Phage-resistant streptococcus
    2.
    发明授权
    Phage-resistant streptococcus 失效
    抗噬菌体链球菌

    公开(公告)号:US5766904A

    公开(公告)日:1998-06-16

    申请号:US665119

    申请日:1996-06-14

    摘要: DNA fragment of phages which are virulent towards a Streptococcus, capable of conferring on a Streptococcus containing it resistance to at least one phage, especially a fragment homologous or hybridizing to the 3.6 kb HindIII fragment present in the plasmid CNCM I-1588 or the 6.5 kb EcoRV fragment present in the plasmid CNCM I-1589. Process for making a Streptococcus resistant to at least one phage, by cloning into a vector a DNA fragment of a phage which is virulent towards a Streptococcus, capable of conferring on a Streptococcus resistance to at least one phage and introducing the vector into a Streptococcus.

    摘要翻译: 对链球菌毒性的噬菌体的DNA片段能够赋予含有至少一个噬菌体的链球菌,特别是与存在于质粒CNCM I-1588中的3.6kb HindIII片段同源或杂交的片段或6.5kb EcoRV片段存在于质粒CNCM I-1589中。 通过向载体克隆对链球菌有毒的噬菌体的DNA片段,能够赋予至少一个噬菌体的抗链球菌抗性并将载体引入链球菌中,以制备对至少一个噬菌体有抗性的链球菌的方法。