PEPTIDE-BASED COMPOUNDS AS INHIBITORS OF NEUROTRANSMITTER SECRETION
    2.
    发明申请
    PEPTIDE-BASED COMPOUNDS AS INHIBITORS OF NEUROTRANSMITTER SECRETION 有权
    基于肽的化合物作为神经递质分泌物的抑制剂

    公开(公告)号:US20140286885A1

    公开(公告)日:2014-09-25

    申请号:US14356387

    申请日:2012-11-07

    IPC分类号: A61K8/64 A61Q19/08

    摘要: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

    摘要翻译: 本公开涉及基于肽的化合物,其衍生物,药学上可接受的盐,溶剂合物和水合物。 本公开的化合物和组合物可以抑制作为皱纹治疗的神经递质释放和肌肉收缩。 本公开的化合物可用于病理性神经元胞吐作用介导的化妆品和/或治疗目的。

    Peptide-based compounds as inhibitors of neurotransmitter secretion
    3.
    发明授权
    Peptide-based compounds as inhibitors of neurotransmitter secretion 有权
    基于肽的化合物作为神经递质分泌的抑制剂

    公开(公告)号:US09248089B2

    公开(公告)日:2016-02-02

    申请号:US14356387

    申请日:2012-11-07

    摘要: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

    摘要翻译: 本公开涉及基于肽的化合物,其衍生物,药学上可接受的盐,溶剂合物和水合物。 本公开的化合物和组合物可以抑制作为皱纹治疗的神经递质释放和肌肉收缩。 本公开的化合物可用于病理性神经元胞吐作用介导的化妆品和/或治疗目的。

    APPARATUS FOR PROCESSING BIOLOGICAL SAMPLES AND METHOD THEREOF
    5.
    发明申请
    APPARATUS FOR PROCESSING BIOLOGICAL SAMPLES AND METHOD THEREOF 审中-公开
    用于处理生物样品的装置及其方法

    公开(公告)号:US20130203072A1

    公开(公告)日:2013-08-08

    申请号:US13879995

    申请日:2010-10-29

    IPC分类号: G01N1/31

    摘要: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

    摘要翻译: 本发明提供用于生物样品的自动处理的装置,装置和方法。 本发明提供了在多于一个洗涤盆中用处理流体顺序处理生物样品的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和蛋白质印迹法的自动化方法。 在一些实施方案中,本发明提供了Southern印迹处理的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和Northern印迹法的自动化方法。 在一些实施方案中,本发明提供了在固体支持物上染色生物分子的自动化装置和自动化方法。 在一些实施方案中,本发明提供自动化装置和核酸分离和分离的自动化方法。

    Apparatus for processing biological samples and method thereof
    6.
    发明授权
    Apparatus for processing biological samples and method thereof 有权
    用于处理生物样品的装置及其方法

    公开(公告)号:US09121795B2

    公开(公告)日:2015-09-01

    申请号:US13879995

    申请日:2010-10-29

    摘要: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

    摘要翻译: 本发明提供用于生物样品的自动处理的装置,装置和方法。 本发明提供了在多于一个洗涤盆中用处理流体顺序处理生物样品的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和蛋白质印迹法的自动化方法。 在一些实施方案中,本发明提供了Southern印迹处理的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和Northern印迹法的自动化方法。 在一些实施方案中,本发明提供了在固体支持物上染色生物分子的自动化装置和自动化方法。 在一些实施方案中,本发明提供自动化装置和核酸分离和分离的自动化方法。