公开(公告)号：US09005400B2

公开(公告)日：2015-04-14

申请号：US13221497

申请日：2011-08-30

Applicant: Mark Wechsler ,  James Braig R

Inventor： Mark Wechsler ,  James Braig R

IPC: C10B47/00 ,  C10L9/08 ,  C10B53/02 ,  C10L1/02 ,  C10B47/44 ,  C10L9/02 ,  C10G45/72 ,  C10L5/44 ,  G01J3/42 ,  G01J3/453

CPC classification number: C10L9/083 ,  C10B47/44 ,  C10B53/02 ,  C10G45/72 ,  C10G2300/1011 ,  C10G2300/30 ,  C10G2300/708 ,  C10L1/02 ,  C10L5/44 ,  C10L9/02 ,  F26B2200/24 ,  G01J3/42 ,  G01J3/453 ,  Y02E50/10 ,  Y02E50/14 ,  Y02E50/15 ,  Y02E50/30

Abstract: Embodiments presented herein describe an apparatus and method to control the conversion of carbonaceous materials, particularly biomass and those biomass resources, into a high performance solid fuel. This method, and the apparatus described as the means to accomplish this method, provides a process having a control system that enables the system to produce a fuel of uniform quality, even with a change in biomass supply.

Abstract translation: 本文提出的实施方案描述了控制碳质材料，特别是生物量和那些生物质资源转化成高性能固体燃料的装置和方法。 该方法以及描述为实现该方法的手段的装置提供了一种具有控制系统的过程，即使在生物质供应的变化的情况下，也能使系统产生质量均匀的燃料。

公开(公告)号：US20080072663A1

公开(公告)日：2008-03-27

申请号：US11839487

申请日：2007-08-15

Applicant: Richard Keenan ,  Jeffrey Chiou ,  Roger Tong ,  Michael Recknor ,  Ken Li ,  James Braig ,  David Callicoat ,  Jennifer Gable

Inventor： Richard Keenan ,  Jeffrey Chiou ,  Roger Tong ,  Michael Recknor ,  Ken Li ,  James Braig ,  David Callicoat ,  Jennifer Gable

IPC: G01N33/00 ,  B01J19/00 ,  B04B5/10

CPC classification number: G01N35/1095 ,  A61B5/14532 ,  A61B5/14557 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150824 ,  A61B5/153 ,  A61B5/157 ,  A61M1/3621 ,  A61M5/14 ,  A61M5/1415 ,  A61M2005/1404 ,  A61M2005/1726 ,  A61M2230/201 ,  B01L3/502 ,  B01L3/50273 ,  B01L3/52 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2400/0478 ,  B01L2400/0633 ,  G01N21/35

Abstract: A method of extracting and analyzing bodily fluids from a patient at the point of care for the patient is provided. The method comprises establishing fluid communication between an analyte detection system and a bodily fluid in the patient. A portion of the bodily fluid is drawn from the patient. A first component of the bodily fluid is separated from the drawn portion, while the analyte detection system remains in fluid communication with the patient. The analyte detection system analyzes the first component to measure a concentration of an analyte in an accurate and timely manner.

Abstract translation: 提供了在患者护理点从患者提取和分析体液的方法。 该方法包括在患者体内建立分析物检测系统和体液之间的流体连通。 体液的一部分从患者身上抽出。 分析物检测系统与患者保持流体连通，将体液的第一组分与拉出部分分离。 分析物检测系统分析第一个成分，以准确和及时的方式测量分析物的浓度。

公开(公告)号：US20070179436A1

公开(公告)日：2007-08-02

申请号：US11316684

申请日：2005-12-21

Applicant: James Braig ,  Peter Rule

Inventor： James Braig ,  Peter Rule

IPC: A61M37/00 ,  A61B5/00 ,  A61M31/00

CPC classification number: A61B5/1486 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61B2562/0295 ,  A61M5/14232 ,  A61M2005/1726 ,  A61M2230/201 ,  G01N27/3271 ,  G01N33/49

Abstract: An embodiment of a system for analyzing a body fluid of a patient comprises a fluid transport network that has a patient end configured to provide fluid communication with the body fluid in the patient and a fluid delivery point spaced from the patient end. A pump system is coupled to the fluid transport network. The pump system has an infusion mode in which the pump system is operable to pump an infusion fluid toward the patient end of the fluid transport network. The pump system has a draw mode in which the pump system is operable to draw the body fluid from the patient into the fluid transport network through the patient end. The system further comprises at least one fluid holder located near the fluid delivery point of the fluid transport network. The at least one fluid holder is positioned to receive a portion of the body fluid delivered to the delivery point by the fluid transport network. A laboratory-grade fluid analyzer is configured to receive the fluid holder and to measure at least one analyte in the portion of the body fluid.

Abstract translation: 用于分析患者体液的系统的实施例包括流体输送网络，其具有构造成提供与患者体液的流体连通的患者端和与患者端间隔开的流体输送点。 泵系统耦合到流体输送网络。 泵系统具有输液模式，其中泵系统可操作以将输注流体泵送到流体输送网络的患者端。 泵系统具有牵引模式，其中泵系统可操作以通过患者端将患者体液从患者吸入流体输送网络。 该系统还包括位于流体输送网络的流体输送点附近的至少一个流体保持器。 至少一个流体保持器被定位成接收由流体输送网络输送到输送点的体液的一部分。 实验室级流体分析器被配置为接收流体保持器并测量体液部分中的至少一种分析物。

公开(公告)号：US20070083143A1

公开(公告)日：2007-04-12

申请号：US11314731

申请日：2005-12-21

Applicant: James Braig ,  Richard Keenan

Inventor： James Braig ,  Richard Keenan

IPC: A61M37/00

CPC classification number: A61B5/157 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61M5/14212 ,  A61M2230/20 ,  G01N21/35

Abstract: A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow system. The system comprises a passageway, and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.

Abstract translation: 一种用于在体外血液流动系统中保持清晰通道的方法。 该方法包括间歇地向体外血液流通系统的通道提供一种或多种抗凝血剂。 还公开了一种体外血液流动系统。 该系统包括通道和可操作地连接以向所述通道的至少一部分提供一种或多种抗凝血剂的装置。

公开(公告)号：US20070083090A1

公开(公告)日：2007-04-12

申请号：US11316523

申请日：2005-12-21

Applicant: Bernhard Sterling ,  James Braig ,  Peter Rule ,  Richard King

Inventor： Bernhard Sterling ,  James Braig ,  Peter Rule ,  Richard King

IPC: A61B5/00

CPC classification number: G06F19/3468 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/1486 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61M5/14212 ,  A61M2230/20 ,  G01N21/274 ,  G01N21/35 ,  G01N2201/1293 ,  G06F19/00

Abstract: In certain embodiments, a method of maintaining health of a patient uses an analyte detection system. The analyte detection system is coupled to the patient such that a bodily fluid of the patient is accessible to the analyte detection system. The method includes automatically initiating and conducting a measurement of an analyte in the bodily fluid using the analyte detection system. The method further includes determining a treatment dose for the patient based on the measurement using the analyte detection system.

Abstract translation: 在某些实施例中，维持患者健康的方法使用分析物检测系统。 分析物检测系统耦合到患者，使得患者的体液可被分析物检测系统访问。 该方法包括使用分析物检测系统自动启动和进行体液中的分析物的测量。 该方法还包括基于使用分析物检测系统的测量确定患者的治疗剂量。

公开(公告)号：US20060268258A1

公开(公告)日：2006-11-30

申请号：US11337943

申请日：2006-01-23

Applicant: James Braig

Inventor： James Braig

IPC: G01N33/48

CPC classification number: A61B5/157 ,  A61B5/01 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150083 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150458 ,  A61B5/150503 ,  A61B5/150618 ,  A61B5/150717 ,  A61B5/15087 ,  A61B5/151 ,  A61B5/15107 ,  A61B5/15136 ,  A61B5/1514 ,  A61B5/15194 ,  A61B5/6826 ,  A61B5/6838 ,  A61B10/0045 ,  A61B2562/0295 ,  A61B2562/12 ,  G01N21/03 ,  G01N21/0332 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/3581 ,  G01N33/49 ,  G01N33/66 ,  G01N2021/0389 ,  G01N2201/02 ,  G01N2201/068

Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.

公开(公告)号：US20060200071A1

公开(公告)日：2006-09-07

申请号：US11314173

申请日：2005-12-21

Applicant: Bernhard Sterling ,  James Braig ,  Peter Rule ,  W. Hall ,  Mark Wechsler ,  Jennifer Gable

Inventor： Bernhard Sterling ,  James Braig ,  Peter Rule ,  W. Hall ,  Mark Wechsler ,  Jennifer Gable

IPC: A61M31/00 ,  A61B5/00

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M2205/12 ,  A61M2230/20 ,  A61M2230/201 ,  G01N1/14 ,  G01N21/05 ,  G01N21/274 ,  G01N21/35 ,  G01N2021/0346

Abstract: An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and at least one pump intermittently operable to draw a sample of bodily fluid from the patient. The apparatus further comprises a fluid analyzer positioned to analyze at least a portion of the sample and measure the presence of two or more analytes. Also disclosed is a method for analyzing the composition of a bodily fluid in a patient. The method comprises drawing a sample of the bodily fluid of the patient through a fluid handling network configured to maintain fluid communication with a bodily fluid in a patient. The method further comprises analyzing the at least a portion of the sample in a fluid analyzer to estimate the concentration of two or more analytes in the sample.

Abstract translation: 一种用于分析体液组成的装置。 该装置包括流体处理网络，其包括被配置为保持与患者体内的体液的流体连通的患者端以及间歇地可操作以从患者抽取体液样本的至少一个泵。 该装置还包括流体分析器，定位成分析样品的至少一部分并测量两种或多种分析物的存在。 还公开了一种用于分析患者体液组成的方法。 该方法包括通过流体处理网络来绘制患者的体液样本，流体处理网络被配置为保持患者体内与体液的流体连通。 该方法还包括在流体分析仪中分析样品的至少一部分以估计样品中两种或多种分析物的浓度。

公开(公告)号：US20060195058A1

公开(公告)日：2006-08-31

申请号：US11316685

申请日：2005-12-21

Applicant: Jennifer Gable ,  James Braig ,  Kenneth Witte ,  Mark Wechsler ,  Peng Zheng ,  Richard Keenan

Inventor： Jennifer Gable ,  James Braig ,  Kenneth Witte ,  Mark Wechsler ,  Peng Zheng ,  Richard Keenan

IPC: A61M31/00 ,  A61B5/00

CPC classification number: A61B5/157 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/4839 ,  A61B10/0064 ,  A61B2560/0443 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M5/1723 ,  A61M5/365 ,  A61M5/38 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2230/20 ,  A61M2230/201 ,  G01N21/03 ,  G01N21/3577 ,  G01N2021/3595 ,  G01N2201/02 ,  G01N2201/061 ,  Y10T137/4478 ,  Y10T137/7722 ,  Y10T137/86485 ,  Y10T436/111666 ,  Y10T436/2575

Abstract: A fluid handling and analysis system comprises a fluid transport network comprising at least a first fluid passageway. The fluid transport network includes a patient end that is configured to maintain fluid communication with a bodily fluid in a patient. A sample analysis chamber and waste container are each accessible via the fluid transport network. A pump unit is in operative engagement with the fluid transport network. The pump unit has an infusion mode in which the pump unit is operable to deliver an infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a volume of the bodily fluid from the patient through the patient end, towards the sample analysis chamber. A spectroscopic fluid analyzer is configured to analyze a sample of the bodily fluid while the sample is in the sample analysis chamber, and determine a concentration of at least one analyte. The fluid transport network and the pump unit are configured to draw a volume of the bodily fluid from the patient, isolate a fraction of the bodily fluid from the volume, and pass the fraction to the sample analysis chamber and then to the waste container.

Abstract translation: 流体处理和分析系统包括至少包括第一流体通道的流体输送网络。 流体输送网络包括被配置为保持患者体内与体液的流体连通的患者端。 样品分析室和废物容器均可通过流体输送网络接近。 泵单元与流体输送网络操作地接合。 泵单元具有输注模式，在该模式中，泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中，泵单元可操作以从患者抽取体积的体液 通过患者端，朝向样品分析室。 光谱流体分析器被配置为当样品在样品分析室中时分析体液样品，并确定至少一种分析物的浓度。 流体输送网络和泵单元被配置成从患者抽取体积的体液，将体液的一部分与体积隔离，并将分数通过样品分析室，然后传递到废物容器。

公开(公告)号：US20060195046A1

公开(公告)日：2006-08-31

申请号：US11316686

申请日：2005-12-21

Applicant: Bernhard Sterling ,  Jennifer Gable ,  James Braig ,  Mark Wechsler ,  Peng Zheng ,  Peter Rule ,  Richard Keenan

Inventor： Bernhard Sterling ,  Jennifer Gable ,  James Braig ,  Mark Wechsler ,  Peng Zheng ,  Peter Rule ,  Richard Keenan

IPC: A61B5/155

CPC classification number: A61B5/14546 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61M5/14212 ,  A61M2230/20 ,  G01N35/1095

Abstract: In certain embodiments, a method samples a body fluid of a patient. The method includes providing a fluid handling system having one or more fluid passageways. The method further includes infusing an infusion fluid by way of a fluid handling system into a patient through one or more fluid passageways. The method further includes obtaining a sample of body fluid by way of a fluid handling system from a patient through one or more fluid passageways. The obtained sample is no more than 400 microliters in volume. The method further includes analyzing at least an analyzed portion of the obtained sample by way of an analyte detection system operatively associated with the fluid handling system to determine a concentration of at least one analyte.

Abstract translation: 在某些实施方案中，方法对患者的体液进行取样。 该方法包括提供具有一个或多个流体通道的流体处理系统。 该方法还包括通过流体处理系统通过一个或多个流体通道将输注液输入患者体内。 该方法还包括通过来自患者的流体处理系统通过一个或多个流体通道获得体液样品。 所得样品的体积不超过400微升。 该方法还包括通过可操作地与流体处理系统相关联的分析物检测系统分析所获得的样品的至少一部分分析物，以确定至少一种分析物的浓度。

公开(公告)号：US20060194325A1

公开(公告)日：2006-08-31

申请号：US11316701

申请日：2005-12-21

Applicant: Jennifer Gable ,  James Braig ,  Kenneth Li ,  Mark Wechsler ,  Peng Zheng ,  Richard Keenan

Inventor： Jennifer Gable ,  James Braig ,  Kenneth Li ,  Mark Wechsler ,  Peng Zheng ,  Richard Keenan

IPC: G01N31/22

CPC classification number: A61B5/157 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/4839 ,  A61B10/0064 ,  A61B2560/0443 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M5/1723 ,  A61M5/365 ,  A61M5/38 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2230/20 ,  A61M2230/201 ,  G01N21/03 ,  G01N21/3577 ,  G01N2021/3595 ,  G01N2201/02 ,  G01N2201/061 ,  Y10T137/4478 ,  Y10T137/7722 ,  Y10T137/86485 ,  Y10T436/111666 ,  Y10T436/2575

Abstract: A fluid handling and analysis system is provided. The system includes a main analysis and control instrument and a fluid handling module that are removably engageable with the main instrument. The main instrument comprises a spectroscopic bodily fluid analyzer and at least one control element. The fluid handling module includes a spectroscopic sample cell and at least one fluid handling element, and the sample cell is accessible via the fluid handling element. The fluid handling element has a control interface configured to engage the control element when the main instrument and the fluid handling module are engaged.

Abstract translation: 提供流体处理和分析系统。 该系统包括可拆卸地与主仪器接合的主分析和控制仪器和流体处理模块。 主要仪器包括光谱体液分析仪和至少一个控制元件。 流体处理模块包括光谱样品池和至少一个流体处理元件，并且样品池可通过流体处理元件接近。 流体处理元件具有控制接口，该控制接口构造成当主仪器和流体处理模块接合时接合控制元件。