公开(公告)号：US11931325B2

公开(公告)日：2024-03-19

申请号：US15769472

申请日：2016-10-18

申请人： Eaderm Co., Ltd.

发明人： Shohei Shinozaki ,  Kentaro Shimokado

IPC分类号： A61K31/155 ,  A23L33/10 ,  A61K8/40 ,  A61K8/41 ,  A61K8/43 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49 ,  A61K8/60 ,  A61K8/63 ,  A61K8/64 ,  A61K31/131 ,  A61K31/145 ,  A61K31/197 ,  A61K31/198 ,  A61K31/435 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4453 ,  A61K31/573 ,  A61K31/713 ,  A61K39/395 ,  A61K45/06 ,  A61P17/14 ,  A61Q7/00 ,  C07C257/10 ,  C07C279/00 ,  C12Q1/26 ,  G01N33/50

CPC分类号： A61K31/155 ,  A23L33/10 ,  A61K8/40 ,  A61K8/41 ,  A61K8/43 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/496 ,  A61K8/606 ,  A61K8/63 ,  A61K8/64 ,  A61K31/131 ,  A61K31/145 ,  A61K31/197 ,  A61K31/198 ,  A61K31/435 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4453 ,  A61K31/573 ,  A61K31/713 ,  A61K39/395 ,  A61K45/06 ,  A61P17/14 ,  A61Q7/00 ,  C12Q1/26 ,  G01N33/5008 ,  C07C257/10 ,  C07C279/00 ,  G01N2333/90254 ,  G01N2500/04

摘要： Novel compositions that promote hair growth or hair restoration, and compositions that prevent hair loss. Compositions including an iNOS inhibitor as an active ingredient are provided. Advantageous affects for hair growth or hair restoration are obtained when a composition including an iNOS inhibitor as an active ingredient is administered to a mammal. For the iNOS inhibitor, a low-molecular compound, an antibody, or a nucleic acid drug such as an antisense oligonucleotide or siRNA may be used. A method of screening for effective substances for promotion of hair growth or hair restoration or prevention of hair loss is also provided.