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公开(公告)号:US20110217318A1
公开(公告)日:2011-09-08
申请号:US13095098
申请日:2011-04-27
申请人: HIROSHI TAKAYAMA , KAMON SHIRAKAWA , SHOJI FURUSAKO , YOSHITAKA HOSAKA , TOMOKAZU MATSUSUE , KATSUKI NAITOH , YUMI HOTTA , TETSUSHI KAWAHARA , MOTOYASU HONDA
发明人: HIROSHI TAKAYAMA , KAMON SHIRAKAWA , SHOJI FURUSAKO , YOSHITAKA HOSAKA , TOMOKAZU MATSUSUE , KATSUKI NAITOH , YUMI HOTTA , TETSUSHI KAWAHARA , MOTOYASU HONDA
IPC分类号: A61K39/395 , C12N15/63 , C12N5/071 , C12P21/02 , C07K16/28 , C07H21/00 , A61P7/02 , C07K19/00
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/2803 , C07K16/34 , C07K2317/24 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30
摘要: The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
摘要翻译: 本发明提供具有以下特征的抗体,其活性片段或其衍生物:a)其特异性结合人血小板膜糖蛋白VI(GPVI); b)激活血小板和/或在体内诱导血小板减少症的功能低; 和c)它通过与血小板接触至少部分地消耗血小板膜上的GPVI。
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公开(公告)号:US20090041783A1
公开(公告)日:2009-02-12
申请号:US11816233
申请日:2006-01-27
申请人: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara
发明人: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara
IPC分类号: A61K39/395 , C07K16/18 , C12N5/06 , C07K14/00 , A61P43/00 , G01N33/566 , C12N15/11 , C12P21/04
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/2803 , C07K16/34 , C07K2317/24 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30
摘要: The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
摘要翻译: 本发明提供具有以下特征的抗体,其活性片段或其衍生物:a)其特异性结合人血小板膜糖蛋白VI(GPVI); b)激活血小板和/或在体内诱导血小板减少症的功能低; 和c)它通过与血小板接触至少部分地消耗血小板膜上的GPVI。
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公开(公告)号:US06259875B1
公开(公告)日:2001-07-10
申请号:US09373208
申请日:1999-08-12
IPC分类号: B03B1502
CPC分类号: G03G15/0233 , Y10T428/25
摘要: A charging member has a conductive core, a conductive elastic layer formed on the surface of the conductive core, and a wearing surface layer to be used also as a resistance controlling layer formed on the surface of the conductive elastic layer, and comprising a surface layer-forming resin and a resistance controlling conductive filler, developing conductivity by electron conduction and having a specific wearing amount of 5.0×10−4 (mm3/N·km) or more, the charging member capable of preventing deterioration of the charging performance of a charging member caused by contamination of the surface layer of the charging member, and maintaining stable and satisfactory uniform charging property and image quality for a long period of time, and always keeping the surface clean by positively wearing the surface layer of the charging member.
摘要翻译: 充电构件具有导电芯,形成在导电芯的表面上的导电弹性层和用作形成在导电弹性层的表面上的电阻控制层的磨损表面层,并且包括表面层 形成树脂和电阻控制导电填料,通过电子传导显影导电性,并且具有5.0×10 -4(mm 3 / N.km)以上的特定磨损量,该充电构件能够防止充电的充电性能的劣化 由充电构件的表面层的污染引起的构件,并且长时间保持稳定和令人满意的均匀充电性能和图像质量,并且通过正面地佩戴充电构件的表面层来始终保持表面清洁。
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公开(公告)号:US6134408A
公开(公告)日:2000-10-17
申请号:US386443
申请日:1999-08-31
CPC分类号: G03G15/0233
摘要: The invention is to suppress a fluctuation in resistance of a charging member due to the environment and the applied voltage, and to suppress the charging potential of a photosensitive article to realize uniformity in charging by preventing generation of leakage at a part of a low resistance on the surface of the photosensitive article. The charging member may have a conductive core material, a conductive elastic layer formed on a surface of the conductive core material, and a resistance adjusting layer for adjusting a resistance between the conductive core material and the surface of the article to be charged, formed on a surface of the conductive core material, have a material for forming the resistance adjusting layer and a conductive filler for adjusting resistance that exhibits conductivity by electronic conduction, and having a volume resistivity of 5.times.10.sup.5 .OMEGA..multidot.cm or more at an electric field of 5.times.10.sup.4 V/cm.
摘要翻译: 本发明是为了抑制由于环境和施加电压引起的充电部件的电阻波动,并且通过防止在低电阻部分产生泄漏来抑制感光制品的充电电位,从而实现充电均匀性 感光制品的表面。 充电构件可以具有导电芯材,形成在导电芯材的表面上的导电弹性层和用于调节导电芯材与待充电制品表面之间的电阻的电阻调节层,形成在 导电芯材的表面具有用于形成电阻调节层的材料和用于调节通过电子传导显示导电性的电阻的导电填料,并且在5×10 4 V / cm 2的电场下具有5×10 5欧姆×xcm以上的体积电阻率, 厘米。
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公开(公告)号:US5631043A
公开(公告)日:1997-05-20
申请号:US452369
申请日:1995-05-26
申请人: Kenji Ogi , Hiroshi Takayama , Yasuo Yamamoto , Kazuo Maruyama , Eiichi Akutsu
发明人: Kenji Ogi , Hiroshi Takayama , Yasuo Yamamoto , Kazuo Maruyama , Eiichi Akutsu
CPC分类号: B41J2/325 , G03G15/344 , Y10S428/913 , Y10S428/914 , Y10T428/24802 , Y10T428/24901 , Y10T428/25 , Y10T428/254 , Y10T428/31504 , Y10T428/31786
摘要: An ink transfer medium for toner is disclosed, comprising the following layers, in this order: a heat-generating resistive layer heated by input of electrical signal, a conductive layer, and an ink release layer having a toner layer on it, an adhesion from 0.2 g/mm to 40 g/mm as measured by the 90.degree. peeling off method and consisting of a viscoelastomer having a critical surface tension of 35 dyne/cm or less. It can be re-inked by attaching toner to the portions of the ink transfer medium from which the ink has been removed, using toner held in a toner holding means.An ink transfer process for toner is also disclosed, wherein an ink transfer medium having toner layer formed on the above described ink release layer is used and the toner layer contacts the recording medium under pressure, while a recording head contacts the anisotropic conductive layer of the ink transfer medium, so that an electrical signal is input and then toner fused by heat generated by the heat-generating resistive layer is transferred to the recording medium.
摘要翻译: 公开了一种用于调色剂的油墨转印介质,包括以下层:通过电信号输入加热的发热电阻层,导电层和在其上具有调色剂层的油墨释放层, 0.2g / mm至40g / mm,通过90°剥离法测量,并由粘弹性体组成,其临界表面张力为35达因/厘米或更小。 通过使用保持在调色剂保持装置中的调色剂将调色剂附着到已经从中除去油墨的油墨转印介质的部分上,可以再次进行再墨。 还公开了一种用于调色剂的油墨转印方法,其中使用在上述油墨释放层上形成有调色剂层的油墨转印介质,并且调色剂层在压力下与记录介质接触,而记录头接触到 油墨转印介质,从而输入电信号,然后通过发热电阻层产生的热量将调色剂转印到记录介质上。
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公开(公告)号:US5250996A
公开(公告)日:1993-10-05
申请号:US882136
申请日:1992-05-13
申请人: Yutaka Sugizaki , Hiroshi Takayama , Hideyuki Akagi , Takashi Imai , Susumu Saito , Yoshio Shoji , Yasuhiro Uehara , Masanori Ichimura , Tomohiro Ohkawa , Manabu Serizawa , Yasuo Yamamoto , Michio Take , Satoshi Inoue
发明人: Yutaka Sugizaki , Hiroshi Takayama , Hideyuki Akagi , Takashi Imai , Susumu Saito , Yoshio Shoji , Yasuhiro Uehara , Masanori Ichimura , Tomohiro Ohkawa , Manabu Serizawa , Yasuo Yamamoto , Michio Take , Satoshi Inoue
CPC分类号: G03G9/08755 , G03G13/20 , G03G15/0105 , G03G15/2025
摘要: A method for fixing a full color toner image by inserting a transfer medium to which a toner image is transferred, between a pair of rolls of a fixing apparatus, and pressing the medium therebetween, wherein the toner image is formed of a full color toner prepared by dispersing a colorant into a polyester resin containing a diol component represented by the following general formula (I) as a constituent and having a softening point of 100.degree. to 120.degree. C., as measured by a ring and ball method, a glass transition temperature of 55.degree. C. or more, a Gardner color scale of 2 or less and a haze value of 15 or less, and the fixing operation is conducted while supplying a functional group-containing organopolysiloxane having a viscosity of 10 to 100,000 cs at 25.degree. C. to a roll in contact with the toner image, whereby the full color toner image can be stably fixed without wrapping of the transfer medium around the roll and offset, and the fixed image having good image quality can be obtained: ##STR1## wherein R represents an ethylene group or a propylene group, each of x and y is an integer of 1 or more, and x+y is 2 to 6.
摘要翻译: 一种通过将定影设备的一对辊之间插入转印有调色剂图像的转印介质并在其间按压介质来固定全色调色剂图像的方法,其中调色剂图像由全色调色剂形成 通过将着色剂分散在含有由以下通式(I)表示的二醇组分的聚酯树脂中作为组分,并且通过环球法测量的软化点为100-120℃,玻璃化转变 温度为55℃以上,Gardner色标为2以下,雾度值为15以下,进行定影操作,同时在25℃下提供粘度为10〜100,000cs的含官能团的有机聚硅氧烷 使其与调色剂图像接触,从而可以稳定地固定全色调色剂图像,而不会在辊周围缠绕转印介质并且偏移,并且可以获得具有良好图像质量的固定图像 (I)其中R表示亚乙基或亚丙基,x和y各自为1以上的整数,x + y为2〜6。
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公开(公告)号:US4264698A
公开(公告)日:1981-04-28
申请号:US732759
申请日:1976-10-15
申请人: Hiroshi Takayama , Tatsuo Aizawa
发明人: Hiroshi Takayama , Tatsuo Aizawa
CPC分类号: G03G9/0837 , G03G9/0904 , G03G9/10 , Y10T428/2998
摘要: A developer for electrostatic photography consisting essentially of a dry blend of (A) substantially spherical fixing magneto-sensitive particles of a composition comprising a binder medium and a fine powder of a magnetic material dispersed in the binder medium, the substantially spherical particles (A) have on their surfaces fine convexities and concavities formed by spraying a dispersion of the composition into a drying atmosphere and have a particle size of 2 to 44 microns, and (B) flowability- and electric resistance-controlling fine particles having a volume resistivity not higher than 10.sup.12 .omega.-cm and a particle size not larger than 1/10 of the particle size of the substantially spherical particles (A). The fine particles (B) are distributed predominantly on the surface portion of said spherical particles (A). The mixing weight ratio of (A):(B) is in the range of from 1000:1 to 50:1.
摘要翻译: 用于静电摄影的显影剂,其基本上由(A)基本上球形的包含粘合剂介质的组合物的固体感磁性颗粒和分散在粘合剂介质中的磁性材料的细粉末的干混合物组成,基本上为球形的颗粒(A) 在其表面上具有通过将组合物的分散体喷雾到干燥气氛中并具有2至44微米的粒度而形成的细小的凸起和凹陷,以及(B)体积电阻率不高的流动性和电阻控制微粒 大于1012Ω·cm,粒径不大于基本上球形颗粒(A)的粒度的1/10。 细颗粒(B)主要分布在所述球形颗粒(A)的表面部分上。 (A):(B)的混合重量比在1000:1〜50:1的范围内。
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公开(公告)号:US07977461B2
公开(公告)日:2011-07-12
申请号:US11912757
申请日:2006-04-28
申请人: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara , Motoyasu Honda
发明人: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara , Motoyasu Honda
IPC分类号: C12P21/08
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/2803 , C07K16/34 , C07K2317/24 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30
摘要: The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
摘要翻译: 本发明提供具有以下特征的抗体,其活性片段或其衍生物:a)其特异性结合人血小板膜糖蛋白VI(GPVI); b)激活血小板和/或在体内诱导血小板减少症的功能低; 和c)它通过与血小板接触至少部分地消耗血小板膜上的GPVI。
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公开(公告)号:US6148660A
公开(公告)日:2000-11-21
申请号:US160396
申请日:1998-09-25
申请人: Randolph Kwok-Kin Chiu , Charles Dale Oakley , Russell Harmon Bosch , Magnus Glavmo , Hiroshi Takayama , Keisuke Okajima
发明人: Randolph Kwok-Kin Chiu , Charles Dale Oakley , Russell Harmon Bosch , Magnus Glavmo , Hiroshi Takayama , Keisuke Okajima
CPC分类号: F02P19/028 , F23Q7/001 , F23Q2007/002
摘要: A glow sensor which combines functions of a diesel engine glow plug with an ion sensor for sensing engine combustion initiation and characteristics includes a ceramic rod retained in a supporting ceramic sleeve carried by a metal shell mountable in an engine cylinder head. The ceramic rod includes a heating element in a glow tip at the inner end of the rod which, in use, extends into an engine combustion chamber or pre-chamber. A conductive material such as platinum or palladium is coated on the lower end of the glow tip and connected by a conductor with a source of electric voltage. In use, the voltage produces a current carried by electrons generated by ionization of the combustion chamber gases during combustion. The current varies with the degree of ionization and the amount of electrons generated during various phases of the combustion event. The resulting information is usable in controlling engine operation or evaluating its operation for test purposes. Various construction features of disclosed embodiments include an internal conductor through the ceramic rod from the platinum or palladium material to a lead or an external conductor applied on the surface of the ceramic rod with which an insulating ceramic sleeve is utilized to mount the rod within its supporting shell. Grounding connections through an additional lead from the outer end of the ceramic rod or via metallic connections through the ceramic sleeve to the shell are alternatively disclosed.
摘要翻译: 将柴油发动机预热塞与用于感测发动机燃烧起动和特性的离子传感器的功能组合的辉光传感器包括保持在由可安装在发动机气缸盖中的金属壳承载的支撑陶瓷套筒中的陶瓷棒。 陶瓷棒包括在杆的内端处的辉光尖端中的加热元件,其在使用中延伸到发动机燃烧室或预制室中。 诸如铂或钯的导电材料涂覆在辉光尖端的下端,并由具有电压源的导体连接。 在使用中,电压产生由燃烧室内的燃烧室气体的电离产生的电子携带的电流。 电流随着电离的程度和在燃烧事件的各个阶段期间产生的电子的量而变化。 所得到的信息可用于控制发动机操作或评估其操作用于测试目的。 所公开的实施例的各种结构特征包括通过陶瓷棒从铂或钯材料到引线或外部导体的内部导体,该导体或外部导体施加在陶瓷棒的表面上,通过该导体或外部导体使用绝缘陶瓷套管将杆安装在其支撑 贝壳。 可选地公开了通过陶瓷棒的外端的附加引线或经由穿过陶瓷套管的金属连接到壳体的接地连接。
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公开(公告)号:US5897477A
公开(公告)日:1999-04-27
申请号:US806931
申请日:1997-02-26
申请人: Kenji Nakatogawa , Shigeo Ohta , Hiroshi Takayama
发明人: Kenji Nakatogawa , Shigeo Ohta , Hiroshi Takayama
CPC分类号: G03G15/0928
摘要: A developer carrier comprising a cylindrical support having provided on the outer surface thereof a coating layer for retaining a developer, wherein the coating layer comprises electrically conductive fine particles and a binder resin comprising a phenolic resin having a weight-average molecular weight of from 3,000 to 5,000 as determined before being crosslinked. Also disclosed is a developing apparatus which comprises a developer carrier for retaining a developer on the surface thereof and for conveying the developer onto the position at which an electrostatic latent image formed on a latent image carrier is developed, wherein the developer carrier comprises a cylindrical support having provided on the outer surface thereof a coating layer for retaining a developer, wherein the coating layer comprises electrically conductive fine particles and a binder resin comprising a phenolic resin having a weight-average molecular weight of from 3,000 to 5,000 as determined before being crosslinked.
摘要翻译: 一种显影剂载体,其包括在其外表面上设置有用于保持显影剂的涂层的圆柱形支撑体,其中所述涂层包含导电细颗粒和包含酚醛树脂的粘合剂树脂,所述酚醛树脂的重均分子量为3,000至 交联前测定的5,000。 还公开了一种显影装置,其包括用于将显影剂保持在其表面上并用于将显影剂输送到形成在潜像载体上的静电潜像显影的位置的显影剂载体,其中显影剂载体包括圆柱形支撑体 在其外表面上设置有用于保持显影剂的涂层,其中所述涂层包含导电细颗粒和包含在交联之前测定的重均分子量为3,000至5,000的酚醛树脂的粘合剂树脂。
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