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    Cosmetic composition
    1.
    发明授权
    Cosmetic composition 失效
    化妆品组成

    公开(公告)号：US06942878B2

    公开(公告)日：2005-09-13

    申请号：US10363664

    申请日：2001-09-10

    申请人： Nobuaki Ishii ,  Kouichi Wada ,  Junko Futami ,  Michihiro Takama

    发明人： Nobuaki Ishii ,  Kouichi Wada ,  Junko Futami ,  Michihiro Takama

    IPC分类号： A61K8/11 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/35 ,  A61K8/37 ,  A61Q17/04 ,  A61K9/14

    CPC分类号： A61K8/11 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/35 ,  A61K8/37 ,  A61K2800/412 ,  A61K2800/413 ,  A61Q17/04

    摘要： To provide a cosmetic composition having excellent ultraviolet protection against both UVB and UVA, causing neither unpleasant whitening to the applied skin nor skin irritation, and ensuring good feeling on use and high safety and high stability without causing decomposition of the ingredients blended in the cosmetic material, such as organic ultraviolet absorber. A cosmetic composition obtained by using fine particulate titanium oxide and fine particulate zinc oxide each surface-treated with silica, alumina or alumina/silica and having a primary particle size of 0.01 to 0.2 μm in combination and blending titanium oxide and zinc oxide at a mass ratio of 1:4 to 2:3, wherein SPF is maintained as compared with the case where the mass ratio of titanium oxide to zinc oxide is 1:0, and when applied to a thickness of 10 μm, the whiteness W value measured using the CIE color specification system is 20 or less.

    摘要翻译： 为了提供对UVB和UVA均具有优异的紫外线防护性的化妆品组合物，不会对所施用的皮肤造成令人不愉快的美白，也不引起皮肤刺激，并且确保良好的使用感和高安全性和高稳定性，而不会引起混合在化妆品材料中的成分的分解 ，如有机紫外线吸收剂。 通过使用二氧化硅，氧化铝或氧化铝/二氧化硅进行表面处理的细颗粒氧化钛和细粒状氧化锌并且一次粒径为0.01〜0.2μm的组合并以氧化钛和氧化锌的质量混合而获得的化妆品组合物 比例为1:4〜2:3，与氧化钛与氧化锌的质量比为1:0的情况相比，维持SPF，当施加到10μm的厚度时，使用 CIE颜色规格系统为20以下。

    Alkaline lipase, method for producing the same, microorganism producing the same and detergent composition containing alkaline lipase
    2.
    发明授权
    Alkaline lipase, method for producing the same, microorganism producing the same and detergent composition containing alkaline lipase 失效
    碱性脂肪酶，其制造方法，生产该微生物的微生物和含有碱性脂肪酶的洗涤剂组合物

    公开(公告)号：US5454971A

    公开(公告)日：1995-10-03

    申请号：US67075

    申请日：1993-05-26

    申请人： Nobuaki Sakai ,  Masahiro Suzuki ,  Tatsuya Mizukoshi ,  Yukie Goto ,  Keijitsu Tanaka ,  Michihiro Takama ,  Norio Moriya ,  Kazunori Sakimoto

    发明人： Nobuaki Sakai ,  Masahiro Suzuki ,  Tatsuya Mizukoshi ,  Yukie Goto ,  Keijitsu Tanaka ,  Michihiro Takama ,  Norio Moriya ,  Kazunori Sakimoto

    IPC分类号： C11D3/386 ,  C12N9/20 ,  C11D17/00 ,  C12N1/00 ,  D06M16/00

    CPC分类号： C12R1/38 ,  C11D3/38627 ,  C12N9/20 ,  Y10S435/874

    摘要： A microorganism belonging to the genus Pseudomonas; an alkaline lipase produced by the microorganism or its mutants; a method of producing the alkaline lipase; and detergents containing the alkaline lipase as an aid, the alkaline lipase having (1) an operative pH of from 4 to 11.5, and an optimum pH of from 7.0 to 9.5, as measured using triolein emulsion as a substrate; (2) an operative temperature of from 10.degree. to 80.degree. C., and an optimum temperature of from 55.degree. to 65.degree. C., as measured using triolein emulsion as a substrate; (3) a molecular weight of 28,000 .+-.2,000 as measured by electrophoresis using SDS polyacrylamide; (4) isoelectric point of 4.5 .+-.1.5 as measured by isoelectric focusing polyacrylamide gel electrophoresis; and (5) an inhibition of lipase activity by a detergent component of not higher than 50% as measured using sodium linear-alkylbenzenesulfonate as said detergent component.The alkaline lipase has an improved stability against detergent components such as a surfactant and a protease, and can be blended with a detergent together with a protease. The alkaline lipase is less susceptible to inhibition of lipase activity by a detergent component and can increase washing power of detergents.

    摘要翻译： 属于假单胞菌属的微生物; 由微生物或其突变体产生的碱性脂肪酶; 一种生产碱性脂肪酶的方法; 和含有碱性脂肪酶的洗涤剂作为辅助剂，所述碱性脂肪酶具有（1）操作pH为4至11.5，最佳pH为7.0至9.5，使用三油酸酯乳液作为底物; （2）使用三油精乳液作为底物测定的操作温度为10℃至80℃，最适温度为55℃至65℃; （3）通过使用SDS聚丙烯酰胺的电泳测量的分子量为28,000 +/- 2,000; （4）通过等电聚焦聚丙烯酰胺凝胶电泳测量的等电点为4.5 +/- 1.5; 和（5）使用直链烷基苯磺酸钠作为所述洗涤剂组分测定的洗涤剂组分对脂肪酶活性的抑制不高于50％。 碱性脂肪酶对洗涤剂组分如表面活性剂和蛋白酶具有改善的稳定性，并且可与蛋白酶一起与洗涤剂共混。 碱性脂肪酶不太容易被洗涤剂组分抑制脂肪酶活性，并且可以提高洗涤剂的洗涤能力。

    Cosmetic composition
    3.
    发明授权
    Cosmetic composition 有权
    化妆品组成

    公开(公告)号：US06500415B2

    公开(公告)日：2002-12-31

    申请号：US09873398

    申请日：2001-06-05

    申请人： Nobuaki Ishii ,  Junko Futami ,  Kouichi Wada ,  Michihiro Takama

    发明人： Nobuaki Ishii ,  Junko Futami ,  Kouichi Wada ,  Michihiro Takama

    IPC分类号： A61K3174

    CPC分类号： B82Y30/00 ,  A61K8/29 ,  A61K8/731 ,  A61K8/732 ,  A61K8/733 ,  A61K8/8147 ,  A61Q1/02 ,  A61Q17/04 ,  C01P2002/82 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2004/82 ,  C01P2004/86 ,  C01P2006/60 ,  C09C1/043 ,  C09C1/3661 ,  Y10S514/972

    摘要： A cosmetic composition comprising titanium oxide coated with one or both of silica and alumina or zinc oxide coated with one or both of silica and alumina, and a thickening polymer having a carboxyl group in the side chain, preferably a carboxyvinyl polymer, wherein when 10% by mass of silica- and/or alumina-coated titanium oxide or silica- and/or alumina-coated zinc oxide is dispersed in an aqueous solution containing 0.133% by mass of a carboxyvinyl polymer, the viscosity after the passing of 100 hours is 50% or more of the initial viscosity. A cosmetic composition comprising titanium oxide coated with one or both silica and alumina or zinc oxide coated with one or both of silica and alumina, and a thickening polymer having a carboxyl group in the side chain of the invention, can maintain emulsion stability by thickening of polymer for a long period of time and can be widely and suitably used for ultraviolet shielding cosmetic materials or the like having preparation form stability.

    摘要翻译： 一种化妆品组合物，其包含用二氧化硅和氧化铝中的一种或二者涂覆的二氧化钛或涂覆有二氧化硅和氧化铝中的一种或两种的氧化锌，以及在侧链中具有羧基的增稠聚合物，优选羧基乙烯基聚合物，其中当10％ 的二氧化硅和/或氧化铝涂覆的氧化钛或二氧化硅和/或氧化铝涂覆的氧化锌分散在含有0.133质量％羧基乙烯基聚合物的水溶液中，100小时后的粘度为50 ％以上的初始粘度。 包含二氧化硅和氧化铝或二氧化硅或二氧化硅和氧化铝中的一种或二者涂覆的二氧化钛的化妆品组合物和本发明侧链具有羧基的增稠聚合物可以通过增稠而保持乳液的稳定性 聚合物长时间并且可广泛适用于具有制备形式稳定性的紫外线屏蔽化妆品等。