Enhanced sequencing by hybridization using pools of probes
    6.
    发明授权
    Enhanced sequencing by hybridization using pools of probes 失效
    通过使用探针池的杂交进行增强的测序

    公开(公告)号:US08034566B2

    公开(公告)日:2011-10-11

    申请号:US11929233

    申请日:2007-10-30

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6874 C12Q2537/165

    摘要: The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.

    摘要翻译: 本发明提供了通过杂交(SBH)进行测序的方法,所述探针池通过减少鉴定靶核酸序列中的每个特定核苷酸所需的杂交信号的单独测量的数量,从而能够更高效地传导SBH。 本发明还提供了一组探针池和一组探测池的生成方法。

    Enhanced Sequencing by Hybridization Using Pools of Probes
    7.
    发明申请
    Enhanced Sequencing by Hybridization Using Pools of Probes 审中-公开
    通过使用探针池进行杂交的增强测序

    公开(公告)号:US20110039731A1

    公开(公告)日:2011-02-17

    申请号:US12644860

    申请日:2009-12-22

    IPC分类号: C40B40/06

    CPC分类号: C12Q1/6874 C12Q2537/165

    摘要: The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and set of pools of probes, as well as method of generating pools of probes.

    摘要翻译: 本发明提供了通过杂交(SBH)进行测序的方法,所述探针池通过减少鉴定靶核酸序列中的每个特定核苷酸所需的杂交信号的单独测量的数量,从而能够更高效地传导SBH。 本发明还提供了池和一组探测池,以及生成探针池的方法。