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    NOVEL USE
    1.
    发明申请
    NOVEL USE 有权

    公开(公告)号：US20250161184A1

    公开(公告)日：2025-05-22

    申请号：US18832718

    申请日：2023-01-27

    Applicant: DSM IP Assets B.V.

    Inventor： Leithe BUDEL

    IPC: A61K8/60 ,  A61Q19/08

    Abstract: The present invention relates to the use of neutral core human milk oligosaccharides such as in particular lacto-N-(neo)tetraoses as anti-ageing active ingredient as well as the use thereof in topical anti-ageing compositions.

    TEXTURIZED VEGETABLE PROTEIN
    3.
    发明申请
    TEXTURIZED VEGETABLE PROTEIN 有权

    公开(公告)号：US20250143350A1

    公开(公告)日：2025-05-08

    申请号：US18839700

    申请日：2023-02-16

    Applicant: DSM IP Assets B.V.

    Inventor： Arjen SEIN ,  Linda DE LANGE

    IPC: A23J3/22 ,  A23J3/14 ,  A23J3/26

    Abstract: The invention relates to a dry extrusion process for preparing a texturized vegetable protein, to a composition comprising rapeseed protein, a legume-derived protein, and a plant-based fiber, to the use of said composition in the preparation of a meat alternative and to meat alternatives.

    POLYURETHANE EXCIPIENT
    5.
    发明申请
    POLYURETHANE EXCIPIENT 有权

    公开(公告)号：US20250114459A1

    公开(公告)日：2025-04-10

    申请号：US18984821

    申请日：2024-12-17

    Applicant: DSM IP Assets B.V.

    Inventor： Jennifer AL-RASHID ,  Jacob RIFFEY ,  John Andrew ZUPANCICH

    IPC: A61L31/06 ,  A61L29/06 ,  C08G18/12 ,  C08G18/32 ,  C08G18/44 ,  C08G18/48

    Abstract: In an embodiment, a polyurethane comprises the residues of i. an aliphatic diisocyanate, ii. an aliphatic diol comprising a poly(ethylene oxide) moiety, iii. an aliphatic diol comprising a polycarbonate moiety, and iv. a chain extender, wherein the polyurethane has a melting temperature of 140° C. or less and has a weight average molecular weight of from 100,000 to 500,000 g/mol. In an embodiment, the polyurethane is substantially devoid of catalyst. In an embodiment, the polyurethane is formed by reactive extrusion. In an embodiment, a medical device comprises the polyurethane and a bioactive agent. The medical devices, methods, and polyurethanes may exhibit benefits in end-product biostability, drug release profile, health and safety, and processing speed or reproducibility.

    25-HYDROXYVITAMIN D AS A FEED ADDITIVE FOR AQUATIC ANIMALS
    6.
    发明申请
    25-HYDROXYVITAMIN D AS A FEED ADDITIVE FOR AQUATIC ANIMALS 有权

    公开(公告)号：US20250099490A1

    公开(公告)日：2025-03-27

    申请号：US18730645

    申请日：2023-01-23

    Applicant: DSM IP Assets B.V.

    Inventor： Sebastien RIDER ,  Eduardo Yugo YAMASHITA

    IPC: A61K31/593 ,  A23K20/158 ,  A23K20/174 ,  A23K40/25 ,  A23K40/30 ,  A23K50/80 ,  A61K47/44

    Abstract: The present invention relates to a composition for aquatic animals comprising as active ingredient 25-hydroxyvitamin D, preferably 25-hydroxy vitamin D3 (25-OH D3). The present invention further relates to the use of 25-hydroxyvitamin D, preferably 25-hydroxyvitamin D3 (25-OH D3), as feed additive for aquatic animals including fish and shrimp. More particular, this invention relates to the use of 25-hydroxyvitamin D, preferably 25-hydroxyvitamin D3 (25-OH D3), for improving feed utilization and growth and performance parameters of the animals, such as the feed conversion ratio (FOR). Immunity, protein efficiency ratio (PER), specific growth rate (SGR), final body weight, feed efficiency (FE), nutrient utilization, body protein content, and/or carcass yield and/or for increasing levels of Vitamin D, preferably Vitamin D3, in the blood of aquatic animals.

    Settable bone void filler
    9.
    发明授权
    Settable bone void filler 有权

    公开(公告)号：US12239762B2

    公开(公告)日：2025-03-04

    申请号：US17845141

    申请日：2022-06-21

    Applicant: DSM IP Assets B.V.

    Inventor： Andrew Fallis ,  Steven Leonhardt ,  Justin Kontra ,  Rakesh Batish ,  Timothy Ringeisen

    IPC: A61L27/46 ,  A61L27/52 ,  A61L27/58

    Abstract: The invention provides composite materials that form a biocompatible and bioresorbable settable ceramic-forming composition, and that possesses high strength when set and other desirable mechanical properties. The composite materials may include additive materials that provide beneficial advantages in the handling and physical properties of the material. When a hydrated precursor, the composite material is capable of being injected through cannulas for placement in treatment sites. The composite material provided desirable handling properties and sets in a clinically relevant time period.

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