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公开(公告)号：US20090298139A1
公开(公告)日：2009-12-03
申请号：US12224149
申请日：2007-02-27
Applicant: Jin Zou , David L. Kaplan , Jin Zou , Peter Y. Wong , David L. Kaplan
Inventor： Jin Zou , David L. Kaplan , Jin Zou , Peter Y. Wong , David L. Kaplan
CPC classification number: C12P17/04
Abstract: The present invention discloses a method for producing polymers in a microscale device. The system utilizes a symmetrically branched system of microchannels interconnecting a plurality of loading decks and re-action chambers. The fluid flow is manipulated by the placement of capillary check valves, mixing areas, and microcomb filters. The system provides for cascading enzymatic biosynthesis pathways wherein any variety of enzymes and reactants can be introduced into the system to produce a final product.
Abstract translation: 本发明公开了一种在微型装置中制备聚合物的方法。 该系统利用互连多个装载甲板和再作用室的对称分支的微通道系统。 通过放置毛细管止回阀，混合区域和微孔过滤器来操纵流体流动。 该系统提供级联的酶生物合成途径，其中可以将任何多种酶和反应物引入系统以产生最终产物。
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公开(公告)号：US20210277172A1
公开(公告)日：2021-09-09
申请号：US17328490
申请日：2021-05-24
Applicant: Lenore DAI , Aditi CHATTOPADHYAY , Elizabeth NOFEN , Jin ZOU , Bonsung KOO
Inventor： Lenore DAI , Aditi CHATTOPADHYAY , Elizabeth NOFEN , Jin ZOU , Bonsung KOO
Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
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3.发明授权Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity 有权分析物传感器，制备和使用这些传感器的方法以及检测分析物活性的方法公开(公告)号：US08420327B2
公开(公告)日：2013-04-16
申请号：US12448101
申请日：2007-12-14
Applicant: April L. Ellis , Yiming Ye , Angela Holder , Yun Huang , Michael Kirberger , Jenny Jie Yang , Jin Zou , Wei Yang
Inventor： April L. Ellis , Yiming Ye , Angela Holder , Yun Huang , Michael Kirberger , Jenny Jie Yang , Jin Zou , Wei Yang
IPC: G01N33/53
CPC classification number: G01N21/6486 , G01N33/542 , G01N33/84 , G01N2333/43595
Abstract: Embodiments of the present disclosure provide for analyte sensors, methods for producing and using the analyte sensors, methods of detecting and/or measuring analyte activity, methods for characterizing analyte cellular activity, methods of detecting pH change in a system, method of controlling the concentration of an analyte in a system, fusion proteins, polynucleotides, and vectors corresponding to the analyte sensors, kits, and the like.
Abstract translation: 本公开的实施方案提供了分析物传感器，用于生产和使用分析物传感器的方法，检测和/或测量分析物活性的方法，用于表征分析物细胞活性的方法，检测系统中pH变化的方法，控制浓度的方法 的系统中的分析物，融合蛋白，多核苷酸和对应于分析物传感器，试剂盒等的载体。
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4.发明申请ANALYTE SENSORS, METHODS FOR PREPARING AND USING SUCH SENSORS, AND METHODS OF DETECTING ANALYTE ACTIVITY 有权分析传感器，用于制备和使用这样的传感器的方法以及检测分析物活性的方法公开(公告)号：US20100196918A1
公开(公告)日：2010-08-05
申请号：US12448101
申请日：2007-12-14
Applicant: April L. Ellis , Yiming Ye , Angela Holder , Yun Huang , Michael Kirberger , Jenny Jie Yang , Jin Zou , Wei Yang
Inventor： April L. Ellis , Yiming Ye , Angela Holder , Yun Huang , Michael Kirberger , Jenny Jie Yang , Jin Zou , Wei Yang
CPC classification number: G01N21/6486 , G01N33/542 , G01N33/84 , G01N2333/43595
Abstract: Embodiments of the present disclosure provide for analyte sensors, methods for producing and using the analyte sensors, methods of detecting and/or measuring analyte activity, methods for characterizing analyte cellular activity, methods of detecting pH change in a system, method of controlling the concentration of an analyte in a system, fusion proteins, polynucleotides, and vectors corresponding to the analyte sensors, kits, and the like.
Abstract translation: 本公开的实施方案提供了分析物传感器，用于生产和使用分析物传感器的方法，检测和/或测量分析物活性的方法，用于表征分析物细胞活性的方法，检测系统中pH变化的方法，控制浓度的方法 的系统中的分析物，融合蛋白，多核苷酸和对应于分析物传感器，试剂盒等的载体。
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Patent Agency Ranking
公开(公告)号：US11753498B2
公开(公告)日：2023-09-12
申请号：US17328490
申请日：2021-05-24
Applicant: Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
Inventor： Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
CPC classification number: C08G59/1477 , C08G59/5006 , C08K5/20 , C08L63/00 , G01L1/241
Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
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公开(公告)号：US11034791B2
公开(公告)日：2021-06-15
申请号：US16349221
申请日：2017-12-20
Applicant: Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
Inventor： Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
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公开(公告)号：US20090301876A1
公开(公告)日：2009-12-10
申请号：US12446896
申请日：2007-10-22
Applicant: Mark Wagner , Jin Zou
Inventor： Mark Wagner , Jin Zou
CPC classification number: G01N27/30 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , Y10T29/49158 , Y10T29/49169
Abstract: This disclosure relates to an improved electrochemical sensor that has a simplified electrode assembly. The electrode assembly incorporates electrodes into or onto a single polymeric substrate. The working electrode can be porous, to enable an analyte, such as a toxic gas, to access an electrode-electrolyte interface. Ionic connection between electrodes can be made by an electrolyte on a back side of the electrode assembly, and external electronic circuitry can be connected directly to the electrode assembly. This construction dramatically simplifies the sensor, resulting in reduced costs and potentially improved performance. The construction is compatible with batch fabrication methods.
Abstract translation: 本公开涉及具有简化的电极组件的改进的电化学传感器。 电极组件将电极并入到单个聚合物基底上或上。 工作电极可以是多孔的，以使诸如有毒气体的分析物能够进入电极 - 电解质界面。 电极之间的离子连接可以由电极组件的背侧上的电解质制成，并且外部电子电路可以直接连接到电极组件。 这种结构大大简化了传感器，从而降低了成本，并提高了性能。 该结构与批量制造方法兼容。
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公开(公告)号：US20240018296A1
公开(公告)日：2024-01-18
申请号：US18356526
申请日：2023-07-21
Applicant: Lenore DAI , Aditi CHATTOPADHYAY , Elizabeth NOFEN , Jin ZOU , Bonsung KOO
Inventor： Lenore DAI , Aditi CHATTOPADHYAY , Elizabeth NOFEN , Jin ZOU , Bonsung KOO
CPC classification number: C08G59/1477 , C08G59/5006 , C08K5/20 , C08L63/00 , G01L1/241
Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
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公开(公告)号：US12258439B2
公开(公告)日：2025-03-25
申请号：US18356526
申请日：2023-07-21
Applicant: Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
Inventor： Lenore Dai , Aditi Chattopadhyay , Elizabeth Nofen , Jin Zou , Bonsung Koo
Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
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