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    Anthrax antigenic compositions
    3.
    发明申请
    Anthrax antigenic compositions 审中-公开
    炭疽抗原组合物

    公开(公告)号：US20050112145A1

    公开(公告)日：2005-05-26

    申请号：US10494384

    申请日：2002-11-01

    申请人： Michael Hudson ,  Andrew Robinson ,  Nigel Silman ,  Bassam Hallis ,  Charles Penn

    发明人： Michael Hudson ,  Andrew Robinson ,  Nigel Silman ,  Bassam Hallis ,  Charles Penn

    IPC分类号： C12N15/09 ,  A61K39/02 ,  A61K39/07 ,  A61K48/00 ,  A61P31/04 ,  C12N15/31 ,  C12P21/02

    CPC分类号： A61K39/07

    摘要： An antigenic pharmaceutical composition is provided comprising Protective Antigen (PA) and Lethal Factor (LF), wherein said PA and/or LF lacks a functional binding site, thereby preventing said PA and LF from binding together via said binding site or thereby preventing said PA from binding to a native PA cell receptor via said binding site, and wherein said composition is substantially non-toxic to animal cells. The composition is for preventing or minimising anthrax toxicity in mammals, preferably in humans. Also provided are DNA and RNA based vaccines encoding the antigenic components of said pharmaceutical composition. The present specification also describes antibodies that bind to at least one of PA, LF or EF, which binding thereby prevents:—(i) PA from binding to LF or EF, or to a native PA cell receptor; or (ii) LF from binding to PA; or (iii) EF from binding to PA.

    摘要翻译： 提供了包含保护性抗原（PA）和致死因子（LF）的抗原性药物组合物，其中所述PA和/或LF缺少功能性结合位点，从而防止所述PA和LF通过所述结合位点结合在一起，从而防止所述PA 通过所述结合位点与天然PA细胞受体结合，并且其中所述组合物对动物细胞基本上无毒性。 该组合物用于预防或最小化哺乳动物中的炭疽毒性，优选在人体内。 还提供了编码所述药物组合物的抗原成分的基于DNA和RNA的疫苗。 本说明书还描述了结合至少一种PA，LF或EF的抗体，其结合从而防止： - （i）PA结合LF或EF或天然PA细胞受体; 或（ii）LF结合PA; 或（iii）EF结合PA。

    Method and apparatus for a loudspeaker assembly
    4.
    发明授权
    Method and apparatus for a loudspeaker assembly 有权
    扬声器组件的方法和装置

    公开(公告)号：US08439153B2

    公开(公告)日：2013-05-14

    申请号：US13564947

    申请日：2012-08-02

    申请人： Michael Hudson ,  William C Stewart, Jr. ,  Larry Frerichs

    发明人： Michael Hudson ,  William C Stewart, Jr. ,  Larry Frerichs

    IPC分类号： H04R1/02

    CPC分类号： H04R5/00 ,  H04R1/02 ,  H04R1/023 ,  H04R2201/021 ,  H04R2201/029 ,  Y10T29/4957

    摘要： The present invention relates to a loudspeaker assembly and a method of assembling a loudspeaker assembly. In one or more embodiments, the invention comprises forming a front baffle comprising a first driver mounting portion, an intermediate portion, and an edge mounting portion. A first driver is installed in the first driver mounting portion proximate to a first driver aperture. A rear baffle is formed from a second material, which, in one or more embodiments, is less stiff than the first material from which the front baffle is formed. The rear baffle comprises a top portion, sidewalls, a recessed mounting portion, and an edge portion. The edge mounting portion of the front baffle is attached to the recessed mounting portion of the rear baffle such that an entirety of said front baffle is recessed within said rear baffle spaced apart from said open bottom portion.

    摘要翻译： 扬声器组件及组装扬声器组件的方法技术领域本发明涉及扬声器组件和组装扬声器组件的方法。 在一个或多个实施例中，本发明包括形成包括第一驱动器安装部分，中间部分和边缘安装部分的前挡板。 第一驱动器安装在靠近第一驱动器孔的第一驱动器安装部分中。 后挡板由第二材料形成，在一个或多个实施例中，第二材料的硬度比形成前挡板的第一材料硬。 后挡板包括顶部，侧壁，凹入的安装部分和边缘部分。 前挡板的边缘安装部分附接到后挡板的凹入的安装部分，使得所述前挡板的整体在与所述开口底部间隔开的所述后挡板内凹入。

    Ceiling loudspeaker system
    5.
    发明授权
    Ceiling loudspeaker system 有权
    吊顶扬声器系统

    公开(公告)号：US08286749B2

    公开(公告)日：2012-10-16

    申请号：US13159801

    申请日：2011-06-14

    申请人： William Cameron Stewart, Jr. ,  Michael Hudson ,  Larry Frerichs ,  Clinton Strong ,  Weldon Gammon

    发明人： William Cameron Stewart, Jr. ,  Michael Hudson ,  Larry Frerichs ,  Clinton Strong ,  Weldon Gammon

    IPC分类号： H05K5/00

    CPC分类号： H04R1/025 ,  H04R1/2811 ,  H04R31/006 ,  H04R2201/021

    摘要： The present invention comprises a method and apparatus for installing a tile-mounted ceiling speaker that combines the ease of installation of a lay-in speaker system with the visual appearance of a tile-mounted speaker system. In one or more embodiments, the apparatus of the present invention includes a support frame and back box assembly configured for installation on top of a ceiling tile and a loudspeaker cartridge configured to be mounted to the support frame through an appropriately-sized hole in the ceiling tile. In one or more embodiments, the method of the present invention comprises forming an appropriately-sized hole in a ceiling tile, laying an integrated back box and support frame on top of the ceiling tile, connecting wires from an external audio source to terminals provided at the back box, connecting wires provided on the inside of the back box to a loudspeaker cartridge, inserting the loudspeaker cartridge into the hole in the ceiling tile from below, fastening the loudspeaker cartridge to the support frame, and fastening a grille to the loudspeaker cartridge. In one or more embodiments, a variety of interchangeable loudspeaker cartridges having differing loudspeaker configurations are provided. In one or more embodiments, the support frame and back box assembly is configured to allow installation of more than one loudspeaker cartridge. In one or more embodiments, the loudspeaker cartridges are configured for use both with a back box and without back box.

    摘要翻译： 本发明包括一种安装瓦片式天花板扬声器的方法和装置，其结合了将内置扬声器系统的安装的容易性与瓦片式扬声器系统的视觉外观。 在一个或多个实施例中，本发明的装置包括支撑框架和后箱组件，其被配置为安装在天花板瓦片的顶部上，扬声器盒被构造成通过天花板中适当尺寸的孔安装到支撑框架 瓦。 在一个或多个实施例中，本发明的方法包括在天花板瓦片中形成适当尺寸的孔，在天花板瓦片的顶部铺设集成的后箱和支撑框架，将外部音频源的导线连接到 后箱，将背箱内侧的连接线连接到扬声器盒，将扬声器盒从下方插入天花板瓦片中的孔中，将扬声器盒紧固到支撑框架上，并将格栅固定到扬声器盒 。 在一个或多个实施例中，提供了具有不同扬声器配置的各种可互换扬声器盒。 在一个或多个实施例中，支撑框架和后箱组件被配置为允许安装多于一个扬声器盒。 在一个或多个实施例中，扬声器盒配置成与背箱和没有后盒一起使用。

    Method and apparatus for a loudspeaker assembly
    6.
    发明授权
    Method and apparatus for a loudspeaker assembly 有权
    扬声器组件的方法和装置

    公开(公告)号：US08276706B2

    公开(公告)日：2012-10-02

    申请号：US13023345

    申请日：2011-02-08

    申请人： Michael Hudson ,  William C. Stewart, Jr. ,  Larry Frerichs

    发明人： Michael Hudson ,  William C. Stewart, Jr. ,  Larry Frerichs

    IPC分类号： H04R1/02

    CPC分类号： H04R5/00 ,  H04R1/02 ,  H04R1/023 ,  H04R2201/021 ,  H04R2201/029 ,  Y10T29/4957

    摘要： The present invention relates to a loudspeaker assembly and a method of assembling a loudspeaker assembly, comprising forming a front baffle, a first driver mounting portion, an intermediate portion, and an edge mounting portion. A port aperture formed in the intermediate portion, and a first driver installed in the first driver mounting portion. A rear baffle comprises a top portion, sidewalls, a recessed mounting portion, an edge portion and an electrical assembly. The edge mounting portion of the front baffle is attached to the recessed mounting portion of the rear baffle, and the rear baffle is secured to the back of the first driver. A back box is placed over the rear baffle provides thermal insulation, and a mounting plate securely attaches the first driver to a structural support. A perforated grille is crimped to the edge portion of the rear baffle and an edge portion of the back box.

    摘要翻译： 本发明涉及扬声器组件和组装扬声器组件的方法，包括形成前挡板，第一驱动器安装部分，中间部分和边缘安装部分。 形成在中间部分中的端口孔，以及安装在第一驱动器安装部分中的第一驱动器。 后挡板包括顶部，侧壁，凹入的安装部分，边缘部分和电组件。 前挡板的边缘安装部分附接到后挡板的凹入安装部分，后挡板固定到第一驱动器的后部。 后挡板放置在后挡板上，提供绝热，并且安装板将第一驱动器牢固地附接到结构支撑。 多孔格栅被卷曲到后挡板的边缘部分和背箱的边缘部分。

    METHOD AND APPARATUS FOR A LOUDSPEAKER ASSEMBLY
    7.
    发明申请
    METHOD AND APPARATUS FOR A LOUDSPEAKER ASSEMBLY 有权
    扬声器装配的方法和装置

    公开(公告)号：US20120186902A1

    公开(公告)日：2012-07-26

    申请号：US13355430

    申请日：2012-01-20

    申请人： William Cameron Stewart, JR. ,  Andrew C. Edwards ,  Michael Hudson ,  Andrew Evans

    发明人： William Cameron Stewart, JR. ,  Andrew C. Edwards ,  Michael Hudson ,  Andrew Evans

    IPC分类号： H05K5/00

    CPC分类号： H04R1/2865 ,  H04R1/023 ,  H04R2201/021 ,  Y10T29/49005

    摘要： A loudspeaker assembly is provided. In one or more embodiments the loudspeaker assembly comprises a perforated grille, a three dimensional loudspeaker frame to which a speaker driver is mounted, and a rear baffle. In one or more embodiments, the loudspeaker frame and rear baffle define a controlled volume around the speaker driver. In one or more embodiments the controlled volume comprises a driver cavity and a horn cavity in communication with the driver cavity and a port aperture.

    摘要翻译： 提供扬声器组件。 在一个或多个实施例中，扬声器组件包括穿孔格栅，扬声器驱动器所安装的三维扬声器框架和后挡板。 在一个或多个实施例中，扬声器框架和后挡板限定扬声器驱动器周围的受控体积。 在一个或多个实施例中，受控体积包括与驱动器腔和端口孔连通的驱动器腔和喇叭腔。

    System and methods of performing real-time on-board automotive telemetry analysis and reporting
    9.
    发明申请
    System and methods of performing real-time on-board automotive telemetry analysis and reporting 审中-公开
    执行实时车载汽车遥测分析和报告的系统和方法

    公开(公告)号：US20060229777A1

    公开(公告)日：2006-10-12

    申请号：US11401831

    申请日：2006-04-11

    申请人： Michael Hudson ,  Kelly McArthur

    发明人： Michael Hudson ,  Kelly McArthur

    IPC分类号： G01M17/00

    CPC分类号： G07C5/008 ,  G01M15/05 ,  G05B23/021 ,  G06F11/0739 ,  G07C5/085

    摘要： Active diagnosis of current operating and potential fault conditions in the operation of the vehicle is implemented using a diagnostic controller interoperating with an on-board vehicle control system as installed within a vehicle. The diagnostic controller supports autonomous execution of diagnostic tests initiated dependent on the operational state of the vehicle. The control system includes a diagnostics control manager that autonomously selects test routines for execution at defined operational states, including in-service operational states, a monitor, responsive to sensor data retrieved in real-time from the on-board vehicle control system, operative to detect a current instance of the in-service operational state of the vehicle, and a diagnostic test scheduler operative to initiate execution of the diagnostic test routine upon detection of the current instance of the in-service operational state of the vehicle.

    摘要翻译： 使用与安装在车辆内的车载车辆控制系统互操作的诊断控制器来实现车辆操作中的当前操作和潜在故障状况的主动诊断。 诊断控制器支持根据车辆的运行状态启动的诊断测试的自主执行。 控制系统包括诊断控制管理器，其自动选择用于在所定义的操作状态（包括在役操作状态）执行的测试例程，响应于从车载车辆控制系统实时检索的传感器数据的监视器，操作到 检测车辆的在役操作状态的当前实例，以及诊断测试调度器，用于在检测到车辆的在役操作状态的当前实例时启动诊断测试例程的执行。

    Method and apparatus for a loudspeaker assembly
    10.
    发明授权
    Method and apparatus for a loudspeaker assembly 有权
    扬声器组件的方法和装置

    公开(公告)号：US08720640B2

    公开(公告)日：2014-05-13

    申请号：US13898059

    申请日：2013-05-20

    申请人： William C. Stewart, Jr. ,  Andrew C. Edwards ,  Michael Hudson ,  Andrew Evans

    发明人： William C. Stewart, Jr. ,  Andrew C. Edwards ,  Michael Hudson ,  Andrew Evans

    IPC分类号： H05K5/00

    CPC分类号： H04R1/02 ,  H04R1/023 ,  H04R1/2865 ,  H04R2201/021

    摘要： A method and apparatus for providing a loudspeaker assembly is provided. In accordance with at least one embodiment, apparatus is provided comprising a ground plane, a loudspeaker driver mounted in a loudspeaker driver aperture of the ground plane, and a grille positioned relative to the ground plane such that a distance between the grille and the ground plane decreases with increasing distance from the loudspeaker driver. The loudspeaker assembly can be used to replace ceiling tiles having any size or configuration, and can also me mounted in other surfaces, such as ceiling walls, floors, table tops, etc. made of drywall, hard decking, wood, stone, cement, glass, or any other material or type of construction, or configured in a stand-alone loudspeaker frame or cabinet. The loudspeaker assembly of the present invention can be mounted in any orientation.

    摘要翻译： 提供一种用于提供扬声器组件的方法和装置。 根据至少一个实施例，提供了包括接地平面，安装在接地平面的扬声器驱动器孔中的扬声器驱动器和相对于接地平面定位的格栅的装置，使得格栅和接地平面之间的距离 随着与扬声器驱动器的距离增加而减小。 扬声器组件可以用于替换具有任何尺寸或构造的天花板瓦片，并且还可以将其安装在其他表面，例如由干墙，硬地板，木材，石头，水泥等制成的顶壁，地板，桌面等。 玻璃或任何其他材料或类型的结构，或配置在独立的扬声器框架或机柜中。 本发明的扬声器组件可以以任何方向安装。