公开(公告)号：US20070177944A1

公开(公告)日：2007-08-02

申请号：US11668395

申请日：2007-01-29

申请人： Stuart Smith ,  Mark Olson

发明人： Stuart Smith ,  Mark Olson

IPC分类号： F16L1/12

CPC分类号： F16L1/202 ,  F16L1/207 ,  F16L1/235

摘要： Disclosed are a method and apparatus for laying down, abandoning and/or recovering a pipe on the sea floor. During lay-down and abandonment, the pipe is lowered by a high capacity winch to an intermediate depth, at which the loading exerted by the pipe has dropped to within the rated capacity of a low capacity winch, to which the loading is then transferred. The high capacity winch line is then recovered to the attendant vessel and the pipe lowered to the sea floor using the low capacity winch. Pipe recovery is essentially a reversal of the above procedure. In this way, the length of the line of the high capacity winch is considerably reduced, which reduces the winch size and hence cost.

摘要翻译： 公开了用于在海底放置，放弃和/或回收管道的方法和装置。 在放置和放弃期间，管道被高容量绞盘降低到中间深度，在该中间深度处，由管道施加的负载已经下降到低容量绞车的额定容量内，然后将负载转移到其中。 然后将高容量绞车线恢复到服务员，并使用低容量绞车将管降低到海底。 管道恢复基本上是上述过程的逆转。 以这种方式，大容量绞盘的长度大大降低，这降低了绞车的尺寸并因此降低了成本。

公开(公告)号：US20050211254A1

公开(公告)日：2005-09-29

申请号：US10806625

申请日：2004-03-23

申请人： Mark Olson

发明人： Mark Olson

IPC分类号： A61F11/00 ,  A61F11/08

CPC分类号： A61F11/08

摘要： The invention includes an ear or nose plug and a method of forming such an ear or nose plugs. The method may include providing silicone rubber base and catalyst materials and mixing about equal parts of the silicone rubber base and catalyst materials to form a homogeneous putty. The method may further include forming a bullet shaped and sized module of the homogeneous putty. The method may further include inserting the module within an ear or nose cavity using enough gentle pressure to allow the module to conform to the ear or nose cavity and leaving enough of the module outside of the cavity to grasp for removal. The method may further include waiting a predetermined amount of time to cure and removing a custom shaped ear or nose plug. Embodiments of an ear or nose plug formed by the above method are also disclosed. The ear or nose plugs are formed in situ and quickly cure according to the methods of the present invention.

摘要翻译： 本发明包括耳塞或鼻塞以及形成这种耳塞或鼻塞的方法。 该方法可以包括提供硅橡胶基质和催化剂材料，并且将约等份的硅橡胶基质和催化剂材料混合以形成均匀的油灰。 该方法还可以包括形成均匀油灰的子弹形状和尺寸的模块。 该方法可以进一步包括使用足够温和的压力将模块插入耳朵或鼻腔内，以允许模块符合耳朵或鼻腔，并且将足够的模块留在空腔外部以抓住去除。 该方法还可以包括等待预定量的时间来固化和移除定制的形状的耳塞或鼻塞。 还公开了通过上述方法形成的耳塞或鼻塞的实施例。 根据本发明的方法，耳塞或鼻塞原地形成并快速固化。

公开(公告)号：US20100098291A1

公开(公告)日：2010-04-22

申请号：US12252758

申请日：2008-10-16

申请人： Peter J. Dugan ,  Mark Olson ,  Stephen R. Shafer ,  Rosemary D. Paradis

发明人： Peter J. Dugan ,  Mark Olson ,  Stephen R. Shafer ,  Rosemary D. Paradis

IPC分类号： G06K9/00

CPC分类号： G06K9/4647

摘要： Method and system for identifying object type. In one embodiment, the method and systems of these teachings utilize a group of object measures and a decision algorithm in order to identify object type.

摘要翻译： 识别对象类型的方法和系统。 在一个实施例中，这些教导的方法和系统利用一组对象度量和决策算法来识别对象类型。

公开(公告)号：US07137200B2

公开(公告)日：2006-11-21

申请号：US10914606

申请日：2004-08-09

申请人： Fred Shepherd ,  Martin Kobiela ,  Mark Olson

发明人： Fred Shepherd ,  Martin Kobiela ,  Mark Olson

IPC分类号： B63B22/00 ,  B23P11/00 ,  B23P17/00

CPC分类号： B63B22/00 ,  B63B22/02 ,  B63B22/026 ,  Y10T29/49616 ,  Y10T29/49826 ,  Y10T29/49904

摘要： Buoys are used for mooring purposes and as navigational marks. An embodiment of the invention is be explained in relation to catenary anchor leg mooring (CALM) buoys.Conventional CALM buoys generally have a hull constructed of steel plate by traditional ship building techniques requiring plate benders. Webs, beams and girders are welded inside the hull which is divided into several tanks. The buoy has a central moonpool and a steel turntable. Bending plate, in effect, doubles its cost.A method of constructing a buoy is disclosed, comprising: constructing a framework and affixing flat steel plate to it.

摘要翻译： 浮标用于系泊目的和导航标记。 关于悬链锚腿系泊（CALM）浮标来说明本发明的一个实施例。 常规的CALM浮标通常具有由钢板构成的船体，其通过传统的造船技术需要弯板机。 网，梁和桁架焊接在船体内，分为几个坦克。 浮标有一个中央月球和钢铁转盘。 弯曲板实际上是其成本的两倍。 公开了一种构造浮标的方法，包括：构造框架并将平板钢板固定到其上。

公开(公告)号：US20050252663A1

公开(公告)日：2005-11-17

申请号：US10847489

申请日：2004-05-17

申请人： Mark Olson ,  Richard Hilderbrandt

发明人： Mark Olson ,  Richard Hilderbrandt

IPC分类号： A24F25/00 ,  A61L9/04 ,  A62C35/00 ,  A62C37/36 ,  G01J1/04 ,  G08B17/02 ,  G08B17/103

CPC分类号： G08B17/02 ,  A62C37/36 ,  G08B17/103

摘要： An Electro-mechanical device utilizing a fiber optic based sensor (Fiber Optic strand) for the purpose of detecting and extinguishing a fire momentarily after ignition. A light signal transmitted through the sensor (Fiber Optic strand) is used as a means to urge a spring loaded valve (Firing Valve) against its established position, thus blocking the dispersal of fire suppressing agents. This condition will persist until the sensor (Fiber Optic strand) is damaged by the presence of open flame in close proximity.

摘要翻译： 一种利用基于光纤的传感器（Fiber Optic strand）的机电装置，用于在点火之后立即检测和熄灭火灾。 通过传感器（Fiber Optic strand）传输的光信号被用作将弹簧加载的阀（燃烧阀）推到其建立位置的手段，从而阻止消火剂的分散。 这种情况将持续到传感器（Fiber Optic strand）由于近距离存在明火而损坏。

公开(公告)号：US20050156413A1

公开(公告)日：2005-07-21

申请号：US10761449

申请日：2004-01-20

申请人： Mark Olson

发明人： Mark Olson

IPC分类号： B60R21/231 ,  B60R21/232 ,  B60R21/233 ,  B60R21/22

CPC分类号： B60R21/232 ,  B60R2021/23316

摘要： An air bag assembly (20) including air bag (30) having at least a first inflatable region (32) having a plurality of restrictions peripherally located about the inflatable region and configured to restrict the degree of inflation of the air bag proximate the restrictions and configured to permit the first inflatable region of the air bag to achieve its maximum inflation in a region interior to the plurality of restrictions.

摘要翻译： 一种气囊组件（20），其包括具有至少第一可充气区域（32）的气囊（30），所述第一可膨胀区域（32）具有围绕所述可充气区域周边地设置的多个限制，并且被配置为限制所述气囊在所述限制附近的充气程度， 被配置为允许所述气囊的第一可充气区域在所述多个限制内部的区域中实现其最大充气。

公开(公告)号：US20050064526A1

公开(公告)日：2005-03-24

申请号：US10767687

申请日：2004-01-29

申请人： Robert Ulrich ,  Mark Olson ,  Sina Bavari

发明人： Robert Ulrich ,  Mark Olson ,  Sina Bavari

IPC分类号： C07K14/31 ,  C12N1/21 ,  G01N33/554 ,  C07H21/04 ,  C12N15/74 ,  G01N33/569

CPC分类号： C07K14/31

摘要： The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.

摘要翻译： 本发明涉及遗传减毒的超抗原毒素疫苗改变，使得超抗原属性不存在，然而有效识别超抗原并产生适当的免疫应答。 显示减毒的超抗原毒素保护动物免受野生型毒素的攻击。 描述了生产和使用改变的超抗原毒素的方法。

公开(公告)号：US06358718B1

公开(公告)日：2002-03-19

申请号：US09538871

申请日：2000-03-30

申请人： Mark Olson ,  Atilla Szebeni

发明人： Mark Olson ,  Atilla Szebeni

IPC分类号： C12N996

CPC分类号： C12N9/96

摘要： The present invention provides methods for stabilizing proteins, preventing protein aggregation, renaturation of previously-denatured proteins, reactivating a protein that has been inactivated by denaturation, preserving enzyme activities under conditions of elevated temperatures, inducing thermotolerance in bacteria, increasing the temperature optimum for the activity of an enzyme, and preventing formation of inclusion bodies by bacterially-expressed recombinant proteins.

摘要翻译： 本发明提供了稳定蛋白质的方法，防止蛋白质聚集，先前变性蛋白质的复性，使已变性失活的蛋白质再活化，在升高的温度条件下保存酶活性，诱导细菌耐热性，增加最佳的温度 酶的活性，并且通过细菌表达的重组蛋白阻止包涵体的形成。

公开(公告)号：US2029440A

公开(公告)日：1936-02-04

申请号：US2878335

申请日：1935-06-27

申请人： MARK OLSON

发明人： MARK OLSON

IPC分类号： G05D23/275

CPC分类号： G05D23/2754

公开(公告)号：US20060009619A1

公开(公告)日：2006-01-12

申请号：US10923022

申请日：2004-08-23

申请人： Mark Olson ,  Charles Millard ,  Michael Byrne ,  Robert Wannemacher ,  Ross LeClaire

发明人： Mark Olson ,  Charles Millard ,  Michael Byrne ,  Robert Wannemacher ,  Ross LeClaire

IPC分类号： C07K14/415 ,  A61K36/47

CPC分类号： C07K14/415 ,  A61K39/00 ,  A61K2039/505 ,  C07K16/16

摘要： Disclosed herein are polypeptides and variants thereof comprising a polypeptide sequence having substantial identity to ricin A chain (RTA) that lack detectable N-glycosidase-rRNA activity or exhibit reduced N-glycosidase-rRNA activity as compared to controls and methods of making and using thereof. The polypeptides and variants have a greater solubility in aqueous solutions of physiological pH and ionic strength than RTA and also retain the integrity of the neutralizing immunological epitope of wild type RTA. Also disclosed are immunogenic compositions that may be used to immunize a subject against ricin intoxication. Methods of immunizing against, treating, and preventing ricin intoxication are disclosed.