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1.发明授权Method for producing extracts of Boehmeria frutescens thunberg or Boehmeria nivea for hepatitis treatment 有权生产Boehmeria frutescens thunberg或Boehmeria nivea提取物用于肝炎治疗的方法公开(公告)号：US07431946B2
公开(公告)日：2008-10-07
申请号：US10997894
申请日：2004-11-29
申请人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
发明人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
IPC分类号： A61K36/00
CPC分类号： A61K36/185
摘要： A pharmaceutical mixture for the treatment of hepatitis and its preparation method are disclosed. The method includes the following steps: pulverize the plants, macerate and extract the plant with water, concentrate the aqueous extract as the first concentrate; add ethanol to form a precipitate, collect and concentrate the liquid phase to form the second concentrate, and dry it; pass the second concentrate through the resin, elute with water, water-ethanol mixture and ethanol, collect and concentrate the water-ethanol and ethanol elution fraction as the third concentrate, and dry it. The plants in the present invention are Boehmeria frutescens Thunberg, Boehmeria nivea or the nettle family.
摘要翻译： 公开了用于治疗肝炎的药物混合物及其制备方法。 该方法包括以下步骤：用水粉碎植物，浸渍和提取植物，浓缩含水提取物作为第一浓缩物; 加入乙醇以形成沉淀物，收集并浓缩液相以形成第二浓缩物，并将其干燥; 将第二浓缩物通过树脂，用水，乙醇 - 乙醇混合物和乙醇洗脱，收集并浓缩水 - 乙醇和乙醇洗脱级分作为第三浓缩物，并干燥。 本发明的植物是Boehmeria frutescens Thunberg，Boehmeria nivea或荨麻科。
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公开(公告)号：US20130059382A1
公开(公告)日：2013-03-07
申请号：US13605361
申请日：2012-09-06
申请人： Pei-Yi TSAI , Yi-Hung Wen , Zhi-Jie Huang , Pei-Shan Li , Hsin-Hsin Shen , Yi-Hung Lin , Chu-Hsun Lu
发明人： Pei-Yi TSAI , Yi-Hung Wen , Zhi-Jie Huang , Pei-Shan Li , Hsin-Hsin Shen , Yi-Hung Lin , Chu-Hsun Lu
IPC分类号： A61K9/00 , A61K9/16 , A61K31/07 , A61K31/23 , A61K31/22 , A61K38/16 , A61K38/02 , A61K31/7088 , A61K38/19 , A61K35/16 , A61K35/14 , A61K35/12 , A61P19/08 , C12N5/071 , A61K9/14
CPC分类号： A61L27/10 , A61L27/12 , A61L27/28 , A61L27/54 , A61L2300/624 , A61L2400/12 , C12N5/0068
摘要： In an embodiment of the disclosure, a biomedical material is provided. The biomedical material includes a biocompatible material having a surface and a carrier distributed over the surface of the biocompatible material, wherein both of the biocompatible material and the carrier have no charges, one of them has charges or both of them have charges with different electricity. The biomedical material is utilized for dentistry, orthopedics, wound healing or medical beauty and applied in the repair and regeneration of various soft and hard tissues.
摘要翻译： 在本公开的一个实施方案中，提供生物医学材料。 生物医学材料包括具有分布在生物相容性材料的表面上的表面和载体的生物相容性材料，其中生物相容性材料和载体都不具有电荷，其中之一具有电荷，或者两者都具有不同电荷的电荷。 生物医学材料用于牙科，骨科，伤口愈合或医疗美容，并用于各种软组织和硬组织的修复和再生。
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3.发明授权公开(公告)号：US07799353B2
公开(公告)日：2010-09-21
申请号：US12071076
申请日：2008-02-15
申请人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
发明人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
IPC分类号： A61K36/00
CPC分类号： A61K36/185
摘要： A pharmaceutical mixture for the treatment of hepatitis and its preparation method are disclosed. The method includes the following steps: pulverize the plants, macerate and extract the plant with water, concentrate the aqueous extract as the first concentrate; add ethanol to form a precipitate, collect and concentrate the liquid phase to form the second concentrate, and dry it; pass the second concentrate through the resin, elute with water, water-ethanol mixture and ethanol, collect and concentrate the water-ethanol and ethanol elution fraction as the third concentrate, and dry it. The plants in the present invention are Boehmeria frutescens Thunberg, Boehmeria nivea or the nettle family.
摘要翻译： 公开了用于治疗肝炎的药物混合物及其制备方法。 该方法包括以下步骤：用水粉碎植物，浸渍和提取植物，浓缩含水提取物作为第一浓缩物; 加入乙醇以形成沉淀物，收集并浓缩液相以形成第二浓缩物，并将其干燥; 将第二浓缩物通过树脂，用水，乙醇 - 乙醇混合物和乙醇洗脱，收集并浓缩水 - 乙醇和乙醇洗脱级分作为第三浓缩物，并干燥。 本发明的植物是Boehmeria frutescens Thunberg，Boehmeria nivea或荨麻科。
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4.发明申请公开(公告)号：US20080138445A1
公开(公告)日：2008-06-12
申请号：US12071076
申请日：2008-02-15
申请人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
发明人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
CPC分类号： A61K36/185
摘要： A pharmaceutical mixture for the treatment of hepatitis and its preparation method are disclosed. The method includes the following steps: pulverize the plants, macerate and extract the plant with water, concentrate the aqueous extract as the first concentrate; add ethanol to form a precipitate, collect and concentrate the liquid phase to form the second concentrate, and dry it; pass the second concentrate through the resin, elute with water, water-ethanol mixture and ethanol, collect and concentrate the water-ethanol and ethanol elution fraction as the third concentrate, and dry it. The plants in the present invention are Boehmeria frutescens Thunberg, Boehmeria nivea or the nettle family.
摘要翻译： 公开了用于治疗肝炎的药物混合物及其制备方法。 该方法包括以下步骤：用水粉碎植物，浸渍和提取植物，浓缩含水提取物作为第一浓缩物; 加入乙醇以形成沉淀物，收集并浓缩液相以形成第二浓缩物，并将其干燥; 将第二浓缩物通过树脂，用水，乙醇 - 乙醇混合物和乙醇洗脱，收集并浓缩水 - 乙醇和乙醇洗脱级分作为第三浓缩物，并干燥。 本发明的植物是Boehmeria frutescens Thunberg，Boehmeria nivea或荨麻科。
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5.发明申请HERBAL EXTRACTS WHICH INDUCE IMMUNE CELLS TO PRODUCE INTERFERON AND ACTIVATE TOLL-LIKE RECEPTORS 审中-公开诱导免疫细胞产生干扰素和激活类似受体的草药提取物公开(公告)号：US20090280200A1
公开(公告)日：2009-11-12
申请号：US12164958
申请日：2008-06-30
申请人： I Horng PAN , Lain-Tze LEE , Chih-Lung CHEN , Hsin-Jan YAO , Chu-Hsun LU , Chen Hsuan LIN , Ya-Yan YANG , Hsin-Hsin SHEN , Ming-Feng CHEN
发明人： I Horng PAN , Lain-Tze LEE , Chih-Lung CHEN , Hsin-Jan YAO , Chu-Hsun LU , Chen Hsuan LIN , Ya-Yan YANG , Hsin-Hsin SHEN , Ming-Feng CHEN
CPC分类号： A61K36/65 , A61K36/233 , A61K36/484 , A61K36/539 , A61K36/79 , A61K2300/00
摘要： An herbal extract which induces immune cells to produce interferon and activates Toll-like receptors and a preparation method thereof are provided. The herbal extract is extracted from an effective amount of raw material including Glycyrrhizae Radix, Bupleuri Radix, Scutellariae Radix, Schisandrae Fructus and Paeoniae Rubra Radix. Glycyrrhizae Radix, Bupleuri Radix, Scutellariae Radix, Schisandrae Fructus and Paeoniae Rubra Radix have a weight ratio of 1-5:1-5:1-5:1-3:1-3.
摘要翻译： 提供诱导免疫细胞产生干扰素并激活Toll样受体的草药提取物及其制备方法。 从有效量的原料中提取草药提取物，包括甘草，白芍，黄芩，五味子和芍药。 甘草，柴胡，黄芩，五味子和芍药的重量比为1-5：1-5：1-5：1-3：1-3。
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公开(公告)号：US07150886B2
公开(公告)日：2006-12-19
申请号：US10646793
申请日：2003-08-25
申请人： I-Horng Pan , Hsi-Ho Chiou , Chu-Hsun Lu , Chaurp-Ting Ju , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
发明人： I-Horng Pan , Hsi-Ho Chiou , Chu-Hsun Lu , Chaurp-Ting Ju , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
IPC分类号： A61K36/00
CPC分类号： A61K36/282 , A61K36/744
摘要： The present invention relates to a composition for liver protection and a preparing method of the same, the processes are as follows: grinding Artemisiae Capillaris and Gardeniae Fructus, mixing with pure water, and boiling the mixture. Then, adding the Rhei Rhizoma alcohol solution into the mixture for extraction to form the first solid phase and the first liquid phase, further concentrating the first liquid phase to form a concentrate, and adding alcohol into the concentrate for precipitation to form the second solid phase and second liquid phase, and separating the second solid phase and drying.
摘要翻译： 本发明涉及一种肝保护用组合物及其制备方法，其工艺如下：将蒿蒿和栀子粉研磨，与纯水混合，煮沸混合物。 然后，将Rhei Rhizoma醇溶液加入到混合物中以进行萃取以形成第一固相和第一液相，进一步浓缩第一液相以形成浓缩物，并向浓缩物中加入酒精沉淀形成第二固相 和第二液相，并分离第二固相并干燥。
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7.发明申请公开(公告)号：US20050142222A1
公开(公告)日：2005-06-30
申请号：US10997894
申请日：2004-11-29
申请人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
发明人： I-Horng Pan , Yu-Ming Hsieh , Zhi-Jie Huang , Hsi-Ho Chiu , Chaur-Ting Ju , Chu-Hsun Lu , Pei-Yi Tsai , Wei-Lun Fan , Wen-Huang Peng , Ming-Tsuen Hsieh
CPC分类号： A61K36/185
摘要： A pharmaceutical mixture for the treatment of hepatitis and its preparation method are disclosed. The method includes the following steps: pulverize the plants, macerate and extract the plant with water, concentrate the aqueous extract as the first concentrate; add ethanol to form a precipitate, collect and concentrate the liquid phase to form the second concentrate, and dry it; pass the second concentrate through the resin, elute with water, water-ethanol mixture and ethanol, collect and concentrate the water-ethanol and ethanol elution fraction as the third concentrate, and dry it. The plants in the present invention are Boehmeria frutescens Thunberg, Boehmeria nivea or the nettle family.
摘要翻译： 公开了用于治疗肝炎的药物混合物及其制备方法。 该方法包括以下步骤：用水粉碎植物，浸渍和提取植物，浓缩含水提取物作为第一浓缩物; 加入乙醇以形成沉淀物，收集并浓缩液相以形成第二浓缩物，并将其干燥; 将第二浓缩物通过树脂，用水，乙醇 - 乙醇混合物和乙醇洗脱，收集并浓缩水 - 乙醇和乙醇洗脱级分作为第三浓缩物，并干燥。 本发明的植物是Boehmeria frutescens Thunberg，Boehmeria nivea或荨麻科。
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公开(公告)号：US06635758B2
公开(公告)日：2003-10-21
申请号：US10042311
申请日：2002-01-11
申请人： I-Hong Pan , Chu-Hsun Lu , Hsi-Ho Chiu , Lain-Tze Lee , Hsin-Jan Yao
发明人： I-Hong Pan , Chu-Hsun Lu , Hsi-Ho Chiu , Lain-Tze Lee , Hsin-Jan Yao
IPC分类号： C07H106
CPC分类号： C07H1/08
摘要： An aqueous two-phase system for extracting glycosides from a herb includes the extractive solution, about 5 wt %-30 wt % of salt, about 5 wt %-30 wt % of polyol and selectively about 0 wt %-30 wt % of alcohols. The salt can be dihydrogen phosphate, hydrogen phosphate and phosphate or a mixture thereof, and it also can be sulfates, chlorides, oxalates, or acetates. In addition, a process for extracting glycosides using an aqueous two-phase system is disclosed. The procedures includes preparation of extractive solution, concentration, phase separation, drying, washing with solvent, cooling, filtration and drying of the final products.
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