Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof
    1.
    发明授权
    Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof 失效
    筛选人KIAA0001受体及其配体之间相互作用的激动剂和拮抗剂的方法

    公开(公告)号:US06238873B1

    公开(公告)日:2001-05-29

    申请号:US09303524

    申请日:1999-04-30

    CPC classification number: C07K14/705 C07K2319/00 G01N2333/726 G01N2500/20

    Abstract: Disclosed are methods for discovering agonists and antagonists of the interaction between UDP-glucose, UDP-galactose, UDP-glucuronic acid, UDP-N-acetyl glucosamine, as well as related UDP sugars, and their cellular receptor, human KIAA0001, which may have utility in the treatment of several human diseases and disorders, including, but not limited to: infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; diabetes, obesity; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; restenosis; atherosclerosis; diseases characterized by excessive smooth muscle cell proliferation; aneurysms; wound healing; diseases characterized by loss of smooth muscle cells or reduced smooth muscle cell proliferation; stroke; ischemia; ulcers; asthma; allergies; benign prostatic hypertrophy; migraine; vomiting; psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, depression, delirium, dementia, and severe mental retardation; degenerative diseases, such as neurodegenerative diseases and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others.

    Abstract translation: 公开了用于发现UDP-葡萄糖,UDP-半乳糖,UDP-葡糖醛酸,UDP-N-乙酰葡糖胺以及相关的UDP糖和它们的细胞受体之间的相互作用的激动剂和拮抗剂的方法,人类KIAA0001可能具有 包括但不限于:细菌,真菌,原生动物和病毒感染等感染,尤其是HIV-1或HIV-2引起的感染; 疼痛; 癌症; 糖尿病,肥胖; 厌食症 贪食 哮喘; 帕金森病 急性心力衰竭 低血压 高血压; 尿潴留 骨质疏松症 心绞痛; 心肌梗死; 再狭窄; 动脉粥样硬化 以过度平滑肌细胞增殖为特征的疾病; 动脉瘤 伤口愈合; 特征在于平滑肌细胞丧失或平滑肌细胞增殖减少的疾病; 行程; 缺血; 溃疡 哮喘; 过敏 良性前列腺肥大; 偏头痛 呕吐 精神病和神经障碍,包括焦虑,精神分裂症,躁狂抑郁症,抑郁症,del妄,痴呆和严重智力迟钝; 退行性疾病,如神经退行性疾病和运动障碍,如亨廷顿病或吉尔斯·德拉·图雷特综合征等。

    Generator hydrogen purge gas economizer with membrane filter
    2.
    发明授权
    Generator hydrogen purge gas economizer with membrane filter 失效
    发电机氢气清洗气节能器与膜过滤器

    公开(公告)号:US6126726A

    公开(公告)日:2000-10-03

    申请号:US110523

    申请日:1998-07-06

    Abstract: A turbine generator hydrogen filtration system having an improved membrane filter for the removal of gases and particulates is provided. The system comprises a membrane filter operably connected with defoaming tanks. The hydrogen stream is routed through an improved membrane filter where air and other contaminants such as oil are removed. The hydrogen is recirculated into the hydrogen cooled generator. The membrane filter employed in the system is one of several palladium based membrane filters which effectively remove air and other contaminants and provide high hydrogen through-put.

    Abstract translation: 提供了一种具有用于去除气体和微粒的改进的膜过滤器的涡轮发电机氢过滤系统。 该系统包括与消泡罐可操作地连接的膜过滤器。 氢气流通过改进的膜过滤器,其中除去空气和其它污染物如油。 氢再循环到氢冷发电机中。 系统中使用的膜过滤器是几种基于钯的膜过滤器之一,其有效地去除空气和其它污染物并提供高氢气通量。

    Methods and Systems for Improving RFID Security
    3.
    发明申请
    Methods and Systems for Improving RFID Security 审中-公开
    改进RFID安全的方法和系统

    公开(公告)号:US20080094220A1

    公开(公告)日:2008-04-24

    申请号:US11875807

    申请日:2007-10-19

    Abstract: The present invention provides various techniques to improve the security of data transmissions in RFID systems. Systems and methods for constructing more secure RFID tags, readers, and servers are disclosed enabling individuals to minimize privacy exposure while taking care to avoid needlessly overcomplicating the user's RFID transactions.

    Abstract translation: 本发明提供了用于提高RFID系统中的数据传输的安全性的各种技术。 公开了用于构建更安全的RFID标签,读取器和服务器的系统和方法,使得个人能够在注意避免不必要地过度使用用户的RFID交易的情况下最小化隐私暴露。

    Remodeler light fixture support structure and method
    4.
    发明授权
    Remodeler light fixture support structure and method 失效
    改装灯具支架结构及方法

    公开(公告)号:US5957572A

    公开(公告)日:1999-09-28

    申请号:US884006

    申请日:1997-06-27

    Abstract: A method, system and apparatus for supporting a light fixture in an aperture formed in a planar member is disclosed. An aperture is first cut in the planar member at the point where the lighting fixture is to be installed and a light fixture support structure having at least two mounting straps positioned about the perimeter of the light fixture support structure for retaining the light fixture support structure in position in the aperture formed in the planar member is positioned in the aperture by an installer. The light fixture support structure mounting straps are then positioned contiguous with the inner surface of the planar member and are manipulated such that the light fixture support structure is maintained in position in the aperture. The light fixture support structure includes a perimeter member having a wall portion and a lip portion and having at least two slots formed at the junction of the wall and the lip and at least two mounting straps positioned in the at least two slots for retaining the light fixture support structure in position in the aperture formed in the planar member. The mounting strap including a hook member at one end and a v shaped two leg member at the other end with each of the legs having a flange member for engaging the surface of the planar member. Methods of installing remodeler light fixtures in a planar member are also disclosed.

    Abstract translation: 公开了一种用于在形成在平面构件中的孔中支撑灯具的方法,系统和装置。 首先在平面构件中在要安装照明器具的位置处切割孔,以及灯具支撑结构,其具有围绕灯具支撑结构的周边定位的至少两个安装带,用于将灯具支撑结构保持在 在平面构件中形成的孔中的位置由安装者定位在孔中。 然后将灯具支撑结构安装带定位成与平面构件的内表面邻接并被操纵,使得灯具支撑结构保持在孔中的适当位置。 灯具支撑结构包括具有壁部分和唇缘部分的周边构件,并且具有形成在壁和唇缘的接合部处的至少两个狭槽和至少两个安装带,所述至少两个安装带定位在至少两个狭槽中,用于保持光线 固定支撑结构在平面构件中形成的孔中的位置。 所述安装带在一端包括钩构件,在另一端具有v形的双腿构件,每个腿具有用于接合平面构件的表面的凸缘构件。 还公开了在平面构件中安装改造器灯具的方法。

    Recessed fixture frame and method
    6.
    发明授权
    Recessed fixture frame and method 失效
    嵌入式夹具框架和方法

    公开(公告)号:US5957573A

    公开(公告)日:1999-09-28

    申请号:US924349

    申请日:1997-09-05

    CPC classification number: F21V21/30 F21V21/04 F21V27/00

    Abstract: An improved recessed fixture frame and method for installing the recessed fixture frame in new, existing or rough-in construction is disclosed. The improved recessed fixture frame includes a frame band for supporting and surrounding a fixture housing and at least one mounting assembly connected to the frame band in such a manner that the frame band is capable of being adjusted between the ends of the mounting bars. The mounting assembly includes at least one hinged mounting stub operatively hingeably connected to at least one end of the mounting assembly. Each hinged mounting stub includes a fastening means for affixing the recessed fixture frame to a structural member in a first position. In the first position, the recessed fixture frame extends downwardly from the structural member. After the fixture frame has been wired-in, the fixture frame is rotated about ninety degrees (90.degree.) about the hinged mounting stubs to a second position where the non-hinged mounting stub at the other end of the mounting assemblies are operatively connected to a second structural member.

    Abstract translation: 公开了一种改进的嵌入式固定框架和用于将新的,现有的或粗糙的结构中的嵌入式固定框架安装的方法。 改进的凹入的固定框架包括用于支撑和围绕固定件壳体的框架带和连接到框架带的至少一个安装组件,使得框架带能够在安装杆的端部之间进行调节。 安装组件包括至少一个可铰接地连接到安装组件的至少一个端部的铰接安装短截线。 每个铰接安装短截线包括紧固装置,用于将凹入的固定框架固定在第一位置的结构构件上。 在第一位置,凹入的固定框架从结构构件向下延伸。 在固定框架已经接线之后,固定框架围绕铰接的安装支柱旋转大约九十度(90度)到第二位置,其中安装组件的另一端的非铰接安装支柱可操作地连接到 第二结构构件。

    Systems and methods for collection and detection of particulates in the air
    7.
    发明授权
    Systems and methods for collection and detection of particulates in the air 失效
    收集和检测空气中微粒的系统和方法

    公开(公告)号:US08205512B1

    公开(公告)日:2012-06-26

    申请号:US12228899

    申请日:2008-08-15

    CPC classification number: G01N1/2273 G01N1/2211 G01N1/24

    Abstract: Embodiments include systems and methods for collection and identification of particulates in the air. In one embodiment, two different path ways are provided from a single adjustable inlet: one for collection and one for detection. A removable insert positionable within a collection tube enables a user to switch between the collection mode and the detection mode. This embodiment captures both the physical mechanisms of switching the air flow paths as well as sequencing of controls and valves and regulation or changing the air flow rate in the different modes of operation. This and other embodiments are disclosed herein.

    Abstract translation: 实施例包括用于收集和识别空气中的颗粒物的系统和方法。 在一个实施例中,从单个可调节入口提供两个不同的路径:一个用于收集,另一个用于检测。 定位在收集管内的可移除插入件使得用户能够在收集模式和检测模式之间切换。 该实施例捕获了切换空气流动路径的物理机制以及控制和阀的排序以及在不同操作模式中调节或改变空气流速。 这里和其他实施例在此公开。

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