Method for using glycol additives to texturally modify natural gum hydrogels
    8.
    发明授权
    Method for using glycol additives to texturally modify natural gum hydrogels 有权
    使用二醇添加剂来质地修饰天然胶水凝胶的方法

    公开(公告)号:US06664301B1

    公开(公告)日:2003-12-16

    申请号:US10079953

    申请日:2002-02-20

    申请人: Robert D. Kross

    发明人: Robert D. Kross

    IPC分类号: B01J1300

    摘要: A method for strengthening a hydrogel of a naturally-occurring gelling agent, or a derivative thereof, including the step of adding at least one glycol to the gelling agent of the general formula: HO—(CH2)n—OH, HO—(CH2—CH2O)x—H, HO—(CH2—CH2—CH2O)y—H; and, HO—(CH2—CH[CH3]—O)y—H, in which, n is from 2 to about 8; x is from 6 to about 30; and, y is from 4 to about 20. Also useful of those of the general structure: HO—[C(R1)(R2)—C(R3)(R4)]—OH, in which, R1, R2, R3, R4 are capable of being —H in all four positions, or H in 0, 1, 2, 3 positions and —CH3 or —C2H5 in any or all of the non-H occupied positions. Further, 1,2-propylene glycol and its ether derivatives, having only secondary alcohol groups, are particularly useful, having the general structure: R5O—CH2—CH(CH3)—OR6, in which, either or both R5 and R6 are H or —CH2—CH(OH)—CH3.

    摘要翻译: 一种强化天然胶凝剂或其衍生物的水凝胶的方法,包括将至少一种二醇加入到通式的胶凝剂中的步骤:其中n为2至约8; x为 从6到约30; 并且y为4至约20.对于一般结构的那些也是有用的:其中R 1,R 2,R 3,R 4在所有四个中都可以是-H 位置,或在任何或所有非H占据位置的0,1,2,3位和-CH 3或-C 2 H 5中的H。此外,仅具有仲醇基的1,2-丙二醇及其醚衍生物, 具有一般结构:其中,R 5和R 6中的任一个或两个是H或-CH 2 -CH(OH)-CH 3。

    Process and compositions
    9.
    发明授权
    Process and compositions 失效
    工艺和成分

    公开(公告)号:US4242328A

    公开(公告)日:1980-12-30

    申请号:US72206

    申请日:1979-09-04

    摘要: Dried amorphous aluminum hydroxide gels having substantial acid reacting capability over an extended period of time are prepared by drying the gel after contacting the aqueous liquid gel with an inert organic solvent of sufficient solubility in water to replace water in the gel. The dried gel product and pharmaceutical compositions comprising the gel are also novel.

    摘要翻译: 通过在水性液体凝胶与水中具有足够的溶解度的惰性有机溶剂接触来干燥凝胶后,通过干燥凝胶来制备干燥的无定形氢氧化铝凝胶,以在更长的时间内具有显着的酸反应能力,以取代凝胶中的水。 包含凝胶的干燥凝胶产品和药物组合物也是新颖的。