Patent search ap:"Marc STADLER" Page 1

1.

发明申请
LONG CHAIN GLYCOLIPIDS USEFUL TO AVOID PERISHING OR MICROBIAL CONTAMINATION OF MATERIALS 审中-公开
Title translation: 长链甘露糖苷有助于避免物质的微生物污染或微生物污染

公开(公告)号：US20140178444A1

公开(公告)日：2014-06-26

申请号：US14124429

申请日：2012-06-06

Applicant: Marc Stadler , Jens Bitzer , Bärbel Köpcke , Kathrin Reinhardt , Jana Moldenhauer

Inventor： Marc Stadler , Jens Bitzer , Bärbel Köpcke , Kathrin Reinhardt , Jana Moldenhauer

IPC: A01N43/16 , A61Q5/02 , A23L2/44 , C07H15/04 , A61K8/33

CPC classification number: A01N43/16 , A01N63/04 , A23B4/20 , A23B5/14 , A23B7/154 , A23B9/26 , A23L2/44 , A61K8/33 , A61K8/365 , A61K8/37 , A61K8/99 , A61Q5/02 , A61Q17/005 , C07H15/04 , C12P19/44

Abstract: The invention relates to the use of, and methods of use employing, certain glycolipid compounds as defined in detail below and having preservative or antimicrobial properties, novel compounds of the glycolipid class, and related invention embodiments.The compounds have the formula I wherein m is 3 to 5, n is 2 to 5, o is 0 or 1 and p is 3 to 17, with the proviso that the sum m+n+o+p is not less than 14; and R is a carbohydrate moiety bound via one of its carbon atoms to the binding oxygen, and/or a physiologically, especially pharmaceutically or nutraceutically or cosmetically, acceptable salt thereof, or an ester thereof, as such or in the form of a composition, where the compound may be present in open chain form and/or in the form of a lactone (FIG. 1).

Abstract translation: 本发明涉及使用以下详细定义的具有防腐或抗微生物性质的某些糖脂化合物的使用和使用方法，糖脂类的新型化合物和相关的发明实施方案。化合物具有式I，其中m为3至5，n为2至5，o为0或1，p为3至17，条件是和m + n + o + p不小于14; 并且R是通过其碳原子之一与结合氧结合的碳水化合物部分，和/或其生理学上，特别是其药学上或药学上可接受的盐或其酯，或者以组合物的形式，其中化合物可以以开链形式和/或以内酯的形式存在（图1）。

2.

发明申请
Terpenoid Spiro Ketal Compounds with LXR Agonists Activity, Their Use and Formulations with Them 有权
Title translation: 萜类螺旋酮化合物与LXR激动剂的活性，它们的用途和配方

公开(公告)号：US20130338219A1

公开(公告)日：2013-12-19

申请号：US13994447

申请日：2011-12-08

Applicant: Torsten Grothe , Marc Stadler , Bärbel Köpcke , Ernst Roemer , Jens Bitzer , Philipp Wabnitz , Thomas Küper

Inventor： Torsten Grothe , Marc Stadler , Bärbel Köpcke , Ernst Roemer , Jens Bitzer , Philipp Wabnitz , Thomas Küper

IPC: C07D471/10

CPC classification number: C07D471/10 , A61K31/56 , A61K31/58 , A61K36/07

Abstract: The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable from Agaricus species. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g. cosmetic, purposes.

Abstract translation: 本发明涉及用于单独使用提取物和/或一种或多种天然螺三萜类化合物及其衍生物或作为补充剂的组合物和方法（关于动物和人）。使用的某些材料来自于可从姬松茸（Agaricus）物种获得的烟草系列。治疗包括对对肝X受体的调节作出响应的疾病，病症或病状的预防和/或治疗性治疗，以及相应的治疗方法，制备用于所述治疗的药物和营养制剂。本发明还涉及提取物和化合物在治疗或制备用于预防和/或治疗性治疗的药物（例如营养药物）以及其制备中的用途。它还涉及可用于预防和治疗性治疗的本文所述的药物或营养制剂。它们也可以用于非治疗性的，例如，化妆品，用途。

3.

发明授权
Terpenoid spiro ketal compounds with LXR agonists activity, their use and formulations with them 有权
Title translation: 具有LXR激动剂活性的萜类螺旋酮缩酮化合物，它们的用途和配方

公开(公告)号：US09453016B2

公开(公告)日：2016-09-27

申请号：US13994447

申请日：2011-12-08

Applicant: Torsten Grothe , Marc Stadler , Bärbel Köpcke , Ernst Roemer , Jens Bitzer , Philipp Wabnitz , Thomas Küper

Inventor： Torsten Grothe , Marc Stadler , Bärbel Köpcke , Ernst Roemer , Jens Bitzer , Philipp Wabnitz , Thomas Küper

IPC: A61K31/35 , C07D493/00 , C07D471/10 , A61K31/56 , A61K31/58 , A61K36/07

CPC classification number: C07D471/10 , A61K31/56 , A61K31/58 , A61K36/07

Abstract: The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable from Agaricus species. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g. cosmetic, purposes.

Abstract translation: 本发明涉及用于单独使用提取物和/或一种或多种天然螺三萜类化合物及其衍生物或作为补充剂的组合物和方法（关于动物和人）。使用的某些材料来自于可从姬松茸（Agaricus）物种获得的烟草系列。治疗包括对对肝X受体的调节作出响应的疾病，病症或病状的预防和/或治疗性治疗，以及相应的治疗方法，制备用于所述治疗的药物和营养制剂。本发明还涉及提取物和化合物在治疗或制备用于预防和/或治疗性治疗的药物（例如营养药物）以及其制备中的用途。它还涉及可用于预防和治疗性治疗的本文所述的药物或营养制剂。它们也可以用于非治疗性的，例如，化妆品，用途。