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1.发明申请Methods of Therapy and Diagnosis Using Immunotargeting of CD84Hy1-expressing Cells 审中-公开使用CD84Hy1表达细胞免疫靶向治疗和诊断的方法公开(公告)号：US20090053136A1
公开(公告)日：2009-02-26
申请号：US12099621
申请日：2008-04-08
申请人： Douglas Dedera , Jian-Rui Wang , Peter C.R. Emtage
发明人： Douglas Dedera , Jian-Rui Wang , Peter C.R. Emtage
IPC分类号： A61K51/00 , A61K39/395 , A61K39/00 , A61K35/12 , A61K31/7088 , C12Q1/02 , C12Q1/68 , C07K16/18 , A61P31/00
CPC分类号： C07K14/70503 , A61K38/00 , A61K2039/505 , C07K14/70596 , C07K14/715 , C07K16/00 , C07K16/18 , C07K16/28 , C07K16/2896 , C07K16/3061 , C07K16/38 , C07K2317/77 , C12N9/16 , C12N9/6432 , C12Y304/21006 , G01N33/57492
摘要： Certain cells, including types of cancer cells such as lymphomas, are capable of expressing high levels of CD84Hy1. Immunotargeting using CD84Hy1 polypeptides, nucleic acids encoding for CD84Hy1 polypeptides and anti-CD84Hy1 antibodies provides a method of killing or inhibiting that growth of CD84HY1 Protein-expressing cancer cells. Methods of immunotherapy and diagnosis of disorders associated with CD84Hy1 protein-expressing cells are described.
摘要翻译： 某些细胞，包括淋巴瘤等癌细胞的类型能够表达高水平的CD84Hy1。 使用CD84Hy1多肽的免疫靶向，编码CD84Hy1多肽的核酸和抗CD84Hy1抗体提供了杀死或抑制表达CD84HY1蛋白的癌细胞生长的方法。 描述了与CD84Hy1蛋白表达细胞相关的病症的免疫治疗和诊断方法。
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2.发明申请Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides 审中-公开与CD84样多肽和多核苷酸相关的方法和材料公开(公告)号：US20090042199A1
公开(公告)日：2009-02-12
申请号：US12100713
申请日：2008-04-10
申请人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
发明人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
CPC分类号： C12N9/6432 , A61K38/00 , C07K14/70503 , C07K14/70596 , C07K14/715 , C07K16/00 , C12N9/16 , C12Y304/21006
摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译： 本发明提供由对应于新的人分泌的CD84样多肽的这种多核苷酸及其突变体或变体编码的新的多核苷酸和多肽。 这些多核苷酸包含从人脾cDNA文库中分离的核酸序列（Hyseq克隆鉴定号2938352（SEQ ID NO：1））。 本发明的其它方面包括含有生产新的人分泌的CD84样多肽的方法的载体和对这些多肽特异的抗体。
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公开(公告)号：US20050202422A1
公开(公告)日：2005-09-15
申请号：US10291128
申请日：2002-11-08
申请人： Y. Tang , Chenghua Liu , Vinod Asundi , Rui-Hong Chen , Feiyan Ren , Dunrui Wang , Jian-Rui Wang , Chongjun Xu , Aidong Xue , Yonghong Yang , Jie Zhang , Qing Zhao , Ping Zhou , Ryle Goodrich , Radoje Drmanac
发明人： Y. Tang , Chenghua Liu , Vinod Asundi , Rui-Hong Chen , Feiyan Ren , Dunrui Wang , Jian-Rui Wang , Chongjun Xu , Aidong Xue , Yonghong Yang , Jie Zhang , Qing Zhao , Ping Zhou , Ryle Goodrich , Radoje Drmanac
CPC分类号： C07K14/8107 , A61K38/00
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
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公开(公告)号：US20050175607A1
公开(公告)日：2005-08-11
申请号：US10220335
申请日：2001-02-26
申请人： Y Tang , Chenghua Liu , Vinod Asundi , Chongjun Xu , Tom Wehrman , Feiyan Ren , Yunqing Ma , Ping Zhou , Qing Zha , Yonghong Yang , Radoje Drmanac , Jie Zhang , Rui-hong Chen , Jian-Rui Wang , Dunrui Wang , Aidong Xue
发明人： Y Tang , Chenghua Liu , Vinod Asundi , Chongjun Xu , Tom Wehrman , Feiyan Ren , Yunqing Ma , Ping Zhou , Qing Zha , Yonghong Yang , Radoje Drmanac , Jie Zhang , Rui-hong Chen , Jian-Rui Wang , Dunrui Wang , Aidong Xue
CPC分类号： C07K14/47 , C12Q1/6886
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
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5.发明申请Methods and Materials Relating to CD84-like Polypeptides and Polynucelotides 有权与CD84样多肽和多聚核糖核酸相关的方法和材料公开(公告)号：US20090023659A1
公开(公告)日：2009-01-22
申请号：US12195282
申请日：2008-08-20
申请人： Chiaoyun Kuo , Bryan J. Boyle , Jian Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
发明人： Chiaoyun Kuo , Bryan J. Boyle , Jian Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
IPC分类号： A61K38/17 , G01N33/53 , C12P21/02 , A61K31/7088 , C12Q1/68
CPC分类号： C12N9/6432 , A61K38/00 , C07K14/70503 , C07K14/70596 , C07K14/715 , C07K16/00 , C12N9/16 , C12Y304/21006
摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译： 本发明提供由对应于新的人分泌的CD84样多肽的这种多核苷酸及其突变体或变体编码的新的多核苷酸和多肽。 这些多核苷酸包含从人脾cDNA文库中分离的核酸序列（Hyseq克隆鉴定号2938352（SEQ ID NO：1））。 本发明的其它方面包括含有生产新的人分泌的CD84样多肽的方法的载体和对这些多肽特异的抗体。
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6.发明申请METHODS AND MATERIALS RELATING TO CD84-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES 审中-公开与CD84-样多肽和多核苷酸相关的方法和材料公开(公告)号：US20110268724A1
公开(公告)日：2011-11-03
申请号：US13179183
申请日：2011-07-08
申请人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
发明人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
IPC分类号： A61K39/395 , C12P21/02 , A61K31/7088 , A61P35/00 , A61P37/06 , A61P29/00 , A61P17/06 , A61P1/00 , G01N33/53 , A61P31/12
CPC分类号： C12N9/6432 , A61K38/00 , C07K14/70503 , C07K14/70596 , C07K14/715 , C07K16/00 , C12N9/16 , C12Y304/21006
摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译： 本发明提供由对应于新的人分泌的CD84样多肽的这种多核苷酸及其突变体或变体编码的新的多核苷酸和多肽。 这些多核苷酸包含从人脾cDNA文库中分离的核酸序列（Hyseq克隆鉴定号2938352（SEQ ID NO：1））。 本发明的其它方面包括含有生产新的人分泌的CD84样多肽的方法的载体和对这些多肽特异的抗体。
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7.发明授权Methods and compositions concerning antibodies that bind CD84-like polypeptides 有权关于结合CD84样多肽的抗体的方法和组合物公开(公告)号：US07981413B2
公开(公告)日：2011-07-19
申请号：US12195282
申请日：2008-08-20
申请人： Chiaoyun Kuo , Bryan J. Boyle , Jian Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
发明人： Chiaoyun Kuo , Bryan J. Boyle , Jian Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
IPC分类号： A61K39/395
CPC分类号： C12N9/6432 , A61K38/00 , C07K14/70503 , C07K14/70596 , C07K14/715 , C07K16/00 , C12N9/16 , C12Y304/21006
摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译： 本发明提供由对应于新的人分泌的CD84样多肽的这种多核苷酸及其突变体或变体编码的新的多核苷酸和多肽。 这些多核苷酸包含从人脾cDNA文库中分离的核酸序列（Hyseq克隆鉴定号2938352（SEQ ID NO：1））。 本发明的其它方面包括含有生产新的人分泌的CD84样多肽的方法的载体和对这些多肽特异的抗体。
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8.发明申请Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides 审中-公开与CD84样多肽和多核苷酸相关的方法和材料公开(公告)号：US20080260747A1
公开(公告)日：2008-10-23
申请号：US12100870
申请日：2008-04-10
申请人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
发明人： Chiaoyun Kuo , Bryan J. Boyle , Jian-Rui Wang , Y. Tom Tang , Chenghua Liu , Radoje T. Drmanac
IPC分类号： A61K39/395 , C07K16/00 , A61P35/00
CPC分类号： C12N9/6432 , A61K38/00 , C07K14/70503 , C07K14/70596 , C07K14/715 , C07K16/00 , C12N9/16 , C12Y304/21006
摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译： 本发明提供由对应于新的人分泌的CD84样多肽的这种多核苷酸和突变体或其变体编码的新的多核苷酸和多肽。 这些多核苷酸包含从人脾cDNA文库中分离的核酸序列（Hyseq克隆鉴定号2938352（SEQ ID NO：1））。 本发明的其它方面包括含有生产新的人分泌的CD84样多肽的方法的载体和对这些多肽特异的抗体。
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公开(公告)号：US20070049743A1
公开(公告)日：2007-03-01
申请号：US10294433
申请日：2002-11-13
申请人： Y. Tang , Chenghua Liu , Vinod Asundi , Rui-Hung Chen , Feiyan Ren , Jian-Rui Wang , Tom Wehrman , Aidong Xue , Yonghong Yang , Jie Zhang , Qing Zhao , Ping Zhou , Radoje Drmanac , Ryle Goodrich
发明人： Y. Tang , Chenghua Liu , Vinod Asundi , Rui-Hung Chen , Feiyan Ren , Jian-Rui Wang , Tom Wehrman , Aidong Xue , Yonghong Yang , Jie Zhang , Qing Zhao , Ping Zhou , Radoje Drmanac , Ryle Goodrich
CPC分类号： C07K14/47 , A61K38/00 , A61K2039/505
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
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公开(公告)号：US20050239060A1
公开(公告)日：2005-10-27
申请号：US10122851
申请日：2002-04-12
申请人： Y. Tang , Chenghua Liu , Vinod Asundi , Jie Zhang , Feiyan Ren , Rui-hong Chen , Qing Zhao , Tom Wehrman , Aidong Xue , Yonghong Yang , Jian-Rui Wang , Ping Zhou , Yunqing Ma , Dunrui Wang , Zhiwei Wang , Radoje Drmanac
发明人： Y. Tang , Chenghua Liu , Vinod Asundi , Jie Zhang , Feiyan Ren , Rui-hong Chen , Qing Zhao , Tom Wehrman , Aidong Xue , Yonghong Yang , Jian-Rui Wang , Ping Zhou , Yunqing Ma , Dunrui Wang , Zhiwei Wang , Radoje Drmanac
CPC分类号： C07K14/47 , A61K2039/505
摘要： The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
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