Abstract:
A loader for a slingshot is disclosed, having a tubular magazine for holding pellets, the magazine having a reloading end and a dispensing end with an opening, an end cap for closing the magazine at the reloading end, a dispensing mechanism at the dispensing end for dispensing pellets into a pouch, the dispensing mechanism comprising two or more resilient fingers spaced around the opening for retaining and selectively releasing pellets, the fingers flexible from a closed to an open position by application of force, and apertures defined by the space between the fingers for accessing pellets wherein the pellets are gravity-fed within the magazine. A method of using the loader is also described.
Abstract:
A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Abstract:
A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
Abstract:
The present invention relates to a process for the preparation of diketopyrrolopyrroles of the formula (I), wherein A1, A2, A3 and A4 are as defined in the description of the present invention, to new diketopyrrolopyrroles of the general formula I obtainable by the process, and the use of the new diketopyrrolopyrroles of the general formula I for the preparation of inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, dye lasers and electroluminescent devices, or as fluorescent markers for immunoassays and fluorescent tracers for leak detection of fluids. Furthermore the present invention relates to diketopyrrolopyrrole analogues of the general formula (II), wherein A1, A2 and A3 are defined in the description of the present invention, which are intermediates in the process for the preparation of diketopyrrolopyrroles of the formula I and can be used as crystal growth regulators
Abstract:
A method, apparatus, and computer-readable medium for analyzing network data streams with parsers generated using script based parsers is provided. The script based parsers are used to analyze the captured frames of a network data stream and identify conversations in the frames. The script based parsers are written in a language that describes network protocols. A script interpreter interprets script to build a parser in the memory of a computing device. A parsing engine uses the protocol parsers stored in memory to parse frames. A capture engine captures frames for parsing and frames are organized into conversations. The parsing of frames is optimized by substituting data structure sizes for data structures that are not of interest in a particular parser.
Abstract:
The present invention relates to fluorescent diketopyrrolopyrrole analogues of the general formula (I), wherein A1 and A2 are C1–C18alkyl, C2–C18alkenyl, C2–C18alkynyl, C5–C8cycloalkyl, C5–C8cycloalkenyl, aryl or heteroaryl, A3 and A4 are independently of each other C1–C18alkyl, Ar3, —CR30R31—(CH2)m—Ar3, or Y—R32, wherein R30 and R31 independently of each other stand for hydrogen or C1–C4alkyl, or phenyl which can be substituted up to three times with C1–C3alkyl, Ar3 stands for aryl, in particular phenyl or 1- or 2-naphthyl, C5–C8cycloalkyl, in particular cyclohexyl, or heteroaryl, which can be substituted one to three times with C1–C8alkyl, C1–C8alkoxy, halogen or phenyl, which can be substituted with C1–C8alkyl or C1–C8alkoxy one to three times, and m stands for 0, 1, 2, 3 or 4, Y is C(O)— or SO2— and R32 is C1–C18alkyl, Ar3, or aralkyl and A3 can additionally be hydrogen, C1–C8alkyloxycarbonyl, such as tertbutoxycarbonyl, or aralkyloxycarbonyl, such as benzyloxycarbonyl, a process for their preparation and their use for the preparation of inks, colourants, pigmented plastics for coatings, non-impact printing material, colour filters, cosmetics, polymeric ink particles, toners, dye lasers and electroluminescent devices, or as fluorescent markers for immunoassays and fluorescent tracers for leak detection of fluids. The diketopyrrolopyrrole analogues of the general formula I show a high solid state fluorescence
Abstract:
A method for bonding or joining thermoplastic or thermoset polymeric materials is provided which comprises applying a layer of conductive material (16) at a joint or between surfaces of thermoplastic or thermoset polymeric materials (12, 14), introducing a current so as to raise the temperature of the polymeric material above its melting point, maintaining the current for a time sufficient to allow the polymeric material to become molten and thereby form the joint or bond, and then removing the current and allowing the joint or bond (15) to cool. The method is advantageous in that it provides a simple and inexpensive means of bonding thermoplastic or thermoset polymeric materials with a minimum of materials and equipment The method of the present invention can also be utilized so as to heat thermoplastic pipes and other devices made of thermoplastic materials.
Abstract:
The present invention comprises a metal frame system wherein each frame member has one or more integral adjusters configured for selective extension from the frame member in a direction that is perpendicular to the length of the member. Each adjuster comprises a support bar or member having a threaded central passage aligned with a bolt hole through the frame member. The adjuster also comprises a pair of concentric tubes including a hollow outer tube and a fully threaded inner tube. The outer tube is positioned between the bar and the front edge and is spot welded to the bar. The inner tube is welded to a large washer providing a bearing surface and positioned behind the bar and is threaded through the central threaded bar passage. By rotating the inner threaded tube, the large washer is selectively positioned behind the bar a distance which may be adjusted.
Abstract:
A method and apparatus for determining the quantity of a substance in a solution. An exemplary embodiment of the method includes the step of introducing a first sample of the solution into a cavity in which a working electrode is located. A constant potential is applied between the working electrode and a reference electrode in electrical contact with the first sample until such time as the current through the working electrode has decayed to a minimum. The applied constant potential is maintained as the first sample of the solution is replaced by a second sample of the solution in a manner such that the cavity remains filled with solution during the replacement procedure. The applied constant potential is maintained until such time as the current through the working electrode has again decayed to a minimum, and the total amount of the charge passing through the working electrode subsequent to the introduction of the second sample into the cavity is determined.
Abstract:
Extended release formulations of S-methyladenosylmethionine (SAMe) are provided, as are methods of treating various disorders using extended release SAMe formulations. The extended release formulations may be used to treat a variety of disorders, including liver disorders, psychiatric disorders and joint disorders. Thus, extended release SAMe formulations may be used to treat alcoholic liver disease, fatty liver disease, hepatitis, generalized anxiety disorder, obsessive compulsive disorder, post traumatic stress disorder, panic disorder, and depressive disorders such as depression (e.g. major clinical depression) and dysthymia.