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    Method and apparatus for delivering a drug
    2.
    发明申请
    Method and apparatus for delivering a drug 审中-公开
    用于递送药物的方法和装置

    公开(公告)号：US20080086108A1

    公开(公告)日：2008-04-10

    申请号：US11973007

    申请日：2007-10-04

    Applicant: Michael I. Falkel ,  Matthew J. Stepovich

    Inventor： Michael I. Falkel ,  Matthew J. Stepovich

    IPC: A61M5/31

    CPC classification number: A61C19/08 ,  A61C5/62 ,  A61M5/3257

    Abstract: A device to facilitate the administration of an injection to a patient can comprise a hand piece that comprises of a core and a sheath. The core can comprise of a needle assembly and a thumb piece, and the sheath can enclose a portion of the core, at least in some configurations. In some embodiments, the hand piece can comprise of at least one releasable locking mechanism to enable the sheath to lock onto the core in different positions, particularly a safe position in which the needle assembly is enclosed within the sheath and an exposed position in which the needle is exposed from the sheath. A fluid connection within the core connects the needle assembly with a fluid source outside the core. The user can grip the hand piece by supporting their thumb on the thumb piece and positioning the hand piece between the user's two non-thumb fingers. Thus, the user can employ a traditional one-hand grip corresponding to the use of a manual dental syringe. To unlock the sheath of the hand piece, one of the user's non-thumb fingers can be positioned near the locking mechanism to provide ready release of the locking mechanism such that movement of the sheath relative to the needle assembly can occur to expose the needle for an injection into the patient. After delivery of a drug, the sheath can be moved to enclose the needle for later use or disposal.

    Abstract translation: 便于对患者进行注射的装置可以包括由芯和护套组成的手部件。 芯可以包括针组件和拇指片，并且护套可以至少在一些构造中包围芯的一部分。 在一些实施例中，手持件可以包括至少一个可释放的锁定机构，以使护套能够在不同的位置，特别是其中针组件被封装在护套内的安全位置和暴露位置 针从皮肤暴露出来。 芯内的流体连接将针组件与芯之外的流体源连接。 用户可以通过将拇指支撑在拇指片上并将手部定位在使用者的两拇指之间来抓住手部。 因此，用户可以采用与使用手动牙科针筒相对应的传统单手把手。 为了解除手部件的护套，用户的非拇指指状物中的一个可以定位在锁定机构附近，以提供锁定机构的准备释放，使得可以发生护套相对于针组件的移动，以使针头暴露于针 注入患者。 药物递送后，护套可以移动以包围针头供以后使用或处置。

    HERBAL COMPOSITIONS INCLUDING CANNABIDIOL TO ENHANCE THE SEXUAL EXPERIENCE
    3.
    发明申请
    HERBAL COMPOSITIONS INCLUDING CANNABIDIOL TO ENHANCE THE SEXUAL EXPERIENCE 审中-公开

    公开(公告)号：US20170246120A9

    公开(公告)日：2017-08-31

    申请号：US14886101

    申请日：2015-10-19

    Applicant: Matthew J. Stepovich

    Inventor： Matthew J. Stepovich

    IPC: A61K31/05

    CPC classification number: A61K31/05 ,  A61K9/0014 ,  A61K9/107

    Abstract: The present invention provides herbal compositions comprising cannabidiol (CBD) for enhancing the sexual experience. In accordance with the invention, a physiologically acceptable composition including an emulsion of cannabidiol and a carrier substance is delivered to the skin, one or membranes or other surfaces of the human body where absorption of the herbal composition can occur. In some embodiments of the invention the delivery mechanism includes an apparatus, including but not limited to dissolving strips, vaporizers, pump sprays, single-use foil tubes, and condoms. The delivery occurs prior to or during sexual activity. Some embodiments of the invention provide carrier substances that will improve the effectiveness of the CBD in enhancing the sexual experience, and that may improve the experience in other ways, such as by adding flavors or fragrances.

    METHODS FOR BUFFERING MEDICAL SOLUTIONS
    4.
    发明申请
    METHODS FOR BUFFERING MEDICAL SOLUTIONS 审中-公开
    缓解医疗解决方案的方法

    公开(公告)号：US20110282316A1

    公开(公告)日：2011-11-17

    申请号：US12944492

    申请日：2010-11-11

    Applicant: Matthew J. Stepovich ,  Michael I. Falkel ,  Harry Nguyen

    Inventor： Matthew J. Stepovich ,  Michael I. Falkel ,  Harry Nguyen

    IPC: A61J1/20 ,  A61J1/14

    CPC classification number: A61K31/00 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2089 ,  A61K9/0019 ,  A61K31/137 ,  A61K47/02

    Abstract: A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage. By delivering a buffer with a precisely controlled pH, accurate buffering of the anesthetic can be achieved.

    Abstract translation: 用于将缓冲溶液输送到缓冲筒中的装置包括针组件和推动器。 缓冲药筒和麻醉药筒的隔垫前进到转移针上，推动器将柱塞推进到缓冲药筒中，以通过转移针将缓冲液输送到麻醉药筒中。 单独的排气针允许麻醉药筒的过量麻醉剂被耗尽。 通常设置压缩构件以在消毒和/或存储期间保持抵抗缓冲筒上的柱塞的力以对内容物进行加压和稳定。 通过输送具有精确控制pH的缓冲液，可以实现麻醉剂的精确缓冲。

    METHODS AND SYSTEMS FOR BUFFERING SOLUTIONS WITH CONTROLLED TONICITY
    6.
    发明申请
    METHODS AND SYSTEMS FOR BUFFERING SOLUTIONS WITH CONTROLLED TONICITY 审中-公开
    用于缓冲控制解决方案的方法和系统

    公开(公告)号：US20140224376A1

    公开(公告)日：2014-08-14

    申请号：US13767692

    申请日：2013-02-14

    Applicant: Matthew J. Stepovich ,  Michael I. Falkel ,  Mark Foley

    Inventor： Matthew J. Stepovich ,  Michael I. Falkel ,  Mark Foley

    IPC: A61J1/20 ,  A61J1/14

    CPC classification number: A61J1/062

    Abstract: An anesthetic cartridge is adapted to receive a volume of buffer by displacing a plunger in one end of the anesthetic cartridge inwardly so that addition of the buffer volume will not displace the plunger excessively beyond the end of the cartridge body. The inwardly displaced end is protected by a plug or cover which prevents contamination and which is ejected when the buffer is added. The amount of buffer volume injected is selected to raise the pH of the anesthetic to a target value and to simultaneously achieve a target tonicity.

    Abstract translation: 麻醉药筒适于通过将麻醉药筒的一端中的柱塞向内移位而接收一定体积的缓冲液，使得缓冲体积的增加不会使柱塞过度超过药筒主体的端部。 向内移动的端部由防止污染的塞子或盖子保护，并且当添加缓冲液时被排出。 选择缓冲体积的量来将麻醉剂的pH提高到目标值，同时达到目标张力。

    METHOD AND SYSTEMS FOR BUFFERING ANESTHETIC CARTRIDGES WITH BUFFERING SOLUTIONS
    7.
    发明申请
    METHOD AND SYSTEMS FOR BUFFERING ANESTHETIC CARTRIDGES WITH BUFFERING SOLUTIONS 审中-公开
    用缓冲溶液缓冲麻醉药盒的方法和系统

    公开(公告)号：US20110247722A1

    公开(公告)日：2011-10-13

    申请号：US13082260

    申请日：2011-04-07

    Applicant: Matthew J. Stepovich ,  Michael I. Falkel

    Inventor： Matthew J. Stepovich ,  Michael I. Falkel

    IPC: B65B1/04 ,  B65D85/00

    CPC classification number: A61M5/1782 ,  A61J1/062 ,  A61M5/24 ,  A61M2005/2093 ,  B65B3/003 ,  B65B3/30

    Abstract: An anesthetic cartridge is adapted to receive a volume of buffer by displacing a plunger in one end of the anesthetic cartridge inwardly so that addition of the buffer volume will not displace the plunger excessively beyond the end of the cartridge body. By properly determining the amount of buffer volume required to raise the pH of the anesthetic to a target value, the degree of inward displacement of the plunger can be determined and the cartridge can be used with a system for delivering a precise amount of buffer solution having a known pH into the cartridge to raise its pH, just before the anesthetic is delivered to the patient.

    Abstract translation: 麻醉药筒适于通过将麻醉药筒的一端中的柱塞向内移位而接收一定体积的缓冲液，使得缓冲体积的增加不会使柱塞过度超过药筒主体的端部。 通过适当地确定将麻醉剂的pH提高到目标值所需的缓冲体积的量，可以确定柱塞的向内位移程度，并且可以将该筒与用于输送精确量的缓冲溶液的系统一起使用，该系统具有 在麻醉剂输送到患者之前，将已知的pH调节到药筒中以提高其pH。

    METHODS AND APPARATUS FOR BUFFERING ANESTHETICS
    8.
    发明申请
    METHODS AND APPARATUS FOR BUFFERING ANESTHETICS 有权
    用于缓解麻醉的方法和装置

    公开(公告)号：US20090292271A1

    公开(公告)日：2009-11-26

    申请号：US12406670

    申请日：2009-03-18

    Applicant: Matthew J. Stepovich ,  Michael I. Falkel

    Inventor： Matthew J. Stepovich ,  Michael I. Falkel

    IPC: A61J1/20

    CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2072

    Abstract: A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage.

    Abstract translation: 用于将缓冲溶液输送到缓冲筒中的装置包括针组件和推动器。 缓冲药筒和麻醉药筒的隔垫前进到转移针上，推动器将柱塞推进到缓冲药筒中，以通过转移针将缓冲液输送到麻醉药筒中。 单独的排气针允许麻醉药筒的过量麻醉剂被耗尽。 通常设置压缩构件以在消毒和/或存储期间保持抵抗缓冲筒上的柱塞的力以对内容物进行加压和稳定。

    Methods and apparatus for buffering parenteral solutions
    10.
    发明授权
    Methods and apparatus for buffering parenteral solutions 有权
    用于缓冲肠胃外溶液的方法和装置

    公开(公告)号：US08303566B2

    公开(公告)日：2012-11-06

    申请号：US12833702

    申请日：2010-07-09

    Applicant: Matthew J. Stepovich ,  Michael I. Falkel

    Inventor： Matthew J. Stepovich ,  Michael I. Falkel

    IPC: A61M5/32

    CPC classification number: A61J1/2089 ,  A61J1/1406 ,  A61J1/201 ,  A61J1/2017 ,  A61J1/2072 ,  A61J1/2096 ,  A61M5/1782

    Abstract: A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.

    Abstract translation: 将解决方案从第一盒传送到第二盒中的系统包括盒保持器，柱塞驱动器和盒连接器。 墨盒连接器承载转印针和排气针。 药筒保持器将第一药筒定位在药筒连接器上，使得转移针穿透第一药筒隔膜。 第二盒可移除地插入盒连接器的另一端，使得传送针和排气针都穿过第二盒隔膜。 柱塞驱动器设置成将柱塞推进在第一盒上，以将溶液从第一盒传送到第二盒中，从而将溶液从第二盒通过排气针排出。 盒式连接器包括用于从第二盒接收溶液的密封的内部废物室。

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