公开(公告)号：US20050238538A1

公开(公告)日：2005-10-27

申请号：US11106352

申请日：2005-04-14

申请人： James Braig ,  Gary Hewett ,  Michael Munrow ,  Julian Cortella ,  Kamrava Azizi ,  Daniel Goldberger

发明人： James Braig ,  Gary Hewett ,  Michael Munrow ,  Julian Cortella ,  Kamrava Azizi ,  Daniel Goldberger

IPC分类号： A61B5/00 ,  G06F19/00 ,  G01N21/00

CPC分类号： A61B5/1495 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1455 ,  A61B2560/0271 ,  A61B2562/0295 ,  G06F19/3418 ,  G16H40/40 ,  G16H40/63 ,  Y10S707/99945

摘要： An analyte concentration monitoring system having network-based communication features which provide a link between an analyte detection system and a centralized computer. The analyte detection system has a processor that calculates analyte concentration in accordance with software executable by the processor. Under certain conditions, the software needs to be updated. Accordingly, when the analyte detection system is connected to the centralized computer, the centralized computer determines whether a software update is needed. If a software update is needed, then the centralized computer conveniently provides the software update to the analyte detection system without intervention from a user.

公开(公告)号：US06631282B2

公开(公告)日：2003-10-07

申请号：US09970021

申请日：2001-10-02

申请人： Peter Rule ,  James R. Braig ,  Daniel S. Goldberger ,  Julian Cortella ,  Mark D. Agostino

发明人： Peter Rule ,  James R. Braig ,  Daniel S. Goldberger ,  Julian Cortella ,  Mark D. Agostino

IPC分类号： A61B500

CPC分类号： A61B5/6841 ,  A61B5/061 ,  A61B5/14532 ,  A61B5/1455

摘要： A device and method are provided for use with a non-invasive optical measurement system, such as a thermal gradient spectrometer for improved determination of analyte concentrations within living tissue. In a preferred embodiment, a site selector is secured to a patient's forearm thereby isolating a measurement site on the patient's skin for determination of blood glucose levels. The site selector attaches to a thermal mass window of the spectrometer and thus forms an interface between the patient's skin and the thermal mass window. When the spectrometer must be temporarily removed from the patient's skin, such as to allow the patient mobility, the site selector is left secured to the forearm so as to maintain a consistent measurement site on the skin. When the spectrometer is later reattached to the patient, the site selector will again form an interface between the gradient spectrometer and the same location of skin as before.

摘要翻译： 提供了一种用于非侵入式光学测量系统的装置和方法，所述非侵入性光学测量系统例如用于改善生物体内分析物浓度测定的热梯度光谱仪。 在优选实施例中，站点选择器被固定到患者的前臂，从而隔离患者皮肤上的测量部位以确定血糖水平。 站点选择器连接到光谱仪的热质量窗口，从而形成患者皮肤和热质量窗口之间的界面。 当光谱仪必须临时从病人的皮肤上移除时，例如允许患者移动，将场地选择器固定在前臂上，以保持皮肤上一致的测量部位。 当光谱仪后来重新连接到患者时，站点选择器将再次形成梯度光谱仪和与之前相同的皮肤位置之间的界面。

公开(公告)号：US06198949B1

公开(公告)日：2001-03-06

申请号：US09265195

申请日：1999-03-10

申请人： James R. Braig ,  Bernhard B. Sterling ,  Daniel S. Goldberger ,  Joan C. Godfrey ,  Julian Cortella ,  David J. Correia ,  Arthur M. Shulenberger ,  Charles E. Kramer

发明人： James R. Braig ,  Bernhard B. Sterling ,  Daniel S. Goldberger ,  Joan C. Godfrey ,  Julian Cortella ,  David J. Correia ,  Arthur M. Shulenberger ,  Charles E. Kramer

IPC分类号： A61B500

CPC分类号： A61B5/01 ,  A61B5/14532 ,  G01J3/02 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/42 ,  G01J5/061

摘要： A solid-state spectrometer for the non-invasive generation and capture of thermal gradient spectra from human or animal tissue. The spectrometer includes an infrared transmissive thermal mass window for inducing a transient temperature gradient in the tissue by means of conductive heat transfer with the tissue, and a cooling element in operative combination with the thermal mass window for cooling the thermal mass window. Also provided is an infrared sensor for detecting infrared emissions emanating from the tissue as the transient temperature gradient progresses into the tissue, and for providing output signals proportional to the detected infrared emissions. A data capture element is provided for sampling the output signals received from the infrared sensor as the transient temperature gradient progresses into the tissue.

摘要翻译： 一种用于非侵入性生成和捕获来自人或动物组织的热梯度光谱的固态光谱仪。 光谱仪包括用于通过与组织的导电热传递在组织中诱导瞬时温度梯度的红外透射热质窗口，以及与用于冷却热质量窗口的热质量窗口可操作组合的冷却元件。 还提供了一种红外传感器，用于当瞬态温度梯度进入组织时检测从组织发出的红外辐射，并提供与检测到的红外发射成比例的输出信号。 提供数据采集元件，用于对瞬态温度梯度进入组织中的红外传感器接收的输出信号进行采样。

公开(公告)号：US06636753B1

公开(公告)日：2003-10-21

申请号：US09760423

申请日：2001-01-11

申请人： James R. Braig ,  Bernhard B. Sterling ,  Daniel S. Goldberger ,  Joan C. Godfrey ,  Julian Cortella ,  David J. Correia ,  Arthur M. Shulenberger ,  Charles E. Kramer

发明人： James R. Braig ,  Bernhard B. Sterling ,  Daniel S. Goldberger ,  Joan C. Godfrey ,  Julian Cortella ,  David J. Correia ,  Arthur M. Shulenberger ,  Charles E. Kramer

IPC分类号： A61B500

CPC分类号： A61B5/01 ,  A61B5/14532 ,  G01J3/02 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/42 ,  G01J5/061

摘要： A solid-state spectrometer for the non-invasive generation and capture of thermal gradient spectra from human or animal tissue. The spectrometer includes an infrared transmissive thermal mass window for inducing a transient temperature gradient in the tissue by means of conductive heat transfer with the tissue, and cooling means in operative combination with the thermal mass window for cooling the thermal mass window. Also provided is an infrared sensor means for detecting infrared emissions emanating from the tissue as the transient temperature gradient progresses into the tissue, and for providing output signals proportional to the detected infrared emissions. Data capture means is provided for sampling the output signals received from the infrared sensor means as the transient temperature gradient progresses into the tissue.

摘要翻译： 一种用于非侵入性生成和捕获来自人或动物组织的热梯度光谱的固态光谱仪。 光谱仪包括红外透射热质窗口，用于通过与组织的导电热传递来诱导组织中的瞬态温度梯度，以及与用于冷却热质量窗口的热质量窗口可操作组合的冷却装置。 还提供了一种红外传感器装置，用于当瞬态温度梯度进入组织时检测从组织发出的红外辐射，并提供与检测到的红外发射成比例的输出信号。 提供数据捕获装置，用于当瞬态温度梯度进入组织时对从红外传感器装置接收的输出信号进行采样。