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1.发明授权Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators 有权四氢吡啶 - 吡啶和四氢吡啶 - 嘧啶化合物及其作为C5a受体调节剂的用途公开(公告)号：US08846656B2
公开(公告)日：2014-09-30
申请号：US13553120
申请日：2012-07-19
申请人： Christopher Michael Adams , Veronique Darsigny , Alec Nathanson Flyer , Christine Fang Gelin , Timothy Brian Hurley , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Erik Meredith , Chang Rao , Michael H. Serrano-Wu , Catherine Fooks Solovay
发明人： Christopher Michael Adams , Veronique Darsigny , Alec Nathanson Flyer , Christine Fang Gelin , Timothy Brian Hurley , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Erik Meredith , Chang Rao , Michael H. Serrano-Wu , Catherine Fooks Solovay
IPC分类号： C07D471/04 , C07D491/107 , C07D491/044 , C07D471/10 , C07D471/08
CPC分类号： C07D471/04 , C07D471/08 , C07D471/10 , C07D491/044 , C07D491/107
摘要： The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供式I化合物：（I）制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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2.发明申请TETRAHYDROPYRIDO-PYRIDINE AND TETRAHYDROPYRIDO-PYRIMIDINE COMPOUNDS AND USE THEREOF AS C5A RECEPTOR MODULATORS 有权四氢吡啶并吡啶和四氢吡啶并吡啶化合物及其作为C5A受体调节剂的用途公开(公告)号：US20130184253A1
公开(公告)日：2013-07-18
申请号：US13553120
申请日：2012-07-19
申请人： Christopher Michael ADAMS , Veronique DARSIGNY , Alec Nathanson FLYER , Christine Fang GELIN , Timothy Brian Hurley , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Erik MEREDITH , Chang RAO , Michael H. SERRANO-WU , Catherine Fooks SOLOVAY
发明人： Christopher Michael ADAMS , Veronique DARSIGNY , Alec Nathanson FLYER , Christine Fang GELIN , Timothy Brian Hurley , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Erik MEREDITH , Chang RAO , Michael H. SERRANO-WU , Catherine Fooks SOLOVAY
IPC分类号： C07D471/04 , C07D491/107 , C07D491/044 , C07D471/10 , C07D471/08
CPC分类号： C07D471/04 , C07D471/08 , C07D471/10 , C07D491/044 , C07D491/107
摘要： The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供式I化合物：（I）制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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3.发明授权Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5A receptor modulators 有权四氢吡啶并吡啶和四氢吡啶并嘧啶化合物及其作为C5A受体调节剂的用途公开(公告)号：US09505755B2
公开(公告)日：2016-11-29
申请号：US14455848
申请日：2014-08-08
申请人： Christopher Michael Adams , Veronique Darsigny , Alec Nathanson Flyer , Christine Fang Gelin , Timothy Brian Hurley , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Erik Meredith , Chang Rao , Michael H. Serrano-Wu , Catherine Fooks Solovay
发明人： Christopher Michael Adams , Veronique Darsigny , Alec Nathanson Flyer , Christine Fang Gelin , Timothy Brian Hurley , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Erik Meredith , Chang Rao , Michael H. Serrano-Wu , Catherine Fooks Solovay
IPC分类号： C07D471/04 , C07D491/107 , C07D491/044 , C07D471/10 , C07D471/08
CPC分类号： C07D471/04 , C07D471/08 , C07D471/10 , C07D491/044 , C07D491/107
摘要： The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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4.发明申请TETRAHYDROPYRIDO-PYRIDINE AND TETRAHYDROPYRIDO-PYRIMIDINE COMPOUNDS AND USE THEREOF AS C5A RECEPTOR MODULATORS 审中-公开四氢吡啶并吡啶和四氢吡啶并吡啶化合物及其作为C5A受体调节剂的用途公开(公告)号：US20140349995A1
公开(公告)日：2014-11-27
申请号：US14455848
申请日：2014-08-08
申请人： Christopher Michael ADAMS , Veronique DARSIGNY , Alec Nathanson FLYER , Christine Fang GELIN , Timothy Brian HURLEY , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Erik MEREDITH , Chang RAO , Michael H. SERRANO-WU , Catherine Fooks SOLOVAY
发明人： Christopher Michael ADAMS , Veronique DARSIGNY , Alec Nathanson FLYER , Christine Fang GELIN , Timothy Brian HURLEY , Nan JI , Rajeshri Ganesh KARKI , Toshio KAWANAMI , Erik MEREDITH , Chang RAO , Michael H. SERRANO-WU , Catherine Fooks SOLOVAY
IPC分类号： C07D471/04 , C07D491/107 , C07D491/044
CPC分类号： C07D471/04 , C07D471/08 , C07D471/10 , C07D491/044 , C07D491/107
摘要： The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供式I化合物：制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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5.发明申请Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof 审中-公开氨基甲基 - 二芳基衍生物补体因子D抑制剂及其用途公开(公告)号：US20160145247A1
公开(公告)日：2016-05-26
申请号：US14904693
申请日：2014-07-17
申请人： David B. BELANGER , Stefanie FLOHR , Christine Fang GELIN , Keith JENDZA , Nan JI , Donglei LIU , Edwige Lilliane Jeanne LORTHIOIS , Rakeshri Ganesh KARKI , Nello MAINOLFI , James J. POWERS , Stefan Andreas RANDL , Olivier ROGEL , Anna VULPETTI , Taeyoung YOON
发明人： David Belanger , Stefanie Flohr , Christine Fang Gelin , Keith Jendza , Nan Ji , Rajeshri Ganesh Karki , Donglei Liu , Edwoge Liliane Jeanne LORTHIOIS , Nello Mainolfi , James J. Powers , Stefan Andreas Randi , Oliver Rogel , Anna Vulpetti , Taeyoung YOON
IPC分类号： C07D417/12 , C07C237/42 , C07D263/32 , C07D213/56 , C07D231/12 , C07D307/16 , C07D213/81 , C07D277/56 , C07D213/82 , C07D233/90 , C07D405/12 , C07C311/37 , C07D239/26 , C07D309/14 , C07D309/06 , C07C229/34 , C07D311/42 , C07D317/60 , C07D231/56 , C07D257/04 , C07D265/30 , C07D267/10 , C07D215/12 , C07D205/04 , C07D305/06 , C07C237/40
CPC分类号： C07D417/12 , C07C217/48 , C07C217/58 , C07C217/64 , C07C217/74 , C07C217/76 , C07C229/34 , C07C229/36 , C07C229/42 , C07C233/43 , C07C233/47 , C07C233/63 , C07C235/34 , C07C235/46 , C07C237/20 , C07C237/38 , C07C237/40 , C07C237/42 , C07C255/16 , C07C255/43 , C07C255/57 , C07C255/59 , C07C257/18 , C07C311/37 , C07C317/32 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07D205/04 , C07D213/56 , C07D213/81 , C07D213/82 , C07D215/12 , C07D231/12 , C07D231/56 , C07D233/90 , C07D239/26 , C07D257/04 , C07D263/32 , C07D265/30 , C07D267/10 , C07D277/56 , C07D305/06 , C07D307/16 , C07D309/06 , C07D309/14 , C07D311/42 , C07D317/60 , C07D405/12
摘要： The present invention provides a compound of formula (I), a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供了式（I）化合物，本发明化合物的制备方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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