公开(公告)号：US20120067815A1

公开(公告)日：2012-03-22

申请号：US13120298

申请日：2009-09-23

Applicant: David Luttropp ,  Bernd Krause ,  Markus Neubauer ,  Reinhold Deppisch ,  Doris Deppisch ,  Andrea Schnell ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer

Inventor： David Luttropp ,  Bernd Krause ,  Markus Neubauer ,  Reinhold Deppisch ,  Doris Deppisch ,  Andrea Schnell ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer

IPC: A61M1/16 ,  B01D63/04 ,  B01D61/28 ,  B01D61/24 ,  A61M1/14

CPC classification number: A61M1/3472 ,  A61M1/3489 ,  A61M1/3687 ,  A61M1/3689 ,  B01D69/08 ,  B01D69/144 ,  C12N5/0686 ,  C12N2500/14 ,  C12N2500/84 ,  C12N2501/11 ,  C12N2533/30

Abstract: A bioartificial kidney equivalent and a process for producing the bioartificial kidney equivalent. The hybrid bioartificial kidney comprises human proximal and distal renal tubule cells grown on particular synthetic membranes.

Abstract translation: 生物人造肾等效物和生物人造肾当量的生产方法。 混合生物人造肾包括在特定合成膜上生长的人近端和远端的肾小管细胞。

公开(公告)号：US08696909B2

公开(公告)日：2014-04-15

申请号：US13120298

申请日：2009-09-23

Applicant: David Luttropp ,  Bernd Krause ,  Markus Neubauer ,  Andrea Schnell ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer ,  Doris Deppisch

Inventor： David Luttropp ,  Bernd Krause ,  Markus Neubauer ,  Reinhold Deppisch ,  Andrea Schnell ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer

IPC: A61M1/18 ,  A61M1/34 ,  B01D61/24 ,  B01D61/28 ,  B01D63/04 ,  B01D71/76 ,  B01D71/82 ,  C12M3/04 ,  C12M3/06

CPC classification number: A61M1/3472 ,  A61M1/3489 ,  A61M1/3687 ,  A61M1/3689 ,  B01D69/08 ,  B01D69/144 ,  C12N5/0686 ,  C12N2500/14 ,  C12N2500/84 ,  C12N2501/11 ,  C12N2533/30

Abstract: A bioartificial kidney equivalent and a process for producing the bioartificial kidney equivalent. The hybrid bioartificial kidney comprises human proximal and distal renal tubule cells grown on particular synthetic membranes.

Abstract translation: 生物人造肾等效物和生物人造肾当量的生产方法。 混合生物人造肾包括在特定合成膜上生长的人近端和远端的肾小管细胞。

公开(公告)号：US09902939B2

公开(公告)日：2018-02-27

申请号：US13120323

申请日：2009-09-23

Applicant: David Luttropp ,  Markus Neubauer ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer ,  Reinhold Deppisch ,  Doris Deppisch

Inventor： David Luttropp ,  Markus Neubauer ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer ,  Reinhold Deppisch ,  Doris Deppisch

IPC: C12M3/00 ,  B01D71/42 ,  C12N5/071 ,  C12M1/12 ,  C12M1/00 ,  B01D71/68

CPC classification number: C12N5/0686 ,  B01D71/42 ,  B01D71/68 ,  C12M21/08 ,  C12M25/10 ,  C12M29/16 ,  C12N2533/30

Abstract: A device for culturing, storing and expanding adherent renal cells. The device permits the adhesion and proliferation of the cells and the surface characteristics of the membrane material used in said device further permit the cellular matrix components (EMC). A method for expanding adherent renal cells and methods of using particular membranes for culturing, storing and expanding adherent renal cells. The membranes comprise a copolymer of acrylonitrile and sodium methallyl sulfonate as well as polyethylenimine.

公开(公告)号：US20120145626A1

公开(公告)日：2012-06-14

申请号：US13120323

申请日：2009-09-23

Applicant: David Luttropp ,  Markus Neubauer ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer ,  Reinhold Deppisch ,  Doris Deppisch

Inventor： David Luttropp ,  Markus Neubauer ,  Helmut Geiger ,  Juergen Bereiter-Hahn ,  Patrick Baer ,  Reinhold Deppisch ,  Doris Deppisch

IPC: C12N5/071 ,  B01D71/66 ,  B01D71/42 ,  C12M3/00 ,  B01D71/58

CPC classification number: C12N5/0686 ,  B01D71/42 ,  B01D71/68 ,  C12M21/08 ,  C12M25/10 ,  C12M29/16 ,  C12N2533/30

Abstract: A device for culturing, storing and expanding adherent renal cells. The device permits the adhesion and proliferation of the cells and the surface characteristics of the membrane material used in said device further permit the cellular matrix components (EMC). A method for expanding adherent renal cells and methods of using particular membranes for culturing, storing and expanding adherent renal cells. The membranes comprise a copolymer of acrylonitrile and sodium methallyl sulfonate as well as polyethylenimine.

Abstract translation: 用于培养，储存和扩增粘附性肾细胞的装置。 该装置允许细胞的粘附和增殖，并且所述装置中使用的膜材料的表面特性进一步允许细胞基质组分（EMC）。 用于扩增粘附性肾细胞的方法和使用特定膜培养，储存和扩增粘附性肾细胞的方法。 膜包括丙烯腈和甲代烯丙基磺酸钠的共聚物以及聚乙烯亚胺。

公开(公告)号：US5982385A

公开(公告)日：1999-11-09

申请号：US903607

申请日：1997-07-31

Applicant: Keith Fish ,  David Luttropp

Inventor： Keith Fish ,  David Luttropp

IPC: G06T15/00 ,  G06T17/20 ,  G06F15/00

CPC classification number: G06T17/20

Abstract: A geometrical object representation system efficiently represents primitives for a computer graphics system in order to generate a display of a desired geometrical object surface. A data list repository is configured to maintain a linked list of strip primitives received from an application program. A strip builder traverses the linked list searching for matching vertices of unmatched strips. The strip builder uses a logic manipulation to quickly exclude obvious non-matches. After finding two strips with matching vertices, strip builder joins the two strips together. This joining process creates larger strips which represent the geometrical object in a more compact and efficient form. A graphics system can use this more efficient form of data to reduce data calls and decrease run time in processing the data for rendering by a display.

Abstract translation: 几何对象表示系统有效地表示计算机图形系统的基元，以便产生期望的几何物体表面的显示。 数据列表存储库被配置为维护从应用程序接收的条带图元的链接列表。 条形图构建器遍历链接列表，搜索不匹配条带的匹配顶点。 条形构建器使用逻辑操作来快速排除明显的不匹配。 在找到具有匹配顶点的两个条带之后，条带构建器将两个条带连接在一起。 该连接过程产生更大的条，其以更紧凑和有效的形式表示几何对象。 图形系统可以使用这种更有效的数据形式来减少数据调用，并减少处理数据以供显示器渲染的运行时间。