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公开(公告)号：US20100047219A1
公开(公告)日：2010-02-25
申请号：US12442769
申请日：2007-09-26
Applicant: Joseph D. Ceccoli , Brian Costello , Sreekumar Pillai
Inventor： Joseph D. Ceccoli , Brian Costello , Sreekumar Pillai
CPC classification number: A61Q19/08 , A61K8/9706 , A61K2800/522 , A61K2800/85 , A61Q17/04
Abstract: An extract of the marine algae, Sarcodiotheca, and more particularly Sarcodiotheca gaudichaudii, is described for use in cosmetic compositions. A biofermentation of Sarcodiotheca, such as for example S. gaudichaudii, is also described. This marine bioferment is useful as a skin care active ingredient for anti-aging cosmetic applications, and particularly useful when used in combination with an extracts of red algae, such as Chondrus crispus.
Abstract translation: 描述了用于化妆品组合物中的海藻，Sarcodiotheca，更特别是Sarcodiotheca gaudichaudii的提取物。 还描述了Sarcodiotheca的生物发酵，例如S. gaudichaudii。 这种海洋生物发酵可用作用于抗衰老化妆品应用的护肤活性成分，并且当与红藻类的提取物例如Chondrus crispus组合使用时特别有用。
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公开(公告)号：US09717932B2
公开(公告)日：2017-08-01
申请号：US13473035
申请日：2012-05-16
Applicant: Joseph D. Ceccoli , Brian Costello , Sreekumar Pillai
Inventor： Joseph D. Ceccoli , Brian Costello , Sreekumar Pillai
CPC classification number: A61Q19/08 , A61K8/9706 , A61K2800/522 , A61K2800/85 , A61Q17/04
Abstract: An extract of the marine algae, Sarcodiotheca, and more particularly Sarcodiotheca gaudichaudii, is described for use in cosmetic compositions. A biofermentation of Sarcodiotheca, such as for example S. gaudichaudii, is also described. This marine bioferment is useful as a skin care active ingredient for anti-aging cosmetic applications, and particularly useful when used in combination with an extracts of red algae, such as Chondrus crispus.
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公开(公告)号：US20170233326A1
公开(公告)日：2017-08-17
申请号：US15115338
申请日：2015-02-05
Applicant: Joseph D. CECCOLI , Michael L. INGRASSIA , Christopher M. JUDD , Brian R. COSTELLO , Biocogent, LLC
Inventor： Joseph D. Ceccoli , Michael L. Ingrassia , Christopher M. Judd , Brian R. Costello , Maciej Bernard Szczepanik
IPC: C07C67/08 , A61K31/618 , A61Q19/00 , C07C69/84 , A61K8/37
CPC classification number: C07C67/08 , A61K8/37 , A61K31/618 , A61K2800/10 , A61Q19/00 , C07C69/84
Abstract: The present technology relates to synthesis of resveratrol compositions, in particular to methods of synthesizing resveratrol salicylates such as those formed through the activation of resveratrol and salicylic acid, and cosmetic and pharmaceutical compositions comprising the same.
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公开(公告)号：US20120258131A1
公开(公告)日：2012-10-11
申请号：US13473035
申请日：2012-05-16
Applicant: Brian COSTELLO , Joseph D. CECCOLI , Sreekumar PILLAI
Inventor： Brian COSTELLO , Joseph D. CECCOLI , Sreekumar PILLAI
CPC classification number: A61Q19/08 , A61K8/9706 , A61K2800/522 , A61K2800/85 , A61Q17/04
Abstract: An extract of the marine algae, Sarcodiotheca, and more particularly Sarcodiotheca gaudichaudii, is described for use in cosmetic compositions. A biofermentation of Sarcodiotheca, such as for example S. gaudichaudii, is also described. This marine bioferment is useful as a skin care active ingredient for anti-aging cosmetic applications, and particularly useful when used in combination with an extracts of red algae, such as Chondrus crispus.
Abstract translation: 描述了用于化妆品组合物中的海藻，Sarcodiotheca，更特别是Sarcodiotheca gaudichaudii的提取物。 还描述了Sarcodiotheca的生物发酵，例如S. gaudichaudii。 这种海洋生物发酵可用作用于抗衰老化妆品应用的护肤活性成分，并且当与红藻类的提取物例如Chondrus crispus组合使用时特别有用。
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公开(公告)号：US20170158599A1
公开(公告)日：2017-06-08
申请号：US15327294
申请日：2015-07-17
Applicant: Joseph D. CECCOLI , Michael L. INGRASSIA , Christopher M. JUDD , Brian R. COSTELLO , Biocogent, LLC
Inventor： Joseph D. Ceccoli , Brian R. Costello , Michael L. Ingrassia , Christopher M. Judd
CPC classification number: C07C67/08 , A61K8/37 , A61K8/85 , A61K31/765 , A61K2800/74 , A61Q19/00 , A61Q19/005 , C07C67/18 , C08G63/065 , C08G63/81 , C07C69/84 , C07C69/86
Abstract: The present technology relates to synthesis of compositions comprising salicylates, polysalicylates and other derivatives of salicylic acid, and personal care and pharmaceutical compositions comprising the same.
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Patent Agency Ranking
6.发明授权Topical compositions for inhibiting matrix metalloproteases and providing antioxidative activities 有权用于抑制基质金属蛋白酶并提供抗氧化活性的局部组合物公开(公告)号：US08435541B2
公开(公告)日：2013-05-07
申请号：US12874884
申请日：2010-09-02
Applicant: Joseph D. Ceccoli , Brian Costello , James A. Hayward , Konstantinos M. Lahanas
Inventor： Joseph D. Ceccoli , Brian Costello , James A. Hayward , Konstantinos M. Lahanas
IPC: A61K8/97
CPC classification number: A61Q19/08 , A61K8/64 , A61K8/97 , A61K8/9706 , A61K2800/782 , A61Q19/005
Abstract: A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of metalloprotease (TIMP) inducing activity, and immediate and delayed antioxidative activity. Preferably, the topical composition comprises at least one MMP inhibitor, a TIMP inducing agent, Tremella fuciformis (snow fungus) extract, Camellia sinensis (green tea) leaf extract, and Eugenia caryophyllus (clove) extract. The compositions are useful in anti-wrinkle and anti-aging products, providing elasticity, firmness, tone and texture to the skin, ameliorating fine lines and preventing skin damage.
Abstract translation: 本发明的用于提供基质金属蛋白酶（MMP）抑制活性的皮肤护理方案，金属蛋白酶（TIMP）诱导活性的组织抑制剂）和立即和延迟的抗氧化活性的局部组合物。 优选地，所述局部组合物包含至少一种MMP抑制剂，TIMP诱导剂，银耳银耳（雪母）提取物，山茶花（绿茶）叶提取物和丁香菊（Eugenia caryophyllus）（丁香）提取物。 该组合物可用于抗皱和抗衰老产品，为皮肤提供弹性，坚固度，色调和质地，改善细纹并防止皮肤损伤。
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7.发明申请TOPICAL COMPOSITIONS FOR INHIBITING MATRIX METALLOPROTEASES AND PROVIDING ANTIOXIDATIVE ACTIVITIES 有权用于抑制基质金属元素和提供抗氧化活性的主题组合物公开(公告)号：US20120058140A1
公开(公告)日：2012-03-08
申请号：US12874884
申请日：2010-09-02
Applicant: Joseph D. Ceccoli , Brian Costello , James A. Hayward , Konstantinos M. Lahanas
Inventor： Joseph D. Ceccoli , Brian Costello , James A. Hayward , Konstantinos M. Lahanas
CPC classification number: A61Q19/08 , A61K8/64 , A61K8/97 , A61K8/9706 , A61K2800/782 , A61Q19/005
Abstract: A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of metalloprotease (TIMP) inducing activity, and immediate and delayed antioxidative activity. Preferably, the topical composition comprises at least one MMP inhibitor, a TIMP inducing agent, Tremella fuciformis (snow fungus) extract, Camellia sinensis (green tea) leaf extract, and Eugenia caryophyllus (clove) extract. The compositions are useful in anti-wrinkle and anti-aging products, providing elasticity, firmness, tone and texture to the skin, ameliorating fine lines and preventing skin damage.
Abstract translation: 本发明的用于提供基质金属蛋白酶（MMP）抑制活性的皮肤护理方案，金属蛋白酶（TIMP）诱导活性的组织抑制剂）和立即和延迟的抗氧化活性的局部组合物。 优选地，所述局部组合物包含至少一种MMP抑制剂，TIMP诱导剂，银耳银耳（雪母）提取物，山茶花（绿茶）叶提取物和丁香菊（Eugenia caryophyllus）（丁香）提取物。 该组合物可用于抗皱和抗衰老产品，为皮肤提供弹性，坚固度，色调和质地，改善细纹并防止皮肤损伤。
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公开(公告)号：US5942501A
公开(公告)日：1999-08-24
申请号：US699150
申请日：1996-08-16
Applicant: James A. Hayward , James Maioriello , Joseph D. Ceccoli
Inventor： James A. Hayward , James Maioriello , Joseph D. Ceccoli
CPC classification number: B82Y5/00 , A61K31/60 , A61K47/48969
Abstract: A salicylic acid (SA) and derivitized beta cyclodextrin complex provides that the SA display increased solubility in water. The complex includes about 0.1 to about 10.0 percent salicylic acid, about 0.1 to about 75.0 percent derivatized beta cyclodextrin and about 0.1 to about 50.0 percent water.
Abstract translation: 水杨酸（SA）和衍生的β-环糊精复合物提供SA显示增加在水中的溶解度。 复合物包括约0.1至约10.0％的水杨酸，约0.1至约75.0％的衍生的β-环糊精和约0.1至约50.0％的水。
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9.发明授权Cosmetic delivery system for salicylic acid and process for preparation of same 失效水杨酸的化妆品输送系统及其制备方法
公开(公告)号：US5585109A
公开(公告)日：1996-12-17
申请号：US518956
申请日：1995-08-24
Applicant: James A. Hayward , Mindy S. Goldstein , Miriam Brown , Joseph D. Ceccoli
Inventor： James A. Hayward , Mindy S. Goldstein , Miriam Brown , Joseph D. Ceccoli
IPC: A61K8/30 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/33 , A61K8/368 , A61K8/44 , A61K8/55 , A61K8/58 , A61K9/127 , A61K31/60 , A61P17/00 , A61Q19/00 , B01J13/06
CPC classification number: A61K8/368 , A61K8/14 , A61Q19/00 , A61K2800/75
Abstract: A cosmetic composition and salicylic acid delivery system includes membrane lipid bylayers formed as liposomes and un-neutralized salicylic acid localized within the lipidic bylayers of the liposomes. Other cosmetic ingredients may be located either within the membrane compartment or in either the external or internal aqueous compartments relative the liposomal bylayers. The composition also includes an organic, water-soluble membrane-impermeant base and water.
Abstract translation: 化妆品组合物和水杨酸递送系统包括作为脂质体形成的膜脂质层和位于脂质体的脂质层内的未中和的水杨酸。 其他化妆品成分可以位于膜隔室内，也可以位于相对于脂质体层的外部或内部水性隔室中。 该组合物还包括有机的水溶性膜 - 不渗透基质和水。
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公开(公告)号：US4777564A
公开(公告)日：1988-10-11
申请号：US122606
申请日：1987-11-17
Applicant: Dennis J. Derfiny , Joseph D. Ceccoli , Emery E. Baxter
Inventor： Dennis J. Derfiny , Joseph D. Ceccoli , Emery E. Baxter
CPC classification number: H05K3/3426 , H01L23/49555 , H01R12/57 , H05K1/0271 , H01L2924/0002 , H01L2924/09701 , H05K2201/09063 , H05K2201/09072 , H05K2201/10636 , H05K2201/10651 , H05K2201/10772 , H05K2201/2036 , H05K2203/0191 , H05K3/305 , Y02P70/611 , Y02P70/613
Abstract: An improved leadform for use with surface mount components is described. The improved leadform provides a connection to a printed circuit substrate which is highly resistant to stress related failures. The leadform is configured so that the connection utilizes a relatively greater area of the leadform for contact with a solder connection resulting in a more compliant connection. In addition, the present invention provides a preparation for the printed circuit media which allows the substrate media to absorb stresses which occur due to thermal cycling.
Abstract translation: 描述了一种用于表面安装部件的改进的引线形式。 改进的引线形式提供与印刷电路基板的连接，其高度抵抗与应力相关的故障。 引线形状被配置为使得连接利用引线形式的相对较大的区域与焊接连接接触，导致更顺从的连接。 此外，本发明提供了印刷电路介质的准备，其允许基板介质吸收由于热循环而发生的应力。
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