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公开(公告)号:US07157245B2
公开(公告)日:2007-01-02
申请号:US09942583
申请日:2001-08-31
申请人: Andrew Robinson , Andrew Richard Gorringe , Michael John Hudson , Philippa Bracegirdle , John Simon Kroll , Paul Richard Langford , Steven Anthony Rochford Webb , Keith Cartwright , Cliona Anne O'Dwyer , Karen Margaret Reddin
发明人: Andrew Robinson , Andrew Richard Gorringe , Michael John Hudson , Philippa Bracegirdle , John Simon Kroll , Paul Richard Langford , Steven Anthony Rochford Webb , Keith Cartwright , Cliona Anne O'Dwyer , Karen Margaret Reddin
CPC分类号: C07K14/22 , A61K39/095 , A61K39/12 , A61K39/165 , A61K2039/505 , A61K2039/521 , A61K2039/523 , A61K2039/55566 , Y02A50/412
摘要: Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria which express genes from virulent strains of Neisseria and/or heterologous gene products from non-neisserial sources. Such compositions are used in vaccine preparations for the treatment of microbial infection.
摘要翻译: 用于治疗微生物感染,特别是脑膜炎球菌疾病的方法和组合物包含共生奈瑟氏球菌或共生的奈瑟氏球菌的提取物。 其他方法和组合物包含共表达奈瑟氏球菌,其表达来自奈瑟氏球菌的毒性菌株的基因和/或来自非奈及利亚源的异源基因产物。 这种组合物用于治疗微生物感染的疫苗制剂中。
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公开(公告)号:US20120101185A1
公开(公告)日:2012-04-26
申请号:US13265601
申请日:2010-04-16
CPC分类号: A61L27/18 , A61L27/446 , C08L71/00
摘要: The use of barium sulphate for increasing the impact strength of a polyaryletherketone and/or a polyarylethersulphone involves compounding the barium sulphate with the polymeric material and including water in the composition prepared. The material may be used in implantable prostheses.
摘要翻译: 使用硫酸钡来增加聚芳醚酮和/或聚芳醚砜的冲击强度包括在制备的组合物中将硫酸钡与聚合物材料混合并包括水。 该材料可用于可植入的假体。
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公开(公告)号:US07081244B2
公开(公告)日:2006-07-25
申请号:US10185769
申请日:2002-07-01
申请人: Andrew Robinson , Andrew Richard Gorringe , Michael John Hudson , Philippa Bracegirdle , John Simon Kroll , Paul Richard Langford , Steven Anthony Rochford Webb , Keith Cartwright , Cliona Anne O'Dwyer
发明人: Andrew Robinson , Andrew Richard Gorringe , Michael John Hudson , Philippa Bracegirdle , John Simon Kroll , Paul Richard Langford , Steven Anthony Rochford Webb , Keith Cartwright , Cliona Anne O'Dwyer
IPC分类号: A61K39/02 , A61K39/095 , A61K39/116 , A61K39/38 , C07K1/00
CPC分类号: A61K39/165 , A61K39/095 , A61K39/12 , A61K2039/505 , A61K2039/521 , A61K2039/523 , C07K14/22 , Y10S530/825
摘要: Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise conimensal Neisseria which express genes from virulent strains of Neisseria and/or heterologous gene products from non-Neisserial sources. Such compositions are used in vaccine preparations for the treatment of microbial infection.
摘要翻译: 用于治疗微生物感染,特别是脑膜炎球菌疾病的方法和组合物包含共生奈瑟氏球菌或共生的奈瑟氏球菌的提取物。 其他方法和组合物包括表达从奈瑟氏球菌毒性菌株和/或非奈瑟氏菌来源的异源基因产物的基因的相关奈瑟氏球菌。 这种组合物用于治疗微生物感染的疫苗制剂中。
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公开(公告)号:US20140035201A1
公开(公告)日:2014-02-06
申请号:US13985457
申请日:2012-02-14
申请人: Marcus Jarman-Smith , Mark Brady , John Devine , Keith Cartwright
发明人: Marcus Jarman-Smith , Mark Brady , John Devine , Keith Cartwright
IPC分类号: B29C45/00
CPC分类号: B29C45/0001 , A61L27/46 , C08J3/201 , C08J3/203 , C08J9/0066 , C08J9/26 , C08J2201/0444 , C08J2207/10 , C08J2371/12 , C08K3/32 , C08K2003/325 , C08L71/00
摘要: There are provided methods of producing a component incorporating a bioactive material. In one embodiment the method comprises: (a) using a screw extruder to mix a polymeric material (I) with a bioactive material (II) and melt the polymeric material (I); and (b) making a component by moulding; and wherein the polymeric material (I) is of a type which includes: (i) phenyl moieties; (ii) ketone moieties; and (iii) ether moieties. Also provided are components comprising a polymeric material and a bioactive material.
摘要翻译: 提供了生产包含生物活性材料的组分的方法。 在一个实施方案中,该方法包括:(a)使用螺杆挤出机将聚合材料(I)与生物活性材料(II)混合并熔化聚合材料(I); 和(b)通过模塑制成组分; 并且其中所述聚合物材料(I)是一种类型,其包括:(i)苯基部分; (ii)酮部分; 和(iii)醚部分。 还提供了包含聚合物材料和生物活性材料的组分。
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公开(公告)号:US20050169943A1
公开(公告)日:2005-08-04
申请号:US11056199
申请日:2005-02-14
申请人: Andrew Robinson , Andrew Gorringe , Michael Hudson , Philippa Bracegirdle , John Kroll , Paul Langford , Steven Webb , Keith Cartwright , Cliona O'Dwyer
发明人: Andrew Robinson , Andrew Gorringe , Michael Hudson , Philippa Bracegirdle , John Kroll , Paul Langford , Steven Webb , Keith Cartwright , Cliona O'Dwyer
IPC分类号: A61K39/095 , A61K39/165 , A61P31/04 , C07K14/22 , C12N1/21 , C12N15/31
CPC分类号: A61K39/165 , A61K39/095 , A61K39/12 , A61K2039/505 , A61K2039/521 , A61K2039/523 , C07K14/22 , Y10S530/825
摘要: Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria which express genes from virulent strains of Neisseria and/or heterologous gene products from non-Neisserial sources. Such compositions are used in vaccine preparations for the treatment of microbial infection.
摘要翻译: 用于治疗微生物感染,特别是脑膜炎球菌疾病的方法和组合物包含共生奈瑟氏球菌或共生的奈瑟氏球菌的提取物。 其他方法和组合物包含共表达的奈瑟氏球菌,其表达来自奈奈瑟氏球菌的毒性菌株的基因和/或来自非奈瑟氏菌来源的异源基因产物。 这种组合物用于治疗微生物感染的疫苗制剂中。
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