Elastomeric, Polymeric Bone Engineering and Regeneration Compositions and Methods of Making
    3.
    发明申请
    Elastomeric, Polymeric Bone Engineering and Regeneration Compositions and Methods of Making 审中-公开
    弹性体,聚合骨工程和再生组合物和制备方法

    公开(公告)号:US20120143347A1

    公开(公告)日:2012-06-07

    申请号:US13310033

    申请日:2011-12-02

    IPC分类号: A61F2/28

    摘要: The invention relates to elastomeric, polymeric bone substitute compositions, methods for their preparation and their use in clinical applications, such as bone engineering and regeneration applications. The bone substitute compositions are osteoconductive in the absence of a biomolecule component. The bone substitute compositions are capable to regenerate bone in vitro or in vivo. The bone substitute compositions can be implanted into a bone defective site of a patient, and particularly, in the orthopedic, dental and caraniofacial areas of the patient.

    摘要翻译: 本发明涉及弹性体,聚合物骨替代组合物,其制备方法及其在临床应用中的应用,例如骨工程和再生应用。 在不存在生物分子组分的情况下,骨替代组合物是骨传导的。 骨替代组合物能够在体外或体内再生骨。 骨替代组合物可以植入患者的骨缺损部位,特别是在患者的整形外科,牙科和致癌区域中。

    Method of inducing biomineralization method of inducing bone regeneration and methods related thereof
    5.
    发明申请
    Method of inducing biomineralization method of inducing bone regeneration and methods related thereof 审中-公开
    诱导骨再生的生物矿化方法及其相关方法

    公开(公告)号:US20070087959A1

    公开(公告)日:2007-04-19

    申请号:US10568998

    申请日:2004-08-19

    IPC分类号: A61K38/17 A61K48/00 C07K14/47

    摘要: A method of inducing biomineralization in a tissue, which method comprises administering to the tissue a source of Phosphophoryn (PP) in an amount sufficient to induce biomineralization; a method of treating tooth sensitivity or injured pulp tissue; a method of inducing differentiation of a cell into an osteogenic cell or odontogenic cell; a method of inducing bone or dentin regeneration; a method of inducing periodontal regeneration; a method of inducing differentiation of a cell into a cementoblast, osteoblast, or periodontal ligament cell; and a composition comprising a source of PP and a carrier.

    摘要翻译: 一种在组织中诱导生物矿化的方法,该方法包括以足以诱导生物矿化的量向组织施用磷光源(PP)源; 治疗牙齿敏感性或损伤的纸浆组织的方法; 诱导细胞分化成成骨细胞或牙源性细胞的方法; 诱导骨或牙本质再生的方法; 一种诱导牙周再生的方法; 诱导细胞分化成成骨细胞,成骨细胞或牙周韧带细胞的方法; 以及包含PP源和载体的组合物。