公开(公告)号：US09045744B2

公开(公告)日：2015-06-02

申请号：US14000497

申请日：2012-02-20

申请人： Nam-Soo Kim ,  Chong-Tai Kim ,  Yong-Jin Cho ,  Chul-Jin Kim ,  Jin-Soo Maeng ,  Soo-Jin Kwon

发明人： Nam-Soo Kim ,  Chong-Tai Kim ,  Yong-Jin Cho ,  Chul-Jin Kim ,  Jin-Soo Maeng ,  Soo-Jin Kwon

IPC分类号： C12N9/50 ,  C12Q1/37 ,  C12N9/64 ,  A61K38/48 ,  A61K38/51 ,  A23L1/01 ,  A23L1/03 ,  A23L1/22 ,  A23L1/227 ,  A23L3/015 ,  C12N9/48 ,  C12N9/52 ,  C12N9/76

CPC分类号： C12N9/6481 ,  A23L3/0155 ,  A23L5/17 ,  A23L27/00 ,  A23L27/21 ,  A23L29/06 ,  A61K38/48 ,  A61K38/51 ,  C12N9/48 ,  C12N9/485 ,  C12N9/52 ,  C12N9/6427 ,  C12Q1/37 ,  C12Y304/00

摘要： At least at least one embodiment of the present invention relates to a method for using a high pressure-resistant enzyme in a high pressure condition; a method for promoting the activity of the high pressure-resistant enzyme by means of a high pressure treatment; a composition, which contains the high pressure-resistant enzyme, for decomposing proteins under a high pressure condition; a composition, which contains the composition for decomposing proteins, for preparing natural flavoring substances; a container for high pressure treatment, which contains the composition for decomposing proteins; and a method for measuring the activity of the high pressure-resistant enzyme, which comprises a step of decomposing an azocasein solution serving as a substrate by using the high pressure-resistant enzyme treated under a high pressure condition.

摘要翻译： 本发明的至少一个实施方案涉及在高压条件下使用高耐压酶的方法; 通过高压处理促进高耐压酶的活性的方法; 含有高耐压酶的组合物，用于在高压条件下分解蛋白质; 含有用于分解蛋白质的组合物的组合物，用于制备天然调味物质; 用于高压处理的容器，其包含用于分解蛋白质的组合物; 以及测定高耐压酶的活性的方法，其包括通过使用在高压条件下处理的高耐压酶分解作为底物的偶​​氮酪蛋白溶液的步骤。

公开(公告)号：US20140287424A1

公开(公告)日：2014-09-25

申请号：US14343213

申请日：2012-02-22

申请人： Young Jin Cho ,  Chul Jin Kim ,  Nam Soo Kim ,  Chong Tai Kim ,  Jin Soo Maeng ,  Tae Eun Kim ,  Myung Hyun Lee

发明人： Young Jin Cho ,  Chul Jin Kim ,  Nam Soo Kim ,  Chong Tai Kim ,  Jin Soo Maeng ,  Tae Eun Kim ,  Myung Hyun Lee

IPC分类号： C12Q1/68 ,  G01N33/569

CPC分类号： C12Q1/689 ,  C12N15/111 ,  C12N2310/16 ,  C12N2320/10 ,  C12Q1/04 ,  G01N33/5017 ,  G01N33/54366 ,  G01N33/553 ,  G01N33/56911 ,  G01N33/56916 ,  G01N33/56938

摘要： The present invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof. More particularly, the invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof, the slide chip comprising: a substrate coated with a metal; a linker having a substituent which may be bonded to the metal and is located at the 5′ end of deoxythymidine (dT); and a food-borne bacterium-derived RNA aptamer that is bound to the linker by the 3′-end poly A tail. The slide chip makes it possible to detect food-borne bacteria in a rapid and accurate manner.

摘要翻译： 本发明涉及一种用于检测食源性细菌的传感器的滑动片及其制造方法。 更具体地说，本发明涉及一种用于检测食源性细菌的传感器的滑动芯片及其制造方法，该滑动芯片包括：涂覆有金属的基板; 具有可以与金属键合并位于脱氧胸苷（dT）的5'端的取代基的连接体; 以及通过3'末端聚A尾部与接头结合的食源性细菌衍生的RNA适配体。 幻灯片使得可以以快速和准确的方式检测食源性细菌。

公开(公告)号：US20130330758A1

公开(公告)日：2013-12-12

申请号：US14000497

申请日：2012-02-20

申请人： Nam-Soo Kim ,  Chong-Tai Kim ,  Yong-Jin Cho ,  Chul-Jin Kim ,  Jin-Soo Maeng ,  Soo-Jin Kwon

发明人： Nam-Soo Kim ,  Chong-Tai Kim ,  Yong-Jin Cho ,  Chul-Jin Kim ,  Jin-Soo Maeng ,  Soo-Jin Kwon

IPC分类号： C12N9/64 ,  C12N9/48 ,  C12N9/52 ,  C12N9/76

CPC分类号： C12N9/6481 ,  A23L3/0155 ,  A23L5/17 ,  A23L27/00 ,  A23L27/21 ,  A23L29/06 ,  A61K38/48 ,  A61K38/51 ,  C12N9/48 ,  C12N9/485 ,  C12N9/52 ,  C12N9/6427 ,  C12Q1/37 ,  C12Y304/00

摘要： At least at least one embodiment of the present invention relates to a method for using a high pressure-resistant enzyme in a high pressure condition; a method for promoting the activity of the high pressure-resistant enzyme by means of a high pressure treatment; a composition, which contains the high pressure-resistant enzyme, for decomposing proteins under a high pressure condition; a composition, which contains the composition for decomposing proteins, for preparing natural flavoring substances; a container for high pressure treatment, which contains the composition for decomposing proteins; and a method for measuring the activity of the high pressure-resistant enzyme, which comprises a step of decomposing an azocasein solution serving as a substrate by using the high pressure-resistant enzyme treated under a high pressure condition.

摘要翻译： 本发明的至少一个实施方案涉及在高压条件下使用高耐压酶的方法; 通过高压处理促进高耐压酶的活性的方法; 含有高耐压酶的组合物，用于在高压条件下分解蛋白质; 含有用于分解蛋白质的组合物的组合物，用于制备天然调味物质; 用于高压处理的容器，其包含用于分解蛋白质的组合物; 以及测定高耐压酶的活性的方法，其包括通过使用在高压条件下处理的高耐压酶分解作为底物的偶​​氮酪蛋白溶液的步骤。

公开(公告)号：US10036073B2

公开(公告)日：2018-07-31

申请号：US14343213

申请日：2012-02-22

申请人： Young Jin Cho ,  Chul Jin Kim ,  Nam Soo Kim ,  Chong Tai Kim ,  Jin Soo Maeng ,  Tae Eun Kim ,  Myung Hyun Lee

发明人： Young Jin Cho ,  Chul Jin Kim ,  Nam Soo Kim ,  Chong Tai Kim ,  Jin Soo Maeng ,  Tae Eun Kim ,  Myung Hyun Lee

IPC分类号： C12Q1/68 ,  C12Q1/689 ,  C12Q1/04 ,  G01N33/543 ,  G01N33/553 ,  G01N33/569 ,  G01N33/50 ,  C12N15/11

CPC分类号： C12Q1/689 ,  C12N15/111 ,  C12N2310/16 ,  C12N2320/10 ,  C12Q1/04 ,  G01N33/5017 ,  G01N33/54366 ,  G01N33/553 ,  G01N33/56911 ,  G01N33/56916 ,  G01N33/56938

摘要： The present invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof. More particularly, the invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof, the slide chip comprising: a substrate coated with a metal; a linker having a substituent which may be bonded to the metal and is located at the 5′ end of deoxythymidine (dT); and a food-borne bacterium-derived RNA aptamer that is bound to the linker by the 3′-end poly A tail. The slide chip makes it possible to detect food-borne bacteria in a rapid and accurate manner.