical, a .omega.-halogenoethyl radical, an optionally substituted benzyl radical, a phenylalkenyl radical, an optionally substituted phenyl radical, a radical of the formula R.sub.4 --O--(CH.sub.2).sub.n -- wherein n is 2, 3, or 4 and R.sub.4 represents an optionally substituted alkyl radical or a phenyl radical, R.sub.3 represents a hydrogen atom, an alkyl, alkenyl or phenyl radical.The compounds of formula I have been found to be useful as stabilizers for vinyl resins.

    摘要翻译： 本发明涉及以下通式的化合物：其中R 1表示烷基，烯基，苯基或苯基烷基，R 2表示烷基，烯基或炔基，ω-卤代乙基，任选取代的苄基， 苯基链烯基，任选取代的苯基，式R 4 -O-（CH 2）n - 的基团，其中n为2,3或4，R 4表示任选取代的烷基或苯基，R 3表示氢原子 ，烷基，烯基或苯基。 已经发现式I化合物可用作乙烯基树脂的稳定剂。

    Dihydropyridine derivatives
    2.
    发明授权
    Dihydropyridine derivatives 失效
    二氢吡啶衍生物

    公开(公告)号：US4239893A

    公开(公告)日：1980-12-16

    申请号：US96189

    申请日：1979-11-20

    申请人： Charles Pigerol ,  Marie-Madeleine Chandavoine ,  Paul de C. de Fillain

    发明人： Charles Pigerol ,  Marie-Madeleine Chandavoine ,  Paul de C. de Fillain

    IPC分类号： C08K5/00 ,  C07D211/90 ,  C08K5/34 ,  C08K5/3412 ,  C08K5/3432 ,  C08L1/00 ,  C08L27/00 ,  C07D213/55

    CPC分类号： C08K5/3432 ,  C07D211/90 ,  C08K5/34

    摘要： The instant invention relates to compounds of the general formula: ##STR1## wherein R.sub.1 represents an alkyl, alkenyl, phenylalkyl radical, R.sub.2 represents a straight-chain alkyl, a straight- or branched-chain alkenyl or alkynyl radical, a .omega.-halogenoethyl radical, an optionally substituted benzyl radical, or a radical of the formula R.sub.4 --O--(CH.sub.2).sub.n --wherein n is 2, 3 or 4 and R.sub.4 represents a substituted alkyl radical.The compounds of the foregoing formula have been found to be useful as stabilizers for vinyl resins.

    摘要翻译： 本发明涉及以下通式的化合物：其中R 1表示烷基，烯基，苯基烷基，R 2表示直链烷基，直链或支链烯基或炔基，ω-卤代乙基 ，任选取代的苄基或式R 4 -O-（CH 2）n - 的基团，其中n为2,3或4，并且R 4表示取代的烷基。 已经发现上述式的化合物可用作乙烯基树脂的稳定剂。

    Indole derivatives and process for preparing the same
    4.
    发明授权
    Indole derivatives and process for preparing the same 失效
    吲哚衍生物及其制备方法

    公开(公告)号：US4139634A

    公开(公告)日：1979-02-13

    申请号：US798802

    申请日：1977-05-20

    申请人： Charles Pigerol ,  Paul DE Cointet de Fillain ,  Pierre Eymard ,  Jean-Pierre Werbenec ,  Madeleine Broll

    发明人： Charles Pigerol ,  Paul DE Cointet de Fillain ,  Pierre Eymard ,  Jean-Pierre Werbenec ,  Madeleine Broll

    IPC分类号： A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D209/08 ,  C07D209/12 ,  C07D209/30 ,  C07D401/06

    CPC分类号： C07D209/12 ,  C07D209/08 ,  C07D209/30

    摘要： Indole derivatives of the formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl radical, R.sub.2 and R.sub.3, which are the same or different, each represent a hydrogen atom, a methyl or ethyl radical, a benzyl radical or represent together a pentamethylene, hexamethylene, oxydiethylene or N-methylaminodiethylene chain, forming thus a cycle with the nitrogen atom, R.sub.4 represents a phenyl, 2', 4'-dimethyl-phenyl, isopropyl, cyclopropyl, 1-methyl-cyclopropyl, cyclopentyl or cyclohexyl radical, R.sub.5 represents a hydrogen atom, a branched- or straight-chain alkyl radical containing from 1 to 3 carbon atoms, a methylthio or ethylthio radical or a straight-chain acyl radical containing from 2 to 6 carbon atoms, R.sub.6 represents a hydrogen atom or a halogen atom, a methyl, methoxy, hydroxy, carboxy, nitro, amino, methylamino or dimethylamino radical, R.sub.7 represents a hydrogen atom or a halogen atom and n is 1 or 2, with the proviso that two at least of the groups R.sub.5, R.sub.6 and R.sub.7 represent a hydrogen atom and that, when n is 2, one at least of the groups R.sub.2 and R.sub.3 is not a hydrogen atom, and their pharmaceutically acceptable acid addition salts.The derivatives of the invention are useful as antidepressant and/or antiaggressive agents.

    摘要翻译： 下式的吲哚衍生物：其中R 1表示氢原子或甲基，R 2和R 3相同或不同，各自表示氢原子，甲基或乙基，苄基或一起代表 五亚甲基，六亚甲基，氧联二乙烯或N-甲基氨基二亚乙基链，由此形成与氮原子的循环，R4代表苯基，2'，4'-二甲基 - 苯基，异丙基，环丙基，1-甲基 - 环丙基，环戊基或环己基 R 5表示氢原子，含有1〜3个碳原子的支链或直链烷基，甲硫基或乙硫基或含有2-6个碳原子的直链酰基，R6表示氢原子或 卤素原子，甲基，甲氧基，羟基，羧基，硝基，氨基，甲基氨基或二甲基氨基，R7表示氢原子或卤素原子，n为1或2，条件是两个至少R5， R6和R7表示氢 并且当n为2时，基团R 2和R 3中的至少一个不是氢原子，以及它们的药学上可接受的酸加成盐。

    Associations for stabilizing vinyl resins
    6.
    发明授权
    Associations for stabilizing vinyl resins 失效
    稳定乙烯基树脂的协会

    公开(公告)号：US4388430A

    公开(公告)日：1983-06-14

    申请号：US307298

    申请日：1981-09-30

    申请人： Paul de Cointet de Fillain ,  Charles Pigerol

    发明人： Paul de Cointet de Fillain ,  Charles Pigerol

    IPC分类号： C08K5/3432 ,  C08K5/17 ,  C08K5/34 ,  C09K15/20 ,  C09K15/30

    CPC分类号： C08K5/3432

    摘要： The invention relates to a combination of derivatives of dihydropyridine and .beta.-aminocrotonic acid derivatives intended for the stabilization of vinyl resins. The combination of a dihydropyridine derivative and a .beta.-aminocrotonic derivative gives rise to synergism of the stabilizing powers of each of those products.

    摘要翻译： 本发明涉及旨在稳定乙烯基树脂的二氢吡啶衍生物和β-氨基巴豆酸衍生物的组合。 二氢吡啶衍生物和β-氨基巴豆酸衍生物的组合产生了这些产物中每种产物的稳定化功能的协同作用。

    Active derivatives of methylamine in therapeutic compositions and methods of use
    9.
    发明授权
    Active derivatives of methylamine in therapeutic compositions and methods of use 失效
    治疗组合物和使用方法中甲胺的活性衍生物

    公开(公告)号：US4057644A

    公开(公告)日：1977-11-08

    申请号：US707897

    申请日：1976-07-22

    申请人： Charles Pigerol ,  Pierre Eymard ,  Jean-Claude Vernieres ,  Jean-Pierre Werbenec ,  Madeleine Broll

    发明人： Charles Pigerol ,  Pierre Eymard ,  Jean-Claude Vernieres ,  Jean-Pierre Werbenec ,  Madeleine Broll

    IPC分类号： A61K31/13 ,  A61K31/395 ,  A61K31/535 ,  C07D203/08 ,  C07D205/04 ,  C07D295/15

    CPC分类号： C07D203/08 ,  A61K31/13 ,  A61K31/395 ,  A61K31/535 ,  C07D205/04 ,  C07D295/15

    摘要： Methylamine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.3 each represent a hydrogen atom or a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 6 carbon atoms, R.sub.2 represents a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 2 to 7 carbon atoms with the proviso that when R.sub.2 represents an alkenyl radical of the formula CH.dbd.CH--R.sub.6 or an alkynyl radical of the formula C.tbd.C--R.sub.6, in which R.sub.6 represents a hydrogen atom or a straight- or branched-chain alkyl radical of 1 to 5 carbon atoms, R.sub.1 and R.sub.3 each represent an atom of hydrogen or an alkyl radical, R.sub.4 and R.sub.5, which are the same or different, each represent a hydrogen atom, a straight- or branched-chain alkyl, alkenyl or alkynyl radical containing from 1 to 5 carbon atoms or an .omega.-hydroxyalkyl radical containing from 2 to 5 carbon atoms or R.sub.4 and R.sub.5, when they are taken together represent an alkylene radical containing from 2 to 6 carbon atoms, an alkylidene radical containing from 1 to 5 carbon atoms or the radical --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --CH.sub.2 --, R.sub.1, R.sub.2 and R.sub.3 being such that the trisubstituted methylamine radical possesses no more than 13 carbon atoms.They are useful for treating Parkinson's disease and for correcting extra-pyramidal disturbances provoked by neuroleptics.

    摘要翻译： 下式的甲胺衍生物及其药学上可接受的酸加成盐，其中R 1和R 3各自表示氢原子或含有1至6个碳原子的直链或支链烷基，烯基或炔基，R 2表示 含有2至7个碳原子的直链或支链烷基，烯基或炔基，条件是当R 2表示式CH = CH-R 6的烯基或式C的炔基时， ，其中R 6表示氢原子或1至5个碳原子的直链或支链烷基，R 1和R 3各自表示氢或烷基的原子，R 4和R 5相同或不同， 各自表示氢原子，含有1至5个碳原子的直链或支链烷基，烯基或炔基或含有2至5个碳原子的ω-羟基烷基或R 4和R 5，当它们一起表示时 亚烷基 含有2至6个碳原子的二烷基，含有1至5个碳原子的亚烷基或基团-CH 2 -CH 2 -O-CH 2 -CH 2 - ，R 1，R 2和R 3使得三取代的甲基胺基不超过 13个碳原子。