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1.发明授权公开(公告)号：US06451573B1
公开(公告)日：2002-09-17
申请号：US09431499
申请日：1999-11-01
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
IPC分类号： C12N976
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein the PI precursor comprises at least three PI monomers and wherein at least one of the monomers has a chymotrypsin specific site and at least one other of the monomers has a trypsin specific site.
摘要翻译： 本发明一般涉及蛋白酶抑制剂，其前体和编码它的遗传序列。 更具体地，本发明涉及包含编码或与编码来自植物的II型丝氨酸蛋白酶抑制剂（PI）前体）的序列互补的核苷酸序列的核酸分子，其中PI前体包含至少三种PI单体 并且其中所述单体中的至少一种具有胰凝乳蛋白酶特异性位点，并且所述单体中的至少一种具有胰蛋白酶特异性位点。
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2.发明授权Cultured plant cell gums for food, pharmaceutical, cosmetic and industrial applications 失效用于食品，制药，化妆品和工业应用的培养植物细胞胶公开(公告)号：US06350594B1
公开(公告)日：2002-02-26
申请号：US09433857
申请日：1999-11-04
IPC分类号： C12P1900
CPC分类号： A61K8/73 , A61K8/99 , A61K9/0014 , A61K9/0019 , A61K47/36 , A61Q19/00 , C08B37/006 , C08L5/00 , C09D5/04 , C09D11/03 , C12P19/04
摘要： Certain cultured plant cell gums, including those produced in suspension culture of plant cells of plants of the family Aizoaceae are described. Plant cell gums of plants of the genus Mesembryanthemum are specifically provided. Also described are the methods of using these cultured plant cell gums in the manufacture of food products, pharmaceuticals and veterinary products, cosmetics and other industrial products, such as paper, adhesive, ink, textiles, paint, ceramics, explosives, cleaning agents or detergents, products for firefighting, agricultural chemicals including pesticides and fungicides, for oil and gas production, and in photography, lithography, and other industries are described. Food, pharmaceutical, veterinary, industrial and cosmetic compositions containing certain cultured plant cell gums are also described. Plant cell gums can be employed as substitutes for plant exudate and extract gums and other known emulsifying, viscosifying and gelling agents.
摘要翻译： 描述了某些培养的植物细胞树胶，包括在Aizoaceae植物植物的悬浮培养物中产生的那些。 专门提供植物细胞种子植物的植物细胞树胶。 还描述了使用这些培养的植物细胞胶在制造食品，药品和兽用产品，化妆品和其他工业产品如纸，粘合剂，油墨，纺织品，油漆，陶瓷，爆炸物，清洁剂或洗涤剂中的方法 ，消防产品，农药，杀菌剂等农药，油气生产，摄影，光刻等行业。 还描述了含有某些培养的植物细胞胶的食品，药物，兽医，工业和化妆品组合物。 植物细胞胶可用作植物渗出物的替代物并提取胶和其它已知的乳化，增粘和胶凝剂。
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3.发明授权公开(公告)号：US06261821B1
公开(公告)日：2001-07-17
申请号：US09431500
申请日：1999-11-01
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
IPC分类号： C12N950
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein the precursor comprises at least three PI monomers and wherein at least one of the monomers has a chymotrypsin specific site and at least one other of the monomers has a trypsin specific site.
摘要翻译： 本发明一般涉及蛋白酶抑制剂，其前体和编码它的遗传序列。 更具体地说，本发明涉及核酸分子，其包含编码或互补于编码来自植物的II型丝氨酸蛋白酶抑制剂（PI）前体的序列的核苷酸序列，其中所述前体包含至少三种PI单体和 其中所述单体中的至少一种具有糜蛋白酶特异性位点，并且所述单体中的至少一种具有胰蛋白酶特异性位点。
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4.发明授权
公开(公告)号：US6031087A
公开(公告)日：2000-02-29
申请号：US454295
申请日：1995-09-01
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
IPC分类号： A01H5/00 , C07H21/04 , C07K14/81 , C12N9/99 , C12N15/09 , C12N15/29 , C12P21/06 , C12Q1/68 , C12N5/04 , C12N9/50 , C12N9/76
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein said precursor comprises at least three PI monomers and wherein at least one of said monomers has a chymotrypsin specific site and at least one other of said monomers has a trypsin specific site.
摘要翻译： PCT No.PCT / AU93 / 00659 Sec。 371 1995年9月1日 102（e）1995年9月1日PCT PCT 1993年12月16日PCT公布。 WO94 / 13810PC公报。 日期：1994年6月23日本发明一般涉及蛋白酶抑制剂，其前体和编码其的遗传序列。 更具体地说，本发明涉及核酸分子，其包含编码或互补于编码来自植物的II型丝氨酸蛋白酶抑制剂（PI）前体的序列的核苷酸序列，其中所述前体包含至少三种PI单体和 其中所述单体中的至少一种具有糜蛋白酶特异性位点，所述单体中的至少一种具有胰蛋白酶特异性位点。
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公开(公告)号：US09175234B2
公开(公告)日：2015-11-03
申请号：US12645497
申请日：2009-12-23
申请人： Louis Hom , Na Trinh , Murtaza Alibhai , Zhihao Hu , Eli Groban , Vikranth Arlagadda , Elizabeth Clarke
发明人： Louis Hom , Na Trinh , Murtaza Alibhai , Zhihao Hu , Eli Groban , Vikranth Arlagadda , Elizabeth Clarke
摘要： The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of thioesterase enzymes. In particular, the present invention provides mutant thioesterase enzymes that have altered properties, for example, altered substrate specificity, altered activity, altered selectivity, and/or altered proportional yields in the product mixtures. The present invention also provides polynucleotides encoding such mutant thioesterase enzymes, and vectors and host cells comprising such polynucleotides. The invention further provides for novel uses of thioesterases in the production of various fatty acid derivatives, which are useful as, or as components of, industrial chemicals and fuels.
摘要翻译： 本发明涉及新的突变硫酯酶及其天然存在的等同物，由这些酶制成的组合物和硫酯酶的用途。 特别地，本发明提供突变体硫酯酶，其具有改变的性质，例如改变的底物特异性，改变的活性，改变的选择性和/或在产物混合物中改变的比例产率。 本发明还提供了编码这种突变体硫酯酶的多核苷酸，以及包含这种多核苷酸的载体和宿主细胞。 本发明进一步提供硫酯酶在生产各种脂肪酸衍生物中的新用途，其可用作或作为工业化学品和燃料的组分。
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6.发明授权公开(公告)号：US07410796B2
公开(公告)日：2008-08-12
申请号：US11598414
申请日：2006-11-13
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serin proteinase inhibitor (PI) precursor from a plant wherein the precursor comprises at least three PI monomers and wherein at least one of the monomers has a chymotrypsin specific site and at least one other of the monomers has a trypsin specific site.
摘要翻译： 本发明一般涉及蛋白酶抑制剂，其前体和编码它的遗传序列。 更具体地说，本发明涉及核酸分子，其包含编码或互补于编码来自植物的II型丝氨酸蛋白酶抑制剂（PI）前体的序列的核苷酸序列，其中所述前体包含至少三种PI单体和 其中所述单体中的至少一种具有糜蛋白酶特异性位点，并且所述单体中的至少一种具有胰蛋白酶特异性位点。
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7.发明授权公开(公告)号：US06955916B2
公开(公告)日：2005-10-18
申请号：US10164961
申请日：2002-06-07
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
IPC分类号： A01H5/00 , C07H21/04 , C07K14/81 , C12N9/99 , C12N15/09 , C12N15/29 , C12P21/06 , C12Q1/68 , C12N15/00 , C12N9/50 , C12N9/76
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein the precursor comprises at least three PI monomers and wherein at least one of the monomers has a chymotrypsin specific site and at least one other of the monomers has a trypsin specific site.
摘要翻译： 本发明一般涉及蛋白酶抑制剂，其前体和编码它的遗传序列。 更具体地说，本发明涉及核酸分子，其包含编码或互补于编码来自植物的II型丝氨酸蛋白酶抑制剂（PI）前体的序列的核苷酸序列，其中所述前体包含至少三种PI单体和 其中所述单体中的至少一种具有糜蛋白酶特异性位点，并且所述单体中的至少一种具有胰蛋白酶特异性位点。
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公开(公告)号：US06946278B2
公开(公告)日：2005-09-20
申请号：US10157622
申请日：2002-05-29
申请人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
发明人： Marilyn Anne Anderson , Angela Hilary Atkinson , Robyn Louise Heath , Adrienne Elizabeth Clarke
IPC分类号： A01H5/00 , C07H21/04 , C07K14/81 , C12N9/99 , C12N15/09 , C12N15/29 , C12P21/06 , C12Q1/68 , C12N9/76 , C12N9/50 , C12N15/00
CPC分类号： C07K14/811 , C12N2799/026 , C12N2799/06 , G01N2333/81 , G01N2500/02
摘要： The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein said precursor comprises at least three PI monomers and wherein at least one of said monomers has a chymotrypsin specific site and at least one other of said monomers has a trypsin specific site.
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9.发明授权Cultured plant cell gums for food, pharmaceutical, cosmetic and industrial applications 失效用于食品，制药，化妆品和工业应用的培养植物细胞胶公开(公告)号：US06271001B1
公开(公告)日：2001-08-07
申请号：US09072568
申请日：1998-05-05
IPC分类号： C12N500
CPC分类号： A61K8/73 , A61K8/99 , A61K9/0014 , A61K9/0019 , A61K47/36 , A61Q19/00 , C08B37/006 , C08L5/00 , C09D5/04 , C09D11/03 , C12P19/04
摘要： Certain cultured plant cell gums, including those produced in suspension culture of plant cells of plants of the family Aizoaceae are described. Plant cell gums of plants of the genus Mesembryanthemum are specifically provided. Also described are the methods of using these cultured plant cell gums in the manufacture of food products, pharmaceuticals and veterinary products, cosmetics and other industrial products, such as paper, adhesive, ink, textiles, paint, ceramics, explosives, cleaning agents or detergents, products for firefighting, agricultural chemicals including pesticides and fungicides, for oil and gas production, and in photography, lithography, and other industries are described. Food, pharmaceutical, veterinary, industrial and cosmetic compositions containing certain cultured plant cell gums are also described. Plant cell gums can be employed as substitutes for plant exudate and extract gums and other known emulsifying, viscosifying and gelling agents.
摘要翻译： 描述了某些培养的植物细胞树胶，包括在Aizoaceae植物植物的悬浮培养物中产生的那些。 专门提供植物细胞种子植物的植物细胞树胶。 还描述了使用这些培养的植物细胞胶在制造食品，药品和兽用产品，化妆品和其他工业产品如纸，粘合剂，油墨，纺织品，油漆，陶瓷，爆炸物，清洁剂或洗涤剂中的方法 ，消防产品，农药，杀菌剂等农药，油气生产，摄影，光刻等行业。 还描述了含有某些培养的植物细胞胶的食品，药物，兽医，工业和化妆品组合物。 植物细胞胶可用作植物渗出物的替代物并提取胶和其它已知的乳化，增粘和胶凝剂。
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10.发明授权Industrial pharmaceutical and cosmetics applications for cultured plant cell gums 失效用于培养植物细胞胶的工业制药和化妆品应用
公开(公告)号：US5747297A
公开(公告)日：1998-05-05
申请号：US409737
申请日：1995-03-23
IPC分类号： A61K8/73 , A61K8/99 , A61K9/00 , A61K47/36 , A61Q19/00 , B41N3/08 , C08B37/00 , C08L5/00 , C09D5/04 , C09D11/02 , C12P19/04 , C12P19/00 , C12N5/00
CPC分类号： C09D11/03 , A61K47/36 , A61K8/73 , A61K8/99 , A61K9/0014 , A61K9/0019 , A61Q19/00 , C08B37/006 , C08L5/00 , C09D5/04 , C12P19/04 , B41N3/08
摘要： Methods of using cultured plant cell gums in the paper, adhesive, oil and gas, ink, lithography, textile, paint, ceramics, cleaning detergent, cosmetics, photography, explosive, firefighting, agricultural, and other industries are described. Industrial and cosmetic compositions containing cultured plant cell gums are also described.
摘要翻译： 描述了在纸，粘合剂，油气，油墨，平版印刷，纺织品，油漆，陶瓷，清洁剂，化妆品，摄影，爆炸，消防，农业等行业中使用培养的植物细胞胶的方法。 还描述了含有培养的植物细胞胶的工业和化妆品组合物。
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