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    SELECTIVE STIMULATION TO MODULATE THE SYMPATHETIC NERVOUS SYSTEM
    2.
    发明申请
    SELECTIVE STIMULATION TO MODULATE THE SYMPATHETIC NERVOUS SYSTEM 有权
    选择性刺激来调节症状性神经系统

    公开(公告)号：US20160082258A1

    公开(公告)日：2016-03-24

    申请号：US14954740

    申请日：2015-11-30

    申请人： Jeffery M. KRAMER ,  Daniel H. KIM ,  Mir A. IMRAN

    发明人： Jeffery M. KRAMER ,  Daniel H. KIM ,  Mir A. IMRAN

    IPC分类号： A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/36114 ,  A61N1/0551 ,  A61N1/36057 ,  A61N1/36071 ,  A61N1/36135

    摘要： Systems, methods and devices are provided for the targeted treatment of a variety of medical conditions by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies. Typically, the target anatomy includes one or more dorsal root ganglia, dorsal roots, dorsal root entry zones, or portions thereof. Such target stimulation areas are utilized due in part to their effect on the sympathetic nervous system.

    摘要翻译： 提供了系统，方法和装置，用于通过直接神经调节与条件相关联的目标解剖结构，同时最小化或排除其他解剖结构的不期望的神经调节来定向治疗各种医学状况。 通常，目标解剖结构包括一个或多个背根神经节，背根，背根进入区或其部分。 这些目标刺激区域部分地由于它们对交感神经系统的影响而被利用。

    SELECTIVE STIMULATION SYSTEMS AND SIGNAL PARAMETERS FOR MEDICAL CONDITIONS
    6.
    发明申请
    SELECTIVE STIMULATION SYSTEMS AND SIGNAL PARAMETERS FOR MEDICAL CONDITIONS 有权
    选择性刺激系统和信号参数用于医疗条件

    公开(公告)号：US20150258338A1

    公开(公告)日：2015-09-17

    申请号：US14726359

    申请日：2015-05-29

    申请人： Eyad KISHAWI ,  Mir A. IMRAN ,  Brian J. MOSSOP ,  Jeffery M. KRAMER ,  Richard W. O'CONNER

    发明人： Eyad KISHAWI ,  Mir A. IMRAN ,  Brian J. MOSSOP ,  Jeffery M. KRAMER ,  Richard W. O'CONNER

    IPC分类号： A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/36071 ,  A61N1/0551 ,  A61N1/36157 ,  A61N1/37247

    摘要： Devices, systems and methods are provided for targeted treatment of a variety of conditions, particularly conditions that are associated with or influenced by the nervous system, such as pain. Targeted treatment of such conditions is provided with minimal deleterious side effects, such as undesired motor responses or undesired stimulation of unaffected body regions. This is achieved by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies.

    摘要翻译： 提供装置，系统和方法用于各种条件的靶向治疗，特别是与神经系统相关或受其影响的条件，例如疼痛。 提供这种病症的靶向治疗具有最小的有害副作用，例如不期望的运动反应或不受影响的身体区域的刺激。 这是通过直接神经调节与病症相关的目标解剖结构来实现的，同时最小化或排除其他解剖结构的不希望的神经调节。

    Pain management with stimulation subthreshold to paresthesia
    8.
    发明授权
    Pain management with stimulation subthreshold to paresthesia 有权
    疼痛管理与刺激亚阈值感觉异常

    公开(公告)号：US08380318B2

    公开(公告)日：2013-02-19

    申请号：US12730908

    申请日：2010-03-24

    申请人： Eyad Kishawi ,  Jeffery M. Kramer

    发明人： Eyad Kishawi ,  Jeffery M. Kramer

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36071 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36157

    摘要： Devices, systems and methods are provided for treating pain while minimizing or eliminating possible complications and undesired side effects, particularly the sensation of paresthesia. This is achieved by stimulating in proximity to a dorsal root ganglion with stimulation energy in a manner that will affect pain sensations without generating substantial sensations of paresthesia. In some embodiments, such neurostimulation takes advantage of anatomical features and functions particular to the dorsal root ganglion.

    摘要翻译： 提供装置，系统和方法用于治疗疼痛，同时最小化或消除可能的并发症和不期望的副作用，特别是感觉异常的感觉。 这是通过以刺激能量的方式刺激靠近背根神经节，以影响疼痛感觉而不产生实质感觉异常感的方式来实现的。 在一些实施例中，这种神经刺激利用了背根神经节特有的解剖特征和功能。

    DEVICES, SYSTEMS AND METHODS FOR THE TARGETED TREATMENT OF MOVEMENT DISORDERS
    9.
    发明申请
    DEVICES, SYSTEMS AND METHODS FOR THE TARGETED TREATMENT OF MOVEMENT DISORDERS 有权
    用于治疗运动障碍的装置，系统和方法

    公开(公告)号：US20120158094A1

    公开(公告)日：2012-06-21

    申请号：US13365163

    申请日：2012-02-02

    申请人： Jeffery M. Kramer ,  Robert M. Levy

    发明人： Jeffery M. Kramer ,  Robert M. Levy

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36067 ,  A61B5/0488 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/1123 ,  A61B5/4082 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36071 ,  A61N1/36139 ,  A61N1/36171

    摘要： Devices, systems and methods are provided for the targeted treatment of movement disorders. Typically, the systems and devices are used to stimulate one or more dorsal root ganglia while minimizing or excluding undesired stimulation of other tissues, such as surrounding or nearby tissues, ventral root and portions of the anatomy associated with body regions which are not targeted for treatment. The dorsal root ganglia are utilized in particular due to their specialized role in movement. It is in these areas that sensory fibers are isolated from motor fibers. Sensory fibers are involved in a variety of reflexes that are involved in movement control, and these reflexes can be utilized in the treatment of various movement disorders. Thus, by stimulating sensory fibers in these areas, fundamental reflexes can be affected to lessen the symptoms of movement disorders.

    摘要翻译： 提供了针对运动障碍的目标治疗的装置，系统和方法。 通常，系统和装置用于刺激一个或多个背根神经节，同时最小化或排除其他组织（例如周围或附近组织，腹侧根部和与未被靶向治疗的身体区域相关联的解剖结构的部分）的不希望的刺激 。 背根神经节特别是由于其在运动中的特殊作用而被使用。 在这些区域，感觉纤维与运动纤维隔离。 感觉纤维参与运动控制中涉及的各种反射，并且这些反射可用于治疗各种运动障碍。 因此，通过刺激这些区域的感觉纤维，可以影响基础反射以减轻运动障碍的症状。