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公开(公告)号：US6043073A
公开(公告)日：2000-03-28
申请号：US968752
申请日：1997-08-13
IPC分类号： G01N33/573 , A61K38/22 , A61P37/02 , C07K14/47 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/20 , C12N15/09 , C12N15/55 , C12Q1/44 , C07H21/04 , C12N1/20 , C12N15/00
CPC分类号： C12N9/1205 , C07K14/4722 , C12N9/16 , C12N9/20
摘要： Provided are novel phospholipase D DNA and amino acid sequences. The sequences are useful in methods and compositions for identifying phospholipase D mediator molecules which are in turn useful in therapeutic pharmacuetical compositions for treating rheumatoid arthritis, psoriasis, ulcerative colitis, in wound healing and for treating other diseases or conditions characterized by exhibition of an inflammatory response or in the treatment of cancer and other diseases characterized by pathogenic mitogenicity.
摘要翻译： 提供新的磷脂酶D DNA和氨基酸序列。 该序列在鉴定磷脂酶D介体分子的方法和组合物中是有用的，其又可用于治疗药物组合物，用于治疗类风湿性关节炎，牛皮癣，溃疡性结肠炎，伤口愈合和用于治疗特征为炎症反应特征的其它疾病或病症 或用于治疗特征为致病有丝分裂原的癌症和其他疾病。
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公开(公告)号：US06379665B1
公开(公告)日：2002-04-30
申请号：US09536224
申请日：2000-03-27
IPC分类号： A61K3846
CPC分类号： C12N9/1205 , C07K14/4722 , C12N9/16 , C12N9/20
摘要： Provided are novel phospholipase D DNA and amino acid sequences. The sequences are useful in methods and compositions for identifying phospholipase D mediator molecules which are in turn useful in therapeutic pharmaceutical compositions for treating rheumatoid arthritis, psoriasis, ulcerative colitis, in wound healing and for treating other diseases or conditions characterized by exhibition of an inflammatory response or in the treatment of cancer and other diseases characterized by pathogenic mitogenicity.
摘要翻译： 提供新的磷脂酶D DNA和氨基酸序列。 该序列可用于鉴定磷脂酶D介体分子的方法和组合物，其又可用于治疗类风湿性关节炎，牛皮癣，溃疡性结肠炎，伤口愈合的治疗性药物组合物和用于治疗特征为炎症反应特征的其它疾病或病症 或用于治疗特征为致病有丝分裂原的癌症和其他疾病。
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