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12 条记录 (耗时 0.012 秒)

    METHODS FOR DIAGNOSIS OF AND PREDICTING TREATMENT EFFICACY OF HORMONE RECEPTOR EXPRESSING TUMORS, CANCERS AND NEOPLASIAS
    1.
    发明申请
    METHODS FOR DIAGNOSIS OF AND PREDICTING TREATMENT EFFICACY OF HORMONE RECEPTOR EXPRESSING TUMORS, CANCERS AND NEOPLASIAS 审中-公开
    用于诊断和预测激素受体表达肿瘤，癌症和神经细胞的治疗效果的方法

    公开(公告)号：US20110217702A1

    公开(公告)日：2011-09-08

    申请号：US12975058

    申请日：2010-12-21

    申请人： CAROLA LEUSCHNER ,  Hector Alila

    发明人： CAROLA LEUSCHNER ,  Hector Alila

    IPC分类号： C12Q1/68 ,  G01N33/566 ,  G01N33/53 ,  G01N33/574

    CPC分类号： C12Q1/68 ,  G01N33/53 ,  G01N33/566 ,  G01N33/574

    摘要： The invention relates to diagnosis, detection, screening, identifying and predicting methods. In various embodiments, methods of the invention include diagnosis, detection, or screening for a hyperproliferative disorder (e.g., a tumor, cancer or neoplasia) in the subject; identifying a subject that will or is likely to respond to a therapy for a hyperproliferative disorder (e.g., a tumor, cancer or neoplasia); and predicting therapeutic efficacy of a hyperproliferative disorder (e.g., a tumor, cancer or neoplasia) treatment in a subject.

    摘要翻译： 本发明涉及诊断，检测，筛选，鉴定和预测方法。 在各种实施方案中，本发明的方法包括对受试者中的过度增殖性疾病（例如肿瘤，癌症或瘤形成）的诊断，检测或筛选; 识别将会或可能对过度增殖性疾病（例如肿瘤，癌症或瘤形成）的治疗作出反应的对象; 并预测受试者中过度增殖性疾病（例如肿瘤，癌症或瘤形成）治疗的治疗功效。

    NUCLEOLIN-BINDING PEPTIDES, NUCLEOLIN- BINDING LYTIC PEPTIDES, FUSION CONSTRUCTS AND METHODS OF MAKING AND USING SAME
    8.
    发明申请
    NUCLEOLIN-BINDING PEPTIDES, NUCLEOLIN- BINDING LYTIC PEPTIDES, FUSION CONSTRUCTS AND METHODS OF MAKING AND USING SAME 审中-公开
    核蛋白结合肽，核蛋白结合胶原蛋白，融合构造及其制备和使用方法

    公开(公告)号：US20110124564A1

    公开(公告)日：2011-05-26

    申请号：US12868353

    申请日：2010-08-25

    申请人： Hector ALILA ,  Carola LEUSCHNER

    发明人： Hector ALILA ,  Carola LEUSCHNER

    IPC分类号： A61K38/10 ,  C07K7/06 ,  C07K7/08 ,  C07K14/00 ,  C07K19/00 ,  C07K16/18 ,  A61K38/08 ,  A61K38/02 ,  C12N5/071 ,  A61P35/00

    CPC分类号： C07K14/43563 ,  A61K38/00 ,  C07K14/4702 ,  C07K2319/30

    摘要： The invention relates to nucleolin binding peptides, nucleolin binding peptides and anti-nucleolin antibody conjugates with cytotoxic activity, fusion constructs, methods of using nucleolin binding peptides and antibodies and fusion constructs thereof, and methods of treating various disorders, undesirable conditions and diseases treatable with nucleolin binding peptides and fusion constructs, such as undesirable or aberrant cell proliferation (hyperproliferation) or hyperproliferative disorders, including tumors, cancers, neoplasia and malignancies, angiogenesis related or dependent diseases, and inflammatory diseases and inflammation.

    摘要翻译： 本发明涉及具有细胞毒活性的核仁林结合肽，核仁结合肽和抗核蛋白抗体缀合物，融合构建体，使用核仁核苷结合肽和抗体的方法及其融合构建体，以及治疗各种疾病，不良状况和可治疗的疾病的方法 核仁素结合肽和融合构建体，例如不期望的或异常的细胞增殖（过度增殖）或过度增殖性疾病，包括肿瘤，癌症，瘤形成和恶性肿瘤，血管发生相关或依赖性疾病，炎性疾病和炎症。