公开(公告)号：US06508379B1

公开(公告)日：2003-01-21

申请号：US09831644

申请日：2001-06-18

Applicant: Henriette Hermine Titia Van De Pol-Klein Nagelvoort ,  Jan Albert Henri Klein Nagelvoort ,  Alberthe Joan Klein Nagelvoort ,  Henri Jan Albert Klein Nagelvoort

Inventor： Henriette Hermine Titia Van De Pol-Klein Nagelvoort ,  Jan Albert Henri Klein Nagelvoort ,  Alberthe Joan Klein Nagelvoort ,  Henri Jan Albert Klein Nagelvoort

IPC: A47G1922

CPC classification number: A47G19/2272 ,  B65D47/2081

Abstract: A leak-free drinking beaker comprises a container as well as a lid closing the container, a drink opening which opens into the interior of the container, and a valve extending over the drink opening, which valve is held in the closed position under a certain pretension and can be released against said pretension under the influence of a pressure difference. The valve is a double-acting non-return valve and comprises a flexible valve element and two separate valve seats, the valve element and one of the valve seats has a blocking action in a direction opposed to the direction in which the valve element has a blocking action with the other valve seat.

Abstract translation: 一个无泄漏的饮用烧杯包括容器以及关闭容器的盖子，一个通向容器内部的饮料开口和一个在饮料开口上延伸的阀门，该阀门在一定的位置处保持在关闭位置 预压力可以在压力差的影响下抵抗所述预紧力而释放。 阀是双作用止回阀，包括柔性阀元件和两个单独的阀座，阀元件和阀座中的一个在与阀元件具有的方向相反的方向上具有阻塞作用 与另一个阀座阻塞作用。

公开(公告)号：US20170252324A1

公开(公告)日：2017-09-07

申请号：US15449488

申请日：2017-03-03

Applicant: JEFFREY ALAN KLEIN ,  PAYTRA ALAN KLEIN ,  BRAM ALAN KLEIN

Inventor： Jeffrey Alan Klein ,  Paytra Alan Klein ,  Bram Alan Klein

IPC: A61K31/404 ,  A61K9/08 ,  A61K31/167 ,  A61M5/178 ,  A61K9/00 ,  A61K47/02 ,  A61M5/145 ,  A61K31/137 ,  A61K45/06

Abstract: A tumescent contravenom solution including: (a) a vasoconstrictor, (b) a physiological crystalloid solution, and (c) optionally a contravenom agent that neutralizes tissue toxic enzymes present in a venom and/or a drug that impairs or paralyzes lymphatic smooth muscle function and impairs lymphatic transport of venom. Also described are methods of treating an envenomation in a subject, and a kit for performing the method of treating an envenomation.

公开(公告)号：US1470925A

公开(公告)日：1923-10-16

申请号：US50952621

申请日：1921-10-22

Applicant: EUGENE KLEIN ,  SAMUEL KLEIN ,  MORRIS KLEIN

Inventor： EUGENE KLEIN ,  SAMUEL KLEIN ,  MORRIS KLEIN

IPC: A47G25/36

CPC classification number: A47G25/36

公开(公告)号：USD763573S1

公开(公告)日：2016-08-16

申请号：US29509982

申请日：2014-11-24

Applicant: Julia Hope Klein ,  Jerald Leroy Klein

Designer： Julia Hope Klein ,  Jerald Leroy Klein

公开(公告)号：US20090194556A1

公开(公告)日：2009-08-06

申请号：US12367236

申请日：2009-02-06

Applicant: Seth A. Klein ,  Michael R. Klein

Inventor： Seth A. Klein ,  Michael R. Klein

IPC: B65D83/04 ,  B65H3/56

CPC classification number: B65D83/0409 ,  B65D50/062

Abstract: A pill dispensing cap that secures to a conventional pill container. The pill dispensing cap has a lower cap, a pill discharge port, and a spring loaded rotatable and slidable upper cap. Pills are dispensed one at a time, and the remaining pills are isolated from external contamination. A child resistant lock prevents small children and/or mentally handicapped individuals from easily accessing medicine inside the container. The child resistant lock uses a vertically slidable upper cap that is slidably and rotatably attached to the lower cap. A child safety lock uses a key in the upper cap that must be aligned with a slot in the lower cap to allow a pill to be dispensed. When the key and slot are aligned, the upper cap is vertically compressed against the lower cap. As the upper cap moves toward the base cap, a gravity fed pill discharge port is exposed which releases a single pill.

Abstract translation: 药丸分配帽，固定到常规药丸容器。 药丸分配帽具有下盖，药丸排出口和弹簧加载的可旋转和可滑动的上盖。 药片一次分配一次，剩余的药丸与外部污染物分离。 儿童防护锁可防止小孩和/或弱智人士容易地进入集装箱内的药物。 防儿童锁使用可滑动和可旋转地附接到下盖的可垂直滑动的上盖。 儿童安全锁使用上盖中的一个必须与下盖中的槽对齐的钥匙，以允许药丸被分配。 当键和槽对齐时，上盖相对于下盖垂直压缩。 当上盖向基盖移动时，暴露重力进料药丸排出口，释放单个药丸。

公开(公告)号：US20080236857A1

公开(公告)日：2008-10-02

申请号：US11695291

申请日：2007-04-02

Applicant: David T. KLEIN ,  Donald M. Klein

Inventor： David T. KLEIN ,  Donald M. Klein

IPC: H02G1/00 ,  H05K5/00

CPC classification number: H02G1/00 ,  Y10T29/49982

Abstract: The present invention is directed to a method and system for preventing intrusion of viscous poured concrete into electrical or telecom boxes using resilient members having a top surface that fills the surface opening of the box it is inserted into where the spring back of the resilient member insures a proper seal around the surface opening. An example method for preventing intrusion of poured concrete into a box comprises selecting a suitable member for insertion into the box, compressing the member, inserting it into the box, and pouring concrete around the box. The resilient member may subsequently be removed and reused in another box. In another example method, a supply of resilient members of different shapes and sizes is provided for insertion into differently sized boxes.

Abstract translation: 本发明涉及一种用于防止将粘性浇注混凝土侵入电气或电信箱的方法和系统，该弹性构件具有顶部表面，该顶面填充其被插入弹性构件的弹簧背面的盒子的表面开口， 围绕表面开口的适当密封。 防止浇注混凝土侵入箱体中的一种示例性方法包括选择合适的构件以插入箱体，压缩构件，将其插入箱体中，并将​​混凝土浇注在箱体周围。 弹性构件可以随后被移除并重新用于另一个盒子中。 在另一个示例性方法中，提供不同形状和尺寸的弹性构件的供应用于插入到不同尺寸的盒中。

公开(公告)号：US20080047462A1

公开(公告)日：2008-02-28

申请号：US11596143

申请日：2005-03-10

Applicant: Howard Klein ,  Duy Klein ,  Christopher Whewell

Inventor： Howard Klein ,  Duy Klein ,  Christopher Whewell

IPC: C08L63/00 ,  C08L39/00 ,  C08L63/02 ,  C09D11/10

CPC classification number: B01F17/0042 ,  B01F17/005 ,  B01F17/0085 ,  C08G59/50 ,  C09D11/03 ,  C09D11/326 ,  C09D11/36

Abstract: Provided herein are compositions useful as ink which contain novel dispersants that are capable of dispersing pigments which are traditionally difficult to disperse while maintaining acceptable levels of viscosity. Use of dispersants as taught herein enables the preparation of a wide variety of inks having high pigment loading and existing within a conventionally useful viscosity range.

Abstract translation: 本文提供了可用作油墨的组合物，其含有新型分散剂，其能够分散传统上难以分散的颜料，同时保持可接受的粘度水平。 使用如本文所述的分散剂能够制备具有高颜料负载并存在于常规有用的粘度范围内的各种各样的油墨。

公开(公告)号：US07127972B2

公开(公告)日：2006-10-31

申请号：US10382285

申请日：2003-03-05

Applicant: David T. Klein ,  Donald M. Klein

Inventor： David T. Klein ,  Donald M. Klein

IPC: B25G1/00

CPC classification number: B23B51/126 ,  B25B13/481 ,  B25B23/0021 ,  B25B23/0035 ,  B25B31/00

Abstract: An apparatus for facilitating the placement of a rod member into a remote surface, comprising: an elongated hollow tube member having a first end and a second end; the first end of the elongated hollow tube member adapted to receive and removably secure a drill bit with the drill bit projecting from the end of the tube member; the first end of the elongated hollow tube member further adapted to receive and removably secure an anchor with the rod member projecting therefrom, the rod member being of a length less than the elongated tube member and having a greatest outer diameter less than the inner diameter of the elongated tube member; and the second end of the elongated hollow tube member adapted to be mounted in a driving apparatus.

Abstract translation: 一种用于促进杆构件放置在远程表面中的装置，包括：细长的中空管构件，其具有第一端和第二端; 所述细长中空管件的第一端适于接纳和可移除地固定钻头，所述钻头从所述管件端部突出; 细长中空管构件的第一端还适于容纳和可移除地固定具有从其突出的杆构件的锚固件，杆构件的长度小于细长管构件，并且具有小于内径的最大外径 细长管件; 并且细长中空管构件的第二端适于安装在驱动装置中。

公开(公告)号：US06833060B2

公开(公告)日：2004-12-21

申请号：US09850540

申请日：2001-05-07

Applicant: George Harding ,  Elias Klein ,  Jon Klein

Inventor： George Harding ,  Elias Klein ,  Jon Klein

IPC: G01N27453

CPC classification number: G01N27/44704 ,  G01N27/44773

Abstract: The present invention relates generally to the electrophoretic separation of biomolecules, including but not limited to proteins, peptides, DNA and RNA. The methods of this invention are particularly useful when applied to two-dimensional gel electrophoresis.

Abstract translation: 本发明一般涉及生物分子的电泳分离，包括但不限于蛋白质，肽，DNA和RNA。 当应用于二维凝胶电泳时，本发明的方法特别有用。

公开(公告)号：US6165996A

公开(公告)日：2000-12-26

申请号：US104695

申请日：1998-06-25

Applicant: Harry S Winchell ,  Joseph Y Klein ,  Elliot D Simhon ,  Rosa L Cyjon ,  Ofer Klein ,  Haim Zaklad

Inventor： Harry S Winchell ,  Joseph Y Klein ,  Elliot D Simhon ,  Rosa L Cyjon ,  Ofer Klein ,  Haim Zaklad

IPC: G01R33/28 ,  A61B5/055 ,  A61K31/13 ,  A61K31/131 ,  A61K31/132 ,  A61K31/133 ,  A61K31/135 ,  A61K31/136 ,  A61K31/137 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/407 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4985 ,  A61K31/551 ,  A61K31/663 ,  A61K31/675 ,  A61K47/48 ,  A61K49/00 ,  A61K49/04 ,  A61K49/06 ,  A61K51/04 ,  A61P3/00 ,  A61P7/00 ,  A61P17/00 ,  A61P17/02 ,  A61P19/10 ,  A61P29/00 ,  A61P31/00 ,  A61P31/04 ,  A61P31/10 ,  A61P31/14 ,  A61P35/00 ,  A61P37/06 ,  A61P39/04 ,  A61P39/06 ,  C07C215/14 ,  C07D255/02 ,  C07D255/04 ,  C07D257/00 ,  C07D257/02 ,  C07D403/14 ,  C07D405/14 ,  C07D487/04 ,  C07D487/08 ,  C07D487/10 ,  C07D487/22 ,  C07F9/6515 ,  C07F9/6524 ,  C07F9/6561 ,  C09K3/00 ,  G01N24/08 ,  C07B47/00

CPC classification number: C07D405/14 ,  A61K31/13 ,  A61K31/131 ,  A61K31/135 ,  A61K31/136 ,  A61K31/137 ,  A61K31/395 ,  A61K31/4025 ,  A61K31/415 ,  A61K31/44 ,  A61K31/675 ,  A61K47/54 ,  A61K47/547 ,  A61K49/0002 ,  A61K49/04 ,  A61K49/06 ,  A61K51/0478 ,  A61K51/0482 ,  C07D255/02 ,  C07D255/04 ,  C07D257/00 ,  C07D403/14 ,  C07D487/08 ,  C07D487/10 ,  C07F9/6515 ,  C07F9/6524 ,  C07F9/6561 ,  Y10S514/836

Abstract: This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease in the in vivo bioavailability of first transition series elements and/or removal from the body of first transition series elements and elements with similar chemical properties. These characteristics make such compounds useful in the management of diseases associated with a bodily excess of first transition series elements and elements with similar chemical properties. This invention demonstrates that such compounds inhibit mammalian, bacterial, and fungal cell replication and are therefore useful in the treatment of neoplasia, infection, inflammation, immune reponse, and in termination of pregnancy. Since these compounds are capable of descreasing the in vivo availability of tissue iron they are useful in management of free radical mediated tissue damage, and oxidation mediated tissue damage. When combined with radioisotopic or paramagnetic cations of first transition series elements, or elements with chemical properties similar to those of first transition series elements, prior to their administration, the resulting complexes are useful as diagnostic agents in nuclear medicine and magnetic resonance imaging (MRI).

Abstract translation: 本发明涉及合成和使用具有螯合亲和性和对第一转变序列元件的选择性的一类化合物。 施用游离或缀合的化合物或游离或缀合的化合物的生理盐导致第一过渡系列元件的体内生物利用度降低和/或从具有相似化学性质的第一过渡系列元件和元件的体内去除。 这些特征使得这些化合物可用于治疗与具有相似化学性质的第一过渡系列元件和元件的身体过剩相关的疾病。 本发明证明这些化合物抑制哺乳动物，细菌和真菌细胞复制，因此可用于治疗肿瘤形成，感染，炎症，免疫反应和终止妊娠。 由于这些化合物能够降低组织铁的体内可利用性，因此它们可用于管理自由基介导的组织损伤和氧化介导的组织损伤。 当与第一过渡系列元件的放射性同位素或顺磁性阳离子或具有与第一过渡系列元件类似的化学特性的元素组合时，在其给药之前，所得复合物可用作核医学和磁共振成像（MRI）中的诊断剂， 。