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    LIR-9, a novel leukocyte immunoglobulin-like receptor
    2.
    发明授权
    LIR-9, a novel leukocyte immunoglobulin-like receptor 失效
    LIR-9，一种新型的白细胞免疫球蛋白样受体

    公开(公告)号：US07875703B2

    公开(公告)日：2011-01-25

    申请号：US11981947

    申请日：2007-10-31

    申请人： Dirk M. Anderson ,  Luis G. Borges

    发明人： Dirk M. Anderson ,  Luis G. Borges

    IPC分类号： C07K14/00

    CPC分类号： C07K14/70535 ,  A61K38/00 ,  C07K14/70503 ,  C07K2319/00

    摘要： A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.

    摘要翻译： 描述了免疫球蛋白超家族（LIR）多肽的新家族的免疫受体分子。 公开的是编码LIR家族成员及其推导的氨基酸序列的序列，由与定义的核苷酸序列杂交的DNA编码的多肽，用于产生LIR家族多肽的方法和针对LIR多肽的特异性抗体。 LIR家族成员可用于治疗与免疫功能受抑制相关的自身免疫疾病和疾病状态。

    Human cDNAs encoding polypeptides having kinase functions
    8.
    发明授权
    Human cDNAs encoding polypeptides having kinase functions 失效
    编码具有激酶功能的多肽的人cDNA

    公开(公告)号：US06387676B1

    公开(公告)日：2002-05-14

    申请号：US09509902

    申请日：2000-06-23

    申请人： G. Duke Virca ,  Timothy A. Bird ,  Dirk M. Anderson ,  John S. Marken

    发明人： G. Duke Virca ,  Timothy A. Bird ,  Dirk M. Anderson ,  John S. Marken

    IPC分类号： C12N900

    CPC分类号： C12N9/1205

    摘要： The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in phosphorylation reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, the use of such polypeptides in screening assays, and kits comprising these reagents.

    摘要翻译： 本发明涉及具有激酶功能的纯化和分离的人多肽，编码此类多肽的核酸，用于产生这些多肽的重组形式的方法，针对这些多肽产生的抗体，衍生自这些多肽的片段化肽，使用此类多肽和 磷酸化反应中的片段化肽和分子量标记，使用这些多肽和片段化肽作为肽断裂的对照，在筛选测定中使用此类多肽，以及包含这些试剂的试剂盒。