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1.发明申请公开(公告)号：US20140030724A1
公开(公告)日：2014-01-30
申请号：US14111159
申请日：2012-04-11
申请人： Chui Yee Fong , Ariffeen Bongso , Mahesh Choolani , Zhouwei Huang , Gauthaman Kalamegam , Sukumar Ponnusamy
发明人： Chui Yee Fong , Ariffeen Bongso , Mahesh Choolani , Zhouwei Huang , Gauthaman Kalamegam , Sukumar Ponnusamy
IPC分类号： G01N33/50
CPC分类号： G01N33/5094 , C12N5/0647 , G01N2800/00
摘要： There is provided a method of identifying at least one foetal erythroblast in a sample, the method comprising analysing the morphology of at least one cell in the sample; wherein at least one analysed cell that is nucleated, is CD45 negative and comprises a relatively high cytoplasmic to nuclear ratio is identified as the foetal erythroblast.
摘要翻译： 提供了一种鉴定样品中至少一种胎儿成红细胞的方法，所述方法包括分析样品中至少一种细胞的形态; 其中被成核的至少一个经分析的细胞是CD45阴性并且包含相对高的细胞质与核比，被鉴定为胎儿成红细胞。
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公开(公告)号：US20050164383A1
公开(公告)日：2005-07-28
申请号：US11048607
申请日：2005-02-01
CPC分类号： C12N5/0652 , A61K35/12 , C12N5/0606 , C12N2502/13 , C12N2506/02
摘要： The present invention relates to undifferentiated human embryonic stem cells, methods of cultivation and propagation, production of differentiated cells and in particular the production of human embryonic stem cells capable of yielding somatic differentiated cells in vitro, as well as committed progenitor cells capable of giving rise to mature somatic cells and uses thereof. The present invention also provides a purified preparation of undifferentiated human embryonic stem cells capable of proliferation in vitro. Furthermore, the present invention provides a somatic cell differentiated in vitro from an undifferentiated embryonic stem cell. There is also provided a committed progenitor cell capable of giving rise to mature somatic cells.
摘要翻译： 本发明涉及未分化的人类胚胎干细胞，培养和繁殖方法，分化细胞的产生，特别是能够在体外产生体细胞分化细胞的人类胚胎干细胞的产生，以及能够产生的定型的祖细胞 成熟体细胞及其用途。 本发明还提供能够在体外增殖的未分化的人胚胎干细胞的纯化制剂。 此外，本发明提供了体外与未分化的胚胎干细胞分化的体细胞。 还提供了能够产生成熟体细胞的致死祖细胞。
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公开(公告)号：US06875607B1
公开(公告)日：2005-04-05
申请号：US09436164
申请日：1999-11-09
申请人： Benjamin Eithan Reubinoff , Martin Frederick Pera , Chui-Yee Fong , Alan Osborne Trounson , Ariffeen Bongso
发明人： Benjamin Eithan Reubinoff , Martin Frederick Pera , Chui-Yee Fong , Alan Osborne Trounson , Ariffeen Bongso
IPC分类号： C12N15/09 , A61K35/12 , C12N5/02 , C12N5/0735 , C12N5/077 , C12N5/10 , C12R1/91 , A01N1/00 , C12N5/00
CPC分类号： C12N5/0652 , A61K35/12 , C12N5/0606 , C12N2502/13 , C12N2506/02
摘要： The present invention relates to undifferentiated human embryonic stem cells, methods of cultivation and propagation, production of differentiated cells and in particular the production of human embryonic stem cells capable of yielding somatic differentiated cells in vitro, as well as committed progenitor cells capable of giving rise to mature somatic cells and uses thereof. The present invention also provides a purified preparation of undifferentiated human embryonic stem cells capable of proliferation in vitro. Furthermore, the present invention provides a somatic cell differentiated in vitro from an undifferentiated embryonic stem cell. There is also provided a committed progenitor cell capable of giving rise to mature somatic cells.
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公开(公告)号：US09910032B2
公开(公告)日：2018-03-06
申请号：US14111159
申请日：2012-04-11
申请人： Chui Yee Fong , Ariffeen Bongso , Mahesh Choolani , Zhouwei Huang , Gauthaman Kalamegam , Sukumar Ponnusamy
发明人： Chui Yee Fong , Ariffeen Bongso , Mahesh Choolani , Zhouwei Huang , Gauthaman Kalamegam , Sukumar Ponnusamy
IPC分类号： G01N33/50 , C12N5/0789
CPC分类号： G01N33/5094 , C12N5/0647 , G01N2800/00
摘要： There is provided a method of identifying at least one foetal erythroblast in a sample, the method comprising analyzing the morphology of at least one cell in the sample; wherein at least one analyzed cell that is nucleated, is CD45 negative and comprises a relatively high cytoplasmic to nuclear ratio is identified as the foetal erythroblast.
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