公开(公告)号：US08420349B2

公开(公告)日：2013-04-16

申请号：US12668533

申请日：2008-07-11

Applicant: Jaroslav A. Kralovec ,  Weijie Wang ,  Colin James Barrow

Inventor： Jaroslav A. Kralovec ,  Weijie Wang ,  Colin James Barrow

IPC: C12P1/00 ,  C12P7/64 ,  C12P7/62

CPC classification number: C12P7/6409 ,  C11C1/045 ,  C12P7/6418 ,  C12P7/6445 ,  C12P7/6472 ,  C12P7/649 ,  Y02E50/13

Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.

Abstract translation: 所公开的主题一般涉及用于改性油的方法，具体涉及提高油组合物中多不饱和脂肪酸浓度的方法。

公开(公告)号：US20110117180A1

公开(公告)日：2011-05-19

申请号：US12522826

申请日：2008-01-09

Applicant: Cuie Yan ,  Wei Zhang ,  Yulai Jin ,  Lesek Alexa Demont ,  Colin James Barrow

Inventor： Cuie Yan ,  Wei Zhang ,  Yulai Jin ,  Lesek Alexa Demont ,  Colin James Barrow

IPC: A61K9/127 ,  A61K9/66 ,  A61K35/12 ,  A61K36/06 ,  A61K36/02 ,  A61K36/00 ,  A61K35/66 ,  A61K31/202 ,  A61K31/22 ,  A61K31/56 ,  A61K38/17 ,  A61K31/715 ,  A61K31/6615 ,  A61P1/00 ,  A61P3/02 ,  A23L1/00 ,  A23L1/30 ,  A23L2/38

CPC classification number: A61K9/5089 ,  A23L33/115 ,  A23L33/12 ,  A23P10/30 ,  A61K8/11 ,  A61K8/64 ,  A61K8/645 ,  A61K8/65 ,  A61K8/73 ,  A61K8/733 ,  A61K9/5036 ,  A61K9/5052 ,  A61K9/5057 ,  A61K9/5073 ,  A61K2800/412 ,  A61Q19/00

Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.

Abstract translation: 公开了具有不是动物副产物的壳的微胶囊和用于制备和使用这种微胶囊的方法。

公开(公告)号：US07691388B2

公开(公告)日：2010-04-06

申请号：US11388574

申请日：2006-03-24

Applicant: Harry Stephen Ewart ,  Junzeng Zhang ,  Colin James Barrow

Inventor： Harry Stephen Ewart ,  Junzeng Zhang ,  Colin James Barrow

IPC: A61K35/80

CPC classification number: A01G33/00 ,  A23L17/60 ,  A23L33/17 ,  A23V2002/00 ,  A61K36/04 ,  A23V2250/708 ,  A23V2250/704 ,  A23V2250/156 ,  A23V2250/06 ,  A23V2250/202 ,  A23V2250/211

Abstract: Disclosed herein are compositions comprising Porphyra, as well as methods of making and using such compositions.

Abstract translation: 本文公开了包含紫菜的组合物，以及制备和使用这些组合物的方法。

公开(公告)号：US20080015233A1

公开(公告)日：2008-01-17

申请号：US11547994

申请日：2005-04-20

Applicant: James Barrow ,  Georgia McGaughey ,  Philippe Nantermet ,  Hemaka Rajapakse ,  Harold Selnick ,  Shaun Stauffer ,  Joseph Vacca ,  Shawn Stachel ,  Craig Coburn ,  Matthew Stanton

Inventor： James Barrow ,  Georgia McGaughey ,  Philippe Nantermet ,  Hemaka Rajapakse ,  Harold Selnick ,  Shaun Stauffer ,  Joseph Vacca ,  Shawn Stachel ,  Craig Coburn ,  Matthew Stanton

IPC: A61K31/4439 ,  A61P25/28 ,  C07D401/04 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04

CPC classification number: C07D413/04 ,  C07D401/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14

Abstract: The present invention is directed to 2,4,6-substituted pyridyl derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

Abstract translation: 本发明涉及作为β-分泌酶的抑制剂并可用于治疗其中涉及β-分泌酶的疾病如阿尔茨海默氏病的2,4,6-取代的吡啶衍生物化合物。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

公开(公告)号：US20070197571A1

公开(公告)日：2007-08-23

申请号：US11663388

申请日：2005-10-12

Applicant: James Barrow ,  Craig Coburn ,  Melissa Egbertson ,  Georgia McGaughey ,  Melody McWherter ,  Lou Neilson ,  Kenneth Rittle ,  Harold Selnick ,  Shaun Stauffer ,  Zhi-Qiang Yang ,  Wenjin Yang ,  Wanli Lu ,  Bruce Fahr

Inventor： James Barrow ,  Craig Coburn ,  Melissa Egbertson ,  Georgia McGaughey ,  Melody McWherter ,  Lou Neilson ,  Kenneth Rittle ,  Harold Selnick ,  Shaun Stauffer ,  Zhi-Qiang Yang ,  Wenjin Yang ,  Wanli Lu ,  Bruce Fahr

IPC: A61K31/4747 ,  C07D471/10

CPC classification number: C07D471/10

Abstract: The present invention is directed to spiropiperidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

Abstract translation: 本发明涉及作为β-分泌酶的抑制剂并且可用于治疗其中涉及β-分泌酶的疾病如阿尔茨海默氏病的式（I）的哌啶哌啶化合物。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

公开(公告)号：US20070142634A1

公开(公告)日：2007-06-21

申请号：US10582856

申请日：2004-12-15

Applicant: James Barrow ,  Craig Coburn ,  Philippe Nantermet ,  Harold Selnick ,  Shawn Stachel ,  Matthew Stanton ,  Shaun Stauffer ,  Linghang Zhuang ,  Jennifer Davis

Inventor： James Barrow ,  Craig Coburn ,  Philippe Nantermet ,  Harold Selnick ,  Shawn Stachel ,  Matthew Stanton ,  Shaun Stauffer ,  Linghang Zhuang ,  Jennifer Davis

IPC: A61K31/5377 ,  C07D417/02 ,  C07D413/02 ,  C07D403/02 ,  C07D213/72

CPC classification number: C07D213/81 ,  C07D213/75 ,  C07D257/04 ,  C07D401/04 ,  C07D409/12 ,  C07D413/12

Abstract: The present invention is directed to phenylamide and pyridylamide derivative compounds of which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

Abstract translation: 本发明涉及苯酰胺和吡啶酰胺衍生物化合物，其是β-分泌酶的抑制剂，可用于治疗其中涉及β-分泌酶的疾病，例如阿尔茨海默氏病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

公开(公告)号：US872042A

公开(公告)日：1907-11-26

申请号：US1906338015

申请日：1906-10-08

Applicant: JOSEPH JAMES BARROW

Inventor： KING THOMAS JOEL

CPC classification number: G09F11/29

公开(公告)号：US09056058B2

公开(公告)日：2015-06-16

申请号：US12308045

申请日：2007-06-04

Applicant: Jin Yulai ,  Colin James Barrow ,  Wei Zhang ,  Cuie Yan ,  Jonathan Michael Curtis ,  Shawn Moulton ,  Nancy Beatrice Djogbenou ,  Lesek Alexa Demont

Inventor： Jin Yulai ,  Colin James Barrow ,  Wei Zhang ,  Cuie Yan ,  Jonathan Michael Curtis ,  Shawn Moulton ,  Nancy Beatrice Djogbenou ,  Lesek Alexa Demont

IPC: A61K31/575 ,  A61P35/00 ,  A61P37/08 ,  A61P9/02 ,  A61K9/16 ,  A61P9/10 ,  A61K31/202 ,  A61P9/00 ,  A61K31/232 ,  A61K9/50 ,  A23L1/00 ,  A23L1/30 ,  A23L1/304 ,  A23L1/305

CPC classification number: A61K9/5057 ,  A23L33/10 ,  A23L33/105 ,  A23L33/115 ,  A23L33/16 ,  A23L33/19 ,  A23P10/30 ,  A23V2002/00 ,  A61K9/1658 ,  A23V2250/54252 ,  A23V2250/1868 ,  A23V2200/224 ,  A23V2250/187 ,  A23V2250/1642

Abstract: Disclosed are microcapsules and methods for preparing and using them, as well as methods for improving various properties of microcapsules like impermeability.

Abstract translation: 公开了用于制备和使用它们的微胶囊和方法，以及用于改善微胶囊如不渗透性的各种性质的方法。

公开(公告)号：US08921069B2

公开(公告)日：2014-12-30

申请号：US13427562

申请日：2012-03-22

Applicant: Adam M. Burja ,  Helia Radianingtyas ,  Colin James Barrow ,  Anthony James Windust

Inventor： Adam M. Burja ,  Helia Radianingtyas ,  Colin James Barrow ,  Anthony James Windust

IPC: C12P1/00 ,  C12P7/64 ,  A21D8/04 ,  A23K1/00 ,  A23K1/16 ,  A23L1/00 ,  A23L1/03 ,  A23L1/30 ,  A61K9/48 ,  A61K31/20

CPC classification number: C12P7/6427 ,  A21D8/04 ,  A23K10/18 ,  A23K20/158 ,  A23L29/065 ,  A23L33/115 ,  A23L33/12 ,  A23L33/135 ,  A23P10/30 ,  A23V2002/00 ,  A61K9/4875 ,  A61K31/20 ,  C12R1/00 ,  A23V2200/3262 ,  A23V2200/332 ,  A23V2200/328 ,  A23V2200/02

Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.

Abstract translation: 公开了与真核微生物相关的组合物和方法，其可以产生可纯化和使用的不饱和脂肪酸。

公开(公告)号：US20130344546A1

公开(公告)日：2013-12-26

申请号：US13427562

申请日：2012-03-22

Applicant: Adam Burja ,  Helia Radianingtyas ,  Colin James Barrow ,  Anthony James Windust

Inventor： Adam Burja ,  Helia Radianingtyas ,  Colin James Barrow ,  Anthony James Windust

IPC: C12P7/64

CPC classification number: C12P7/6427 ,  A21D8/04 ,  A23K10/18 ,  A23K20/158 ,  A23L29/065 ,  A23L33/115 ,  A23L33/12 ,  A23L33/135 ,  A23P10/30 ,  A23V2002/00 ,  A61K9/4875 ,  A61K31/20 ,  C12R1/00 ,  A23V2200/3262 ,  A23V2200/332 ,  A23V2200/328 ,  A23V2200/02

Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.