公开(公告)号：US20090287077A1

公开(公告)日：2009-11-19

申请号：US12388694

申请日：2009-02-19

Applicant: Linda Chia-Hui Yu ,  Jong-Kai Hsiao

Inventor： Linda Chia-Hui Yu ,  Jong-Kai Hsiao

IPC: A61B5/055 ,  A61K49/00 ,  C12Q1/02 ,  A61B6/00

CPC classification number: A61B5/055 ,  A61B5/0515 ,  A61B5/412 ,  A61B5/4255 ,  A61K49/0004 ,  A61K49/06

Abstract: A system for detecting function of an intestinal barrier in a subject is provided, which includes: a contrast agent for being administered directly to an intestinal lumen of the subject, allowing a detecting device to detect in vivo or in vitro the signal indication produced by the contrast agent in the tested targets such as abdominal organs or a blood sample; and a determining device for determining intensity of the signal indication produced by the contrast agent in the tested targets after the administration of the contrast agent so as for the intensity of the signal indication after the administration of the contrast agent to indicate damage of the intestinal barrier in the subject. The present invention also provides a method of detecting function of the intestinal barrier in a subject by using the system of the present invention.

Abstract translation: 提供了一种用于检测受试者肠道屏障功能的系统，其包括：对象剂，其直接施用于受试者的肠腔，允许检测装置在体内或体外检测由所述受试者产生的信号指示 测试对象如腹部器官或血液样本中的造影剂; 以及确定装置，用于在施用造影剂之后确定由造影剂施用之后的测试目标中的造影剂产生的信号指示的强度，以便在施用造影剂之后信号指示的强度指示肠屏障的损伤 在主题。 本发明还提供了通过使用本发明的系统来检测受试者中肠屏障的功能的方法。

公开(公告)号：US20130021543A1

公开(公告)日：2013-01-24

申请号：US13546116

申请日：2012-07-11

Applicant: Chih-Hung LIN ,  Chia-Hui YU

Inventor： Chih-Hung LIN ,  Chia-Hui YU

IPC: C08L47/00 ,  G02F1/1333 ,  C08F236/20

CPC classification number: C08F236/20 ,  G03F7/027 ,  G03F7/0388

Abstract: A photosensitive resin composition includes: a copolymer obtained by subjecting a conjugated diene polymer having a (meth)acryloyl group, a conjugated diene monomer, and a (meth)acrylic acid monomer to copolymerization; a compound having at least one ethylenically unsaturated group; and a photoinitiator. The copolymer contains 60 wt % to 99 wt % of a copolymer fraction having a molecular weight ranging from 30,000 to 900,000, and 1 wt % to 22 wt % of a copolymer fraction having a molecular weight ranging from 1,000 to 10,000 when calculated from an integral molecular weight distribution curve obtained by plotting cumulative weight percentage versus molecular weight falling within a range between 1,000 and 1,000,000 measured by gel permeation chromatography.

Abstract translation: 感光性树脂组合物包括：使具有（甲基）丙烯酰基的共轭二烯聚合物，共轭二烯单体和（甲基）丙烯酸单体）共聚得到的共聚物; 具有至少一个烯属不饱和基团的化合物; 和光引发剂。 该共聚物含有60重量％至99重量％的分子量范围为30,000至900,000的共聚物部分和1重量％至22重量％的分子量为1,000至10,000的共聚物部分， 通过凝胶渗透色谱法测定的累积重量百分比与分子量在1,000和1,000,000之间的范围内所得到的分子量分布曲线。

公开(公告)号：US11505529B2

公开(公告)日：2022-11-22

申请号：US16490070

申请日：2018-03-02

Applicant: Linda Chia-Hui Yu

Inventor： Ling-Wei Hsin ,  Linda Chia-Hui Yu ,  Tsung-Chun Lee

IPC: C07D217/04 ,  A61P1/00 ,  C07D401/06

Abstract: A series of 8-phenyl-isoquinoline derivatives (I) exhibit high binding affinity to 5-HT7 receptor (5-HT7R) and demonstrate potent antinociceptive activity in two animal models for Irritable Bowel Syndrome (IBS) by intraperitoneal injection (i.p.) or by oral administration (p.o.). These 5-HT7 receptor antagonists are a new class of therapeutic agents for the treatment of IBS.

公开(公告)号：US20120002138A1

公开(公告)日：2012-01-05

申请号：US13067763

申请日：2011-06-24

Applicant: Chih-Hung Lin ,  Chia Hui Yu

Inventor： Chih-Hung Lin ,  Chia Hui Yu

IPC: G02F1/13357 ,  F21V7/22 ,  G02B6/26 ,  C09D11/10

CPC classification number: C09D11/106 ,  C09D11/101 ,  G02B6/0043 ,  G02B6/0065

Abstract: The present invention relates to a pattern forming ink composition, and more particularly, to a pattern forming ink composition having high yellowing resistance, wherein the pattern forming ink composition including an acrylate-based resin having a ring structure (A), a compound having at least one ethylenically unsaturated double bond (B) and a photoinitiator (C). The pattern forming ink is printed as a reflection pattern on a light guide plate to scatter and reflect the light incident to the reflection pattern towards a light emitting surface of the light guide plate.

Abstract translation: 本发明涉及图案形成油墨组合物，更具体地说，涉及具有高耐黄变性的图案形成油墨组合物，其中，图案形成油墨组合物包括具有环结构（A）的丙烯酸酯类树脂，具有 至少一个烯属不饱和双键（B）和光引发剂（C）。 图案形成油墨作为反射图案印刷在导光板上，以将入射到反射图案的光朝向导光板的发光表面散射并反射。

公开(公告)号：US20130012669A1

公开(公告)日：2013-01-10

申请号：US13529106

申请日：2012-06-21

Applicant: Chih-Hung LIN ,  Chia-Hui Yu

Inventor： Chih-Hung LIN ,  Chia-Hui Yu

IPC: C09J163/02 ,  B32B37/12

CPC classification number: C08K5/5435 ,  C08K3/36 ,  C08K5/0025 ,  C08K5/17 ,  C08L63/00

Abstract: A thermosetting resin composition includes an epoxy resin, a polyetheramine curing agent, and an epoxy silane coupling agent. The polyetheramine curing agent is in an amount less than or equal to 10 parts by weight and the epoxy silane coupling agent is in an amount more than or equal to 10 parts by weight based on 100 parts by weight of the epoxy resin.

Abstract translation: 热固性树脂组合物包括环氧树脂，聚醚胺固化剂和环氧硅烷偶联剂。 聚醚胺固化剂的量小于或等于10重量份，环氧硅烷偶联剂的用量大于或等于10重量份，基于100重量份的环氧树脂。

公开(公告)号：US20200071274A1

公开(公告)日：2020-03-05

申请号：US16490070

申请日：2018-03-02

Applicant: Linda Chia-Hui Yu

Inventor： Ling-Wei Hsin ,  Linda Chia-Hui Yu ,  Tsung-Chun Lee

IPC: C07D217/04 ,  C07D401/06 ,  A61P1/00

Abstract: A series of 8-phenyl-isoquinoline derivatives (I) exhibit high binding affinity to 5-HT7 receptor (5-HT7R) and demonstrate potent antinociceptive activity in two animal models for Irritable Bowel Syndrome (IBS) by intraperitoneal injection (i.p.) or by oral administration (p.o.). These 5-HT7 receptor antagonists are a new class of therapeutic agents for the treatment of IBS.