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    Automatic sample testing machine
    1.
    发明授权
    Automatic sample testing machine 有权
    自动样品检测机

    公开(公告)号：US6086824A

    公开(公告)日：2000-07-11

    申请号：US327110

    申请日：1999-06-07

    申请人： Mark Joseph Fanning ,  Jean-Pierre Bernard Gayral ,  Roger James Morris ,  Ron Robinson ,  William Ernest Seaton ,  David B. Shine ,  Paul Springer

    发明人： Mark Joseph Fanning ,  Jean-Pierre Bernard Gayral ,  Roger James Morris ,  Ron Robinson ,  William Ernest Seaton ,  David B. Shine ,  Paul Springer

    IPC分类号： B01L3/00 ,  G01N1/38 ,  G01N35/00 ,  G01N35/10

    CPC分类号： B01L3/50 ,  G01N35/00029 ,  G01N1/38 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/00148 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/114998 ,  Y10T436/115831 ,  Y10T436/119163 ,  Y10T436/25625 ,  Y10T436/2575

    摘要： An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles. The test sample positioning system moves the tray to a cutting and sealing station and then to an incubation station and loads the cards one at a time into a carousel within the incubation station. A test card transport station transports the test cards from the incubation station to an optical reading station, where optical measurements (e.g., transmittance and/or fluorescence optical testing) is conducted on the wells of the card. When the card has been read, it is either moved back to the incubation station for additional incubation and reading or transferred to a card disposal system when the reading is complete.

    摘要翻译： 用于测试存储在测试卡中的样品的自动样品测试机。 该机器具有测试样品定位系统，用于在机器中的各个站之间移动包含多个测试样品卡和流体容器的托盘。 该机器具有用于根据需要向容器添加预定量的稀释剂的稀释站。 移液站将流体从一个容器传送到另一个容器。 设置真空站，其具有可在上位置和下​​位置之间相对于托盘移动的真空室。 当室下降到较低位置时，室与托盘配合以与托盘的顶表面进行密封接合。 真空发生器为腔室提供真空。 当从室释放真空时，将流体样品从容器装载到卡中。 测试样品定位系统将托盘移动到切割和密封站，然后移动到孵化站，并将卡一次装载到孵育站内的转盘中。 测试卡传输站将测试卡从孵化站运送到光学读取站，其中在卡的孔上进行光学测量（例如，透射率和/或荧光光学测试）。 读卡完成后，将其移回孵化站进行额外的孵化和阅读，或者将其转移到卡片处理系统。