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公开(公告)号：US06465514B1
公开(公告)日：2002-10-15
申请号：US09696831
申请日：2000-10-26
IPC分类号： A61K3124
CPC分类号： A61K8/63 , A61K8/445 , A61K8/4953 , A61K31/24 , A61K31/44 , A61K31/505 , A61K45/06 , A61Q7/00 , A61K2300/00
摘要： Compositions, medicaments, and methods for the promotion of hair growth are disclosed. These compositions and medicaments are comprised of either local anesthetics of the secondary or tertiary amino type and/or niacin. The preferred secondary and tertiary amino compounds include those which are esters of para-aminobenzoic acid, esters of benzoic acid, esters of meta-amino benzoic acid, amides, ethers, and ketones. The preferred compositions and medicaments include either procaine hydrochloride or niacin or procaine hydrochloride and niacin in a non-sulfur-containing carrier. The disclosed compositions and medicaments may be topically applied to a scalp in need thereof by an eyedropper or other suitable means. An improved embodiment of this application adds minoxidil. Another improved embodiment administers Propecia™ orally while the anesthetic (e.g., procaine hydrochloride) and niacin are administered topically.
摘要翻译： 公开了用于促进头发生长的组合物，药物和方法。 这些组合物和药物由二级或叔氨基型和/或烟酸的局部麻醉剂组成。 优选的仲氨基和叔氨基化合物包括那些是对氨基苯甲酸的酯，苯甲酸的酯，间氨基苯甲酸的酯，酰胺，醚和酮的那些。 优选的组合物和药物包括盐酸普鲁卡因或烟酸或盐酸普鲁卡因和含硫载体中的烟酸。 所公开的组合物和药物可以通过吸管或其它合适的方式局部施用于有需要的头皮。 该应用的改进的实施方案添加了米诺地尔。 另一改进的实施方案口服施用Propecia TM，同时局部施用麻醉剂（例如盐酸普鲁卡因）和烟酸。
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公开(公告)号：US5777717A
公开(公告)日：1998-07-07
申请号：US593880
申请日：1996-01-30
申请人： Neil F. Martin , Howard N. Robinson
发明人： Neil F. Martin , Howard N. Robinson
CPC分类号： G02C5/001 , A61F9/00 , G02C7/02 , G02C7/04 , G02C7/048 , G02C7/104 , G02C7/105 , G02C7/16 , A61F9/0136
摘要： Contact lenses with contoured anterior surfaces are employed to obtain informed consent from a patient prior to ophthalmic surgery. These modified contact lenses with contoured surfaces, when worn by a patient, will mimic visual distortions which might result from various types of corneal surgery.
摘要翻译： 在眼科手术之前，使用具有轮廓前表面的隐形眼镜获得患者的知情同意。 具有轮廓表面的这些修改后的隐形眼镜在被患者佩戴时将模仿可能由各种类型的角膜手术引起的视觉扭曲。
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公开(公告)号：US5737056A
公开(公告)日：1998-04-07
申请号：US593879
申请日：1996-01-30
CPC分类号： G02C5/001 , A61F9/00 , G02C7/02 , G02C7/04 , G02C7/048 , G02C7/104 , G02C7/105 , G02C7/16 , A61F9/0136
摘要： The disclosed invention is directed to lenses to be worn with eyeglasses. The light transmission or field of vision of the lenses has been so modified as to produce visual distortions simulating various eye conditions and particularly simulated possible postoperative visual distortions and anomalies. Various modifications to conventional eyeglasses are disclosed.
摘要翻译： 所公开的发明涉及要戴眼镜的镜片。 镜片的光透射或视野已经被修改，以产生模拟各种眼睛状况的视觉变形，特别是模拟可能的术后视觉失真和异常。 公开了对常规眼镜的各种修改。
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公开(公告)号：US5614545A
公开(公告)日：1997-03-25
申请号：US477089
申请日：1995-06-07
申请人： Neil F. Martin , Howard N. Robinson
发明人： Neil F. Martin , Howard N. Robinson
IPC分类号： A61K9/00 , A61K31/415 , A61K31/535
CPC分类号： A61K31/415 , A61K9/0048
摘要： A pharmaceutical composition for treating blepharitis or blepharoconjunctivitis is disclosed for topical administration comprising a nitroimidazole, as metronidazole, in a suitable ophthalmic carrier to be applied directly to affected ocular tissues. The carrier may be an artificial tear solution, an ointment, a water soluble gel, a nonaqueous carrier or an eyelash shampoo.
摘要翻译： 公开了一种用于治疗睑炎或眼结膜炎的药物组合物，用于局部给药，其包括硝基咪唑作为甲硝唑，在适合的眼科载体中直接施用于受影响的眼组织。 载体可以是人造泪液，软膏，水溶性凝胶，非水性载体或睫毛洗发剂。
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5.发明授权
公开(公告)号：US5515872A
公开(公告)日：1996-05-14
申请号：US320858
申请日：1994-10-11
申请人： Neil F. Martin , Howard N. Robinson
发明人： Neil F. Martin , Howard N. Robinson
IPC分类号： A61B17/122 , A61F9/00 , A61F9/007 , A61B19/00
CPC分类号： A61B17/1227 , A61F9/0008 , A61F9/0026 , A61F9/00772
摘要： The invention herein described involves a clamp placed over the bridge of the nose to apply pressure over the fossa of the nasolacrimal sac, prior to ocular medication, to seal the nasolacrimal sac, and thereby prevent drainage of medicament away from the eye.
摘要翻译： 本文所述的发明涉及一种放置在鼻梁上方的夹具，以在眼药物之前施加压在鼻泪囊上的压力，以密封鼻泪囊，从而防止药物从眼睛排出。
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公开(公告)号：US5260292A
公开(公告)日：1993-11-09
申请号：US883914
申请日：1992-05-12
申请人： Howard N. Robinson , Neil F. Martin
发明人： Howard N. Robinson , Neil F. Martin
IPC分类号： A61K9/00 , A61K31/43 , A61K31/545 , A61K47/10
CPC分类号： A61Q19/00 , A61K31/43 , A61K31/545 , A61K47/10 , A61K8/49 , A61K9/0014 , Y10S514/859 , Y10S514/944
摘要： A method and composition for topically treating acne and acneiform dermal disorders includes applying an amount of an antibiotic selected from the group consisting of ampicillin, amoxicillin, other aminopenicillins, and cephalosporin, and derivatives and analogs thereof, effective to treat the acne and acneiform dermal disorders. The antibiotic is blended with a carrier suitable for topical application to dermal tissues. The carrier is selected from the group consisting of an aqueous liquid, an alcohol base, a water soluble gel, a lotion, an ointment base, petrolatum, a nonaqueous liquid base, a mineral oil base, a blend of mineral oil and petrolatum, a suspension of solid particles in a liquid, and a suspension of an ion-exchange resin in water.
摘要翻译： 用于局部治疗痤疮和粉刺性皮肤病症的方法和组合物包括施用一定量的选自氨苄青霉素，阿莫西林，其他氨基青霉素和头孢菌素的抗生素及其衍生物和类似物，其有效治疗痤疮和粉刺性皮肤病 。 将抗生素与适于局部施用于真皮组织的载体混合。 载体选自水性液体，醇碱，水溶性凝胶，洗剂，软膏剂，凡士林，非水性液体碱，矿物油基质，矿物油和凡士林的混合物， 将液体中的固体颗粒悬浮，以及离子交换树脂在水中的悬浮液。
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公开(公告)号：US06344335B1
公开(公告)日：2002-02-05
申请号：US09280985
申请日：1999-05-27
IPC分类号： G01N33536
CPC分类号： G01N33/586 , G01N33/725 , Y02A50/55 , Y02A50/56 , Y02A50/57 , Y02A50/59 , Y10T428/2984
摘要： A liposome or microsphere containing guaiac or other reagent is used in an immunoassay to detect an antigen or antibody. The guaiac or other reagent reacts with hemoglobin or other blood constituent to produce color indicating a positive result.
摘要翻译： 在免疫测定中使用含有愈创木酚或其他试剂的脂质体或微球以检测抗原或抗体。 愈创木酮或其他试剂与血红蛋白或其他血液成分反应产生表明阳性结果的颜色。
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公开(公告)号：US06300140B1
公开(公告)日：2001-10-09
申请号：US09348524
申请日：1999-07-07
IPC分类号： G01N33543
CPC分类号： B01L3/508 , A61B10/02 , B01L2300/043 , B01L2300/0822 , C12Q1/24 , G01N33/54386 , G01N33/56961 , Y10S435/921 , Y10S435/922 , Y10S435/923 , Y10S435/924 , Y10S435/962 , Y10S435/97 , Y10S435/973 , Y10S436/809 , Y10S436/81
摘要： A slide having a portion thereof provided with transparent adhesive which adheres to a test sample. The slide and adhesive may be transparent. Specific types of infection and particularly fungal infections can be detected in the test sample using immunotest-methods. In a special embodiment the adhesive slide is fashioned with a peripheral lip or well to contain a test sample and a reagent.
摘要翻译： 具有其一部分的滑块，其具有粘附到测试样品的透明粘合剂。 滑块和粘合剂可以是透明的。 可以使用免疫测定法在测试样品中检测特定类型的感染，特别是真菌感染。 在一个特殊的实施方案中，粘合剂载片与外围唇缘或孔一起形成以容纳测试样品和试剂。
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9.发明授权Low potency unpreserved sterile topical corticosteroid compositions for dermatitis 失效低效率无保护的无菌局部皮质类固醇组合物用于皮炎公开(公告)号：US06395721B1
公开(公告)日：2002-05-28
申请号：US09477838
申请日：2000-01-05
申请人： Howard N. Robinson , Neil F. Martin
发明人： Howard N. Robinson , Neil F. Martin
IPC分类号： A61K3156
CPC分类号： A61K31/565 , A61K9/0014 , A61K9/0048 , A61K31/573 , A61K31/58 , A61K47/06 , A61K47/44 , Y10S514/912
摘要： Low potency, preservative free sterile topical anti-inflammatory steroid compositions are to be applied to the area surrounding the eye. The compositions involve, for example, sterile gauze pads in a sterile package, as well as single-use capsules and tubes for dispensing the medicinal composition.
摘要翻译： 低效能，无防腐剂的无菌局部抗炎类固醇组合物应用于眼周围区域。 组合物涉及例如无菌包装中的无菌纱布垫，以及用于分配药物组合物的一次性胶囊和管。
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公开(公告)号：US5919633A
公开(公告)日：1999-07-06
申请号：US951214
申请日：1997-09-19
IPC分类号： G01N33/58 , G01N33/72 , G01N33/53 , G01N33/571
CPC分类号： G01N33/586 , G01N33/725
摘要： A liposome or microsphere containing guaiac or other reagent is used in an immunoassay to detect an antigen or antibody. The guaiac or other reagent reacts with hemoglobin or other blood constituent to produce color indicating a positive result.
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