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19 条记录 (耗时 0.016 秒)

    Pivot joint
    1.
    发明授权
    Pivot joint 有权
    枢轴接头

    公开(公告)号：US08267616B2

    公开(公告)日：2012-09-18

    申请号：US12308927

    申请日：2007-07-11

    申请人： Duncan McGregor

    发明人： Duncan McGregor

    IPC分类号： B25G3/20

    CPC分类号： E05C3/043 ,  E05B3/00 ,  Y10T292/0961 ,  Y10T292/1084 ,  Y10T403/32606 ,  Y10T403/7051

    摘要： A pivot joint includes a first component (12) having a projecting boss form (16) and a second component (11) having an opening (25) for receiving the boss form (16). A headed fastener (32) and washer (27) engage with the boss form (16), which includes engagement elements (17) that dig into the washer (27) when the joint is assembled.

    摘要翻译： 枢转接头包括具有突出凸台形式（16）的第一部件（12）和具有用于接收凸台形式（16）的开口（25）的第二部件（11）。 头部紧固件（32）和垫圈（27）与凸台形式（16）接合，其包括当接头组装时挖入垫圈（27）的接合元件（17）。

    Process for making tabletted detergent compositions
    3.
    发明授权
    Process for making tabletted detergent compositions 失效
    制备压片洗涤剂组合物的方法

    公开(公告)号：US06177398B1

    公开(公告)日：2001-01-23

    申请号：US09319752

    申请日：1999-06-10

    申请人： Alasdair Duncan McGregor ,  Jane Margaret Warwick

    发明人： Alasdair Duncan McGregor ,  Jane Margaret Warwick

    IPC分类号： C11D1100

    CPC分类号： C11D17/0073 ,  C11D17/0086 ,  C11D17/0091

    摘要： A process for making a detergent tablet suitable for use in laundry or automatic dishwashing by tabletting a detergent composition comprising solid components which form a total particulate base detergent matrix and non-aqueous liquid components having viscosity of 1000 cp or less is disclosed. The process involves the steps of applying the non-aqueous liquid components having viscosity of 1000 cp or less onto a low porosity fraction selected from the total particulate base detergent matrix.

    摘要翻译： 公开了一种制备适合用于洗衣或自动餐具洗涤的洗涤剂片剂的方法，该洗涤剂片剂包含形成总颗粒基洗涤剂基质的固体组分和粘度为1000cp或更低的非水液体组分的洗涤剂组合物。 该方法包括将具有1000cp或更低的粘度的非水液体组分施加到选自总颗粒基洗涤剂基质中的低孔隙率组分的步骤。

    Pivot joint
    7.
    发明申请
    Pivot joint 有权
    枢轴接头

    公开(公告)号：US20100047009A1

    公开(公告)日：2010-02-25

    申请号：US12308927

    申请日：2007-07-11

    申请人： Duncan McGregor

    发明人： Duncan McGregor

    IPC分类号： F16C11/00 ,  E05C3/04

    CPC分类号： E05C3/043 ,  E05B3/00 ,  Y10T292/0961 ,  Y10T292/1084 ,  Y10T403/32606 ,  Y10T403/7051

    摘要： A pivot joint includes a first component (12) having a projecting boss form (16) and a second component (11) having an opening (25) for receiving the boss form (16). A headed fastener (32) and washer (27) engage with the boss form (16), which includes engagement elements (17) that dig into the washer (27) when the joint is assembled.

    摘要翻译： 枢转接头包括具有突出凸台形式（16）的第一部件（12）和具有用于接收凸台形式（16）的开口（25）的第二部件（11）。 头部紧固件（32）和垫圈（27）与凸台形式（16）接合，其包括当接头组装时挖入垫圈（27）的接合元件（17）。

    Chimeric binding peptide library screening method
    8.
    发明授权
    Chimeric binding peptide library screening method 失效
    嵌合结合肽库筛选方法

    公开(公告)号：US07312074B1

    公开(公告)日：2007-12-25

    申请号：US09486882

    申请日：1998-09-02

    申请人： Duncan McGregor

    发明人： Duncan McGregor

    IPC分类号： C12Q1/68 ,  C12N15/00

    CPC分类号： C07K14/70567 ,  C07K2319/00 ,  C12N15/1075

    摘要： There is described a method of isolating nucleotide sequences encoding target peptides from DNA libraries using DNA binding proteins to link the peptide to the sequence which encodes it. DNA libraries are prepared from cells encoding the protein of interest, or from synthetic DNA, and inserted into, or adjacent to, a DNA binding protein in an expression vector to create a chimeric fusion protein. Incorporation of the vector DNA into a carrier package, during expression of the chimeric fusion protein, results in the production of a peptide display carrier package (PDCP) displaying the DNA-bound fusion protein on the external surface of the carrier package. Employment of affinity purification techniques results in the PDCP particles containing sequences encoding the desired peptide to be selected and the desired nucleotide sequences obtained therefrom.

    摘要翻译： 描述了使用DNA结合蛋白从DNA文库分离编码靶肽的核苷酸序列以将肽连接到编码它的序列的方法。 从编码目标蛋白的细胞或合成的DNA制备DNA文库，并将其插入到表达载体中的DNA结合蛋白中或与DNA结合蛋白相邻，以产生嵌合融合蛋白。 在嵌合融合蛋白的表达期间将载体DNA并入载体包中导致在载体包装的外表面上显示DNA结合融合蛋白的肽显示载体包装（PDCP）的制备。 使用亲和纯化技术导致含有编码要选择的所需肽的序列的PDCP颗粒和由其获得的所需核苷酸序列。

    Membrane-Translocating Peptides
    9.
    发明申请
    Membrane-Translocating Peptides 有权
    膜 - 位移肽

    公开(公告)号：US20080287311A1

    公开(公告)日：2008-11-20

    申请号：US11996496

    申请日：2006-07-24

    申请人： David Coomber ,  Kevin Fitzgerald ,  Duncan McGregor ,  Chris Ullman ,  Tomas Leanderson

    发明人： David Coomber ,  Kevin Fitzgerald ,  Duncan McGregor ,  Chris Ullman ,  Tomas Leanderson

    IPC分类号： C40B30/04 ,  C07K14/00 ,  C07H21/00 ,  C12N5/06

    CPC分类号： C12N15/1075

    摘要： A method is provided for selecting membrane-translocating peptides (MTPs) from a peptide display library that are capable of crossing or penetrating a lipid membrane. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of nucleic acid-peptide complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide; the complexes are exposed to a population of membrane-encapsulated compartments, allowing a translocating reaction to occur; complexes that remain unassociated with the membrane are removed; optionally complexes that are associated with the membrane are removed; and internalised nucleic acid-peptide complexes are recovered. The membrane-encapsulated compartments may be artificial vesicles such as liposomes, or populations of one or more cell types.

    摘要翻译： 提供了从能够穿透或穿透脂质膜的肽展示文库中选择膜转位肽（MTP）的方法。 表达编码显示的肽的多个核酸构建体，导致形成多个核酸 - 肽复合物，每个复合物包含与编码所显示肽的相应核酸构建体相关联的至少一个显示的肽; 复合物暴露于膜包封的隔室群，允许发生易位反应; 与膜保持不相关的复合物被去除; 去除与膜相关的任选复合物; 并回收内化的核酸 - 肽复合物。 膜包封的隔室可以是人造囊泡，例如脂质体或一种或多种细胞类型的群体。