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    Nucleic acids encoding BDP-1
    1.
    发明授权
    Nucleic acids encoding BDP-1 失效
    编码BDP-1的核酸

    公开(公告)号：US07074589B1

    公开(公告)日：2006-07-11

    申请号：US08877150

    申请日：1997-06-17

    Applicant: Axel Ullrich ,  Naohito Aoki ,  Yeong Woong Kim ,  Hong Yang Wang ,  Zhengjun Chen ,  Oliver Nayler ,  Alexei Kharitonenkov

    Inventor： Axel Ullrich ,  Naohito Aoki ,  Yeong Woong Kim ,  Hong Yang Wang ,  Zhengjun Chen ,  Oliver Nayler ,  Alexei Kharitonenkov

    IPC: C12P21/06

    CPC classification number: C12N9/1205 ,  A61K38/00 ,  C07K14/4703 ,  C07K16/18 ,  C07K16/40 ,  C12N9/16

    Abstract: Nucleic acid molecules encoding full length PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptides, portions of such nucleic acid molecules, nucleic acid vectors containing such nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that bind such polypeptides or abrogate their interactions with natural binding partners. Methods for diagnosing abnormal conditions in an organism with PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP related molecules or compounds. PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, or SIRP polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for diseases related to PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptide or conditions characterized by an abnormal interaction between such a polypeptide and its binding partner.

    Abstract translation: 编码全长PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP多肽的核酸分子，这些核酸分子的部分，含有该核酸分子的核酸载体，含有该核酸载体的重组细胞，纯化的多肽 来自这样的重组细胞，对这些多肽的抗体，以及鉴定结合这些多肽的化合物或废除其与天然结合配偶体的相互作用的方法。 用于诊断具有PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP相关分子或化合物的生物体的异常状况的方法。 PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4或SIRP多肽，编码此类多肽的核酸，含有此类核酸的细胞，组织和动物，使用此类多肽的抗体，以及与所有这些多肽相关的方法 以上。 提供了与PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP多肽有关的疾病或特征为这种多肽与其结合配偶体之间异常相互作用的病症的治疗，诊断和筛选方法。

    Method for Expression and Accumulation of Peptide in Plant
    4.
    发明申请
    Method for Expression and Accumulation of Peptide in Plant 审中-公开
    植物中肽的表达和积累方法

    公开(公告)号：US20090249513A1

    公开(公告)日：2009-10-01

    申请号：US11885762

    申请日：2006-03-01

    Applicant: Tsukasa Matsuda ,  Naohito Aoki ,  Fujio Hashizume ,  Shingo Hino ,  Misako Kakehashi

    Inventor： Tsukasa Matsuda ,  Naohito Aoki ,  Fujio Hashizume ,  Shingo Hino ,  Misako Kakehashi

    IPC: A01H1/00 ,  C12N15/63 ,  A01H5/00

    CPC classification number: C12N15/8261 ,  C12N15/821 ,  Y02A40/146

    Abstract: The present invention relates to a method for expressing and accumulating a low-molecular peptide in plant seeds; a vector therefore; and a plant transformed with the vector. In the present invention, an intended peptide composed of 3 to 40 amino acid residues is expressed and accumulated in seeds of a plant by transforming the plant with a fusion protein expression vector comprising a gene encoding a member of the glutelin multigene family and two or more copies of a gene encoding the intended peptide ligated downstream of the gene under the control of a promoter.

    Abstract translation: 本发明涉及用于在植物种子中表达和积累低分子量肽的方法; 因此， 和用该载体转化的植物。 在本发明中，通过用包含编码谷蛋白多基因家族成员的基因和两个或更多个的融合蛋白质表达载体转化植物，将由3-40个氨基酸残基组成的预期肽表达并积累在植物的种子中 在启动子控制下编码在基因下游连接的预期肽的基因的拷贝。

    Novel PTP-20, PCP-2, BDP1, CLK, and SIRP proteins and related products and methods
    6.
    发明申请
    Novel PTP-20, PCP-2, BDP1, CLK, and SIRP proteins and related products and methods 审中-公开
    新型PTP-20，PCP-2，BDP1，CLK和SIRP蛋白及相关产品及方法

    公开(公告)号：US20080051556A1

    公开(公告)日：2008-02-28

    申请号：US11153918

    申请日：2005-06-16

    Applicant: Axel Ullrich ,  Naohito Aoki ,  Yeong Woong Kim ,  Hong Yang Wang ,  Zhengjun Chen ,  Oliver Nayler ,  Alexei Kharitonenkov

    Inventor： Axel Ullrich ,  Naohito Aoki ,  Yeong Woong Kim ,  Hong Yang Wang ,  Zhengjun Chen ,  Oliver Nayler ,  Alexei Kharitonenkov

    IPC: C07K2/00 ,  C07H21/00 ,  C07K16/00

    CPC classification number: C12N9/1205 ,  A61K38/00 ,  C07K14/4703 ,  C07K16/18 ,  C07K16/40 ,  C12N9/16

    Abstract: Nucleic acid molecules encoding full length PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptides, portions of such nucleic acid molecules, nucleic acid vectors containing such nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that bind such polypeptides or abrogate their interactions with natural binding partners. Methods for diagnosing abnormal conditions in an organism with PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP related molecules or compounds. PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, or SIRP polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for diseases related to PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptides or conditions characterized by an abnormal interaction between such a polypeptide and its binding partner.

    Abstract translation: 编码全长PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP多肽的核酸分子，这些核酸分子的部分，含有该核酸分子的核酸载体，含有该核酸载体的重组细胞，纯化的多肽 来自这样的重组细胞，对这些多肽的抗体，以及鉴定结合这些多肽的化合物或废除其与天然结合配偶体的相互作用的方法。 用于诊断具有PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP相关分子或化合物的生物体的异常状况的方法。 PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4或SIRP多肽，编码此类多肽的核酸，含有此类核酸的细胞，组织和动物，使用此类多肽的抗体，以及与所有这些多肽相关的方法 以上。 为与PTP20，PCP-2，BDP1，mCLK2，mCLK3，mCLK4和SIRP多肽相关的疾病或特征为这种多肽与其结合配偶体之间的异常相互作用的病症提供了治疗，诊断和筛选方法。

    Protein tyrosine phosphatase PTP20 and related products and methods
    9.
    发明授权
    Protein tyrosine phosphatase PTP20 and related products and methods 失效
    蛋白酪氨酸磷酸酶PTP20及相关产品及方法

    公开(公告)号：US06482605B1

    公开(公告)日：2002-11-19

    申请号：US09430626

    申请日：1999-10-29

    Applicant: Naohito Aoki ,  Axel Ullrich

    Inventor： Naohito Aoki ,  Axel Ullrich

    IPC: C12Q142

    CPC classification number: C12N9/1205 ,  A61K38/00 ,  C07K14/4703 ,  C07K16/18 ,  C07K16/40 ,  C12N9/16

    Abstract: The present invention relates to a novel polypeptide, PTP20, and to nucleic acid molecules encoding the polypeptide . The invention also relates to nucleic acid molecules encoding portions of the phosphatase, nucleic acid vectors containing PTP20 related nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that bind PTP20 or abrogate its interactions with natural binding partners. Also disclosed are methods for diagnosing abnormal conditions in an organism with PTP20 related molecules or compounds.

    Abstract translation: 本发明涉及新型多肽PTP20，以及编码该多肽的核酸分子。 本发明还涉及编码部分磷酸酶的核酸分子，含有PTP20相关核酸分子的核酸载体，含有此类核酸载体的重组细胞，从这些重组细胞纯化的多肽，对这些多肽的抗体，以及鉴定化合物的方法 结合PTP20或废除其与天然结合配偶体的相互作用。 还公开了用PTP20相关分子或化合物诊断生物体中的异常状况的方法。

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