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1.发明授权公开(公告)号：US08735075B2
公开(公告)日：2014-05-27
申请号：US13399706
申请日：2012-02-17
申请人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart De La Cruz
发明人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart De La Cruz
CPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
摘要： The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
摘要翻译： 本发明涉及癌症的检测或其发展风险的评估。 特别地，本发明通过鉴定受试者中的超微结构和分子标记来提供组合物和方法检测场致癌作用。
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公开(公告)号：US20140050724A1
公开(公告)日：2014-02-20
申请号：US14114205
申请日：2012-04-27
申请人： Hemant K. Roy , Ramesh K. Wali , Dhananjay Kunte
发明人： Hemant K. Roy , Ramesh K. Wali , Dhananjay Kunte
CPC分类号： A61K31/08 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/765 , A61K45/06 , C07C43/11 , C08L71/02 , C08L2203/02 , A61K2300/00
摘要： Compositions comprising polyethylene glycol (PEG) are disclosed for the prophylaxis and/or treatment of head and neck squamous cell carcinomas (HNSCC). Methods for the prophylaxis and/or treatment of HNSCC comprising administering an effective amount of PEG are also disclosed. Also disclosed are methods and compositions for suppressing the surface expression of EGFR using PEG.
摘要翻译： 公开了包含聚乙二醇（PEG）的组合物用于预防和/或治疗头颈鳞状细胞癌（HNSCC）。 还公开了预防和/或治疗HNSCC的方法，包括给予有效量的PEG。 还公开了用PEG抑制EGFR表面表达的方法和组合物。
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公开(公告)号：US20150292036A1
公开(公告)日：2015-10-15
申请号：US14747596
申请日：2015-06-23
申请人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
发明人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
CPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
摘要： The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
摘要翻译： 本发明涉及癌症的检测或其发展风险的评估。 特别地，本发明通过鉴定受试者中的超微结构和分子标记来提供组合物和方法检测场致癌作用。
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4.发明授权公开(公告)号：US09090933B2
公开(公告)日：2015-07-28
申请号：US14202919
申请日：2014-03-10
申请人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
发明人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
CPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
摘要： The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
摘要翻译： 本发明涉及癌症的检测或其发展风险的评估。 特别地，本发明通过鉴定受试者中的超微结构和分子标记来提供组合物和方法检测场致癌作用。
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公开(公告)号：US20140302514A1
公开(公告)日：2014-10-09
申请号：US14202919
申请日：2014-03-10
申请人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
发明人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart Angelo De la Cruz
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
摘要： The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
摘要翻译： 本发明涉及癌症的检测或其发展风险的评估。 特别地，本发明通过鉴定受试者中的超微结构和分子标记来提供组合物和方法检测场致癌作用。
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公开(公告)号：US20120214880A1
公开(公告)日：2012-08-23
申请号：US13399706
申请日：2012-02-17
申请人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart De La Cruz
发明人： Vadim Backman , Hariharan Subramanian , Dhwanil Damania , Hemant Roy , Dhananjay Kunte , Mart De La Cruz
IPC分类号： A61K45/00 , G01N21/41 , G01N21/17 , A61P35/00 , G01N21/00 , C40B30/04 , G01N21/64 , C12Q1/02 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , G01N21/41 , G01N21/64 , G01N21/6486 , G01N33/57407 , G01N33/57411 , G01N33/57419 , G01N33/57484
摘要： The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.
摘要翻译： 本发明涉及癌症的检测或其发展风险的评估。 特别地，本发明通过鉴定受试者中的超微结构和分子标记来提供组合物和方法检测场致癌作用。
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