-
公开(公告)号：US20230285937A1
公开(公告)日：2023-09-14
申请号：US18197804
申请日：2023-05-16
Applicant: Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
Inventor： Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
IPC: B01J20/30 , G01N30/38 , B01J20/282 , B01J20/283 , B01J20/284 , B01J20/285
CPC classification number: B01J20/3092 , G01N30/38 , B01J20/282 , B01J20/283 , B01J20/284 , B01J20/285 , G01N2030/045
Abstract: This invention employs solid phase extraction media and column methods to apply external and internal standards and compounds. Analytical standard or compounds including PFAS are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with an elution solvent or reagent.
-
公开(公告)号：US11656209B2
公开(公告)日：2023-05-23
申请号：US16662641
申请日：2019-10-24
Applicant: Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
Inventor： Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
IPC: G01N30/38 , G01N30/04 , B01J20/282 , B01J20/281
CPC classification number: G01N30/482 , B01J20/282 , G01N30/38 , G01N2030/045 , G01N2030/382
Abstract: This invention employs columns and methods to apply external and internal standards and compounds. Analytical standard or compounds are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with a solvent.
-
3.发明授权Hydrolysates made of plant extracts and antibacterial agent containing the same 有权由植物提取物制成的水解物和含有它的抗菌剂公开(公告)号：US08734857B2
公开(公告)日：2014-05-27
申请号：US12740396
申请日：2008-10-30
Applicant: Guenther Bonn , Guenther Stecher , Michael A. Popp , Robert Mayer
Inventor： Guenther Bonn , Guenther Stecher , Michael A. Popp , Robert Mayer
IPC: A61K36/00
CPC classification number: A61K36/85 , A61K8/97 , A61K36/185 , A61K36/35 , A61K36/51 , A61K36/515 , A61K36/70 , A61Q11/00 , A61Q19/00 , Y02A50/473
Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
Abstract translation: 本发明涉及由至少一种提取物制成的抗菌剂和水解产物，所述提取物通过使用来自干燥植物材料的乙醇/水提取而制备，所述提取物为：a）至少一种选自以下的植物：马鞭草 L.，Sambucus nigra L.，Primula veris L.，Primula elatior（L.）Hill和Gentiana lutea L. 和它们的混合物; 或b）混合物：马鞭草（L.），接骨木（Sambucus nigra L.），樱草属（Primula veris L.），龙胆（Gentiana lutea L.）和罗米and（Rumicis herba） 随后除去乙醇/水提取剂，其中可以通过使用无机酸的水解处理从提取物中获得水解产物。 根据本发明的水解产物显示出对皮肤，耳朵，鼻子，喉咙和呼吸系统相关细菌的显着的抗菌作用。
-
4.发明申请METHOD FOR COVALENTLY ATTACHING POLYMERIC MONOLITHS TO POLYETHER ETHER KETONE (PEEK) SURFACES 审中-公开将聚合物单体与聚醚醚酮（PEEK）表面共价连接的方法公开(公告)号：US20120255894A1
公开(公告)日：2012-10-11
申请号：US13516810
申请日：2010-12-20
Applicant: Guenther Bonn , Samuel Clark Ligon
Inventor： Guenther Bonn , Samuel Clark Ligon
CPC classification number: B01J20/285 , B01D15/206 , B01D15/22 , B01J20/261 , B01J20/30 , B01J20/3092 , B01J2220/82 , B01J2220/86 , G01N30/6052 , G01N30/6078 , G01N2030/528 , G01N2030/567
Abstract: Method for covalently attaching polymeric monoliths to polyether ether ketone (PEEK) surfaces The present invention provides a method of covalently attaching a polymeric monolith to the internal surface of polyether ether ketone (PEEK) tubing and column housings, comprising the steps of: (a) reducing the ketone group of the PEEK to a hydroxyl group to obtain a modified PEEK, (b) optionally reacting the hydroxyl group obtained in step (a) with a compound having an active vinyl group to form a modified PEEK selected from the group of acrylate modified PEEK, methacrylate modified PEEK, styrene modified PEEK and epoxy modified PEEK, and (c) reacting the modified PEEK obtained in step (a) or (b) with a polymer or polymerization mixture for forming the polymeric monolith. Hereby, the mechanical stability and solvent durability of larger diameter monolithic columns as well as their overall performance are improved.
Abstract translation: 将聚合物整料共价连接到聚醚醚酮（PEEK）表面上的方法本发明提供了一种将聚合物整料共价连接到聚醚醚酮（PEEK）管和柱壳体的内表面上的方法，包括以下步骤：（a） 将PEEK的酮基还原为羟基以获得改性的PEEK，（b）任选地使步骤（a）中获得的羟基与具有活性乙烯基的化合物反应以形成选自丙烯酸酯的改性PEEK 改性PEEK，甲基丙烯酸酯改性PEEK，苯乙烯改性PEEK和环氧改性PEEK，和（c）使步骤（a）或（b）中获得的改性PEEK与形成聚合物整料的聚合物或聚合混合物反应。 因此，改善了较大直径单块柱的机械稳定性和溶剂耐久性以及其整体性能。
-
公开(公告)号：US09120847B2
公开(公告)日：2015-09-01
申请号：US13744305
申请日：2013-01-17
Applicant: Matthias Rainer , Douglas T. Gjerde , Guenther Bonn
Inventor： Matthias Rainer , Douglas T. Gjerde , Guenther Bonn
CPC classification number: C07K1/303
Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
Abstract translation: 本发明提供了选择性分离磷酸化和糖基化蛋白质及其片段的方法和装置。 镧系金属阳离子用于沉淀含有磷酸基团和/或糖基团的蛋白质或蛋白质片段。 样品制备方法可用于许多类型的生物样品，包括HeLa细胞，食物和人脑脊液。 蛋白质被分离，回收并准备好通过质谱法或其他分析方法进行分析，允许检测限降低到飞甲的水平。 该方法和装置是蛋白质分析和诊断领域的宝贵工具。
-
Patent Agency Ranking
公开(公告)号：US20140251918A1
公开(公告)日：2014-09-11
申请号：US14203365
申请日：2014-03-10
Applicant: Matthias Rainer , Lee Hoang , Douglas T. Gjerde , Guenther Bonn
Inventor： Matthias Rainer , Lee Hoang , Douglas T. Gjerde , Guenther Bonn
IPC: G01N1/34
CPC classification number: G01N1/34 , B01L3/0275 , B01L2200/16 , B01L2300/0681 , G01N33/6842 , G01N2001/4061
Abstract: An automated or semi-automated method was developed for the isolation of proteins using lanthanide metals. Phosphoproteins and glycoproteins can be isolated from complex biological samples using filtration with novel column configurations.
Abstract translation: 开发了使用镧系金属分离蛋白质的自动或半自动化方法。 磷酸化蛋白和糖蛋白可以从复杂的生物样品中分离，使用新颖的柱构型进行过滤。
-
公开(公告)号：US20100009845A1
公开(公告)日：2010-01-14
申请号：US12479676
申请日：2009-06-05
Applicant: Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
Inventor： Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
IPC: B01J20/26
CPC classification number: B01J20/28042 , B01J20/02 , B01J20/0211 , B01J20/0237 , B01J20/0281 , B01J20/043 , B01J20/048 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/20 , B01J20/205 , B01J20/26 , B01J20/28007 , B01J20/28026 , B01J2220/64 , B82Y30/00 , G01N2035/1053
Abstract: The present invention relates to a pipette tip which is fitted with a porous organic monolith which is doped with active particles. Due to a unique polymerization method, the extraction tips stay highly permeable which allows sample to pass through the monolithic bed. The extraction tip represents an ideal tool for solid phase extraction, especially for desalting, isolating and purifying biomolecules such as peptides and proteins.
Abstract translation: 吸液头技术领域本发明涉及一种移液管吸头，其配有掺有活性颗粒的多孔有机整料。 由于独特的聚合方法，萃取尖端保持高渗透性，允许样品通过整体床。 提取尖端代表固相萃取的理想工具，特别是用于脱盐，分离和纯化生物分子如肽和蛋白质。
-
公开(公告)号：US12269012B2
公开(公告)日：2025-04-08
申请号：US18197804
申请日：2023-05-16
Applicant: Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
Inventor： Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
IPC: B01J20/30 , B01J20/282 , B01J20/283 , B01J20/284 , B01J20/285 , G01N30/04 , G01N30/38
Abstract: This invention employs solid phase extraction media and column methods to apply external and internal standards and compounds. Analytical standard or compounds including PFAS are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with an elution solvent or reagent.
-
公开(公告)号：US20210072201A1
公开(公告)日：2021-03-11
申请号：US16662641
申请日：2019-10-24
Applicant: Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
Inventor： Thomas Jakschitz , Douglas T. Gjerde , Guenther Bonn
IPC: B01J20/281 , G01N30/38
Abstract: This invention employs columns and methods to apply external and internal standards and compounds. Analytical standard or compounds are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with a solvent.
-
10.发明申请HYDROLYSATES MADE OF PLANT EXTRACTS AND ANTIBACTERIAL AGENT CONTAINING THE SAME 有权植物提取物和含有其的抗菌剂的水解产物公开(公告)号：US20100323013A1
公开(公告)日：2010-12-23
申请号：US12740396
申请日：2008-10-30
Applicant: Guenther Bonn , Guenther Stecher , Michael A. Popp , Robert Mayer
Inventor： Guenther Bonn , Guenther Stecher , Michael A. Popp , Robert Mayer
CPC classification number: A61K36/85 , A61K8/97 , A61K36/185 , A61K36/35 , A61K36/51 , A61K36/515 , A61K36/70 , A61Q11/00 , A61Q19/00 , Y02A50/473
Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
Abstract translation: 本发明涉及由至少一种提取物制成的抗菌剂和水解产物，所述提取物通过使用来自干燥植物材料的乙醇/水提取而制备，所述提取物为：a）至少一种选自以下的植物：马鞭草 L.，Sambucus nigra L.，Primula veris L.，Primula elatior（L.）Hill和Gentiana lutea L. 和它们的混合物; 或b）混合物：马鞭草（L.），接骨木（Sambucus nigra L.），樱草属（Primula veris L.），龙胆（Gentiana lutea L.）和罗米and（Rumicis herba） 随后除去乙醇/水提取剂，其中可以通过使用无机酸的水解处理从提取物中获得水解产物。 根据本发明的水解产物显示出对皮肤，耳朵，鼻子，喉咙和呼吸系统相关细菌的显着的抗菌作用。
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.011 seconds)
