Isolation of phosphoproteins, glycoproteins and fragments thereof
    2.
    发明授权
    Isolation of phosphoproteins, glycoproteins and fragments thereof 有权
    磷酸蛋白,糖蛋白及其片段的分离

    公开(公告)号:US08835612B2

    公开(公告)日:2014-09-16

    申请号:US13270148

    申请日:2011-10-10

    CPC classification number: C07K1/32

    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.

    Abstract translation: 本发明提供了选择性分离磷酸化和糖基化蛋白质及其片段的方法和装置。 金属阳离子用于沉淀含有磷酸基团和/或糖基团的蛋白质或蛋白质片段。 样品制备方法可用于几种类型的生物样品,包括HeLa细胞,食物和人脑脊液。 蛋白质被分离,回收并准备好通过质谱法或其他分析方法进行分析,允许检测限降低到飞甲的水平。 该方法和装置是蛋白质分析和诊断领域的宝贵工具。

    Isolation of Phosphoproteins, Glycoproteins and Fragments thereof
    3.
    发明申请
    Isolation of Phosphoproteins, Glycoproteins and Fragments thereof 有权
    磷蛋白,糖蛋白及其片段的分离

    公开(公告)号:US20120088906A1

    公开(公告)日:2012-04-12

    申请号:US13270148

    申请日:2011-10-10

    CPC classification number: C07K1/32

    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.

    Abstract translation: 本发明提供了选择性分离磷酸化和糖基化蛋白质及其片段的方法和装置。 金属阳离子用于沉淀含有磷酸基团和/或糖基团的蛋白质或蛋白质片段。 样品制备方法可用于几种类型的生物样品,包括HeLa细胞,食物和人脑脊液。 蛋白质被分离,回收并准备好通过质谱法或其他分析方法进行分析,允许检测限降低到飞甲的水平。 该方法和装置是蛋白质分析和诊断领域的宝贵工具。

    ROOF FRAME FOR A MOTOR VEHICLE
    5.
    发明申请
    ROOF FRAME FOR A MOTOR VEHICLE 有权
    电动车辆的车顶框架

    公开(公告)号:US20080073943A1

    公开(公告)日:2008-03-27

    申请号:US11862286

    申请日:2007-09-27

    Abstract: A frame for a vehicle sliding sunroof or tilt-slide sunroof is proposed, comprising at least one single-piece frame base element (22), that is embodied as a plastic injection-molded piece and comprises at least one front frame piece (24) and two side stringers (26, 28) that are directed in the vehicle's longitudinal direction. For formation of a light and stiff frame, the frame base element (22) according to the invention is embodied as a composite component, and provided with at least one profile- or cup-shaped inserted piece (38, 40) that serves as a reinforcing element.

    Abstract translation: 提出了一种用于车辆滑动天窗或倾斜滑动天窗的框架,其包括至少一个单件框架基座元件(22),其被实施为塑料注射成型件,并且包括至少一个前框架件(24) 和两个侧向纵梁(26,28),其被引导在车辆的纵向方向上。 为了形成轻型和刚性的框架,根据本发明的框架基座元件(22)被实施为复合构件,并且设置有至少一个型材或杯形插入件(38,40),其用作 增强元件。

    Roof frame for a motor vehicle
    6.
    发明授权
    Roof frame for a motor vehicle 有权
    汽车车顶架

    公开(公告)号:US07625040B2

    公开(公告)日:2009-12-01

    申请号:US11862286

    申请日:2007-09-27

    Abstract: A frame for a vehicle sliding sunroof or tilt-slide sunroof is proposed, comprising at least one single-piece frame base element (22), that is embodied as a plastic injection-molded piece and comprises at least one front frame piece (24) and two side stringers (26, 28) that are directed in the vehicle's longitudinal direction. For formation of a light and stiff frame, the frame base element (22) according to the invention is embodied as a composite component, and provided with at least one profile- or cup-shaped inserted piece (38, 40) that serves as a reinforcing element.

    Abstract translation: 提出了一种用于车辆滑动天窗或倾斜滑动天窗的框架,其包括至少一个单件框架基座元件(22),其被实施为塑料注射成型件,并且包括至少一个前框架件(24) 以及两个侧向纵梁(26,28),其被引导在车辆的纵向方向上。 为了形成轻型和刚性的框架,根据本发明的框架基座元件(22)被实施为复合构件,并且设置有至少一个型材或杯形插入件(38,40),其用作 增强元件。

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