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    Calibration method for the prospective calibration of measuring equipment
    1.
    发明授权
    Calibration method for the prospective calibration of measuring equipment 有权
    测量设备预期校准的校准方法

    公开(公告)号：US09222951B2

    公开(公告)日：2015-12-29

    申请号：US13405815

    申请日：2012-02-27

    申请人： Nikolaus Schmitt ,  Gerhard Frisch

    发明人： Nikolaus Schmitt ,  Gerhard Frisch

    IPC分类号： A61B5/00 ,  G01N35/00 ,  A61B5/145 ,  A61B5/1495 ,  G01N27/327

    CPC分类号： G06F17/18 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7207 ,  A61B5/7232 ,  A61B2560/0223 ,  G01N27/3271 ,  G01N33/66 ,  G01N35/00693 ,  G01N2035/00702

    摘要： A method for operating measuring equipment for detecting an analyte in a bodily fluid by means of a continuously measuring blood glucose sensor. A calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises a measurement signal from the measuring equipment and a reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method using a formation of at least one median is used to determine a probable slope from the plurality of possible slopes. Furthermore, a measurement is carried out. During the measurement and using the probable slope, a concentration of the analyte in the bodily fluid is deduced from a measurement signal from the measuring equipment and the probable slope.

    摘要翻译： 一种用于通过连续测量血糖传感器检测体液中分析物的测量设备的方法。 对测量设备的预期校准进行校准方法。 在校准方法中至少检测到三个校准点，其中每个校准点包括来自测量设备的测量信号和相关参考测量的参考值。 在校准点之间建立多个可能的斜率。 使用至少一个中值的形成的至少一个鲁棒估计方法用于确定来自多个可能斜率的可能的斜率。 此外，进行测量。 在测量和使用可能的斜率时，从测量设备的测量信号和可能的斜率推断出体液中分析物的浓度。

    Direct detection Doppler LIDAR method and direction detection Doppler LIDAR device
    3.
    发明授权
    Direct detection Doppler LIDAR method and direction detection Doppler LIDAR device 有权
    直接检测多普勒LIDAR方法和方向检测多普勒激光雷达装置

    公开(公告)号：US08675184B2

    公开(公告)日：2014-03-18

    申请号：US13002483

    申请日：2009-06-30

    申请人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    发明人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    IPC分类号： G01P3/36

    CPC分类号： G01S17/95 ,  Y02A90/19

    摘要： The invention relates to a method for Doppler light detection and ranging (LIDAR) measurement of speeds. A laser beam is directed at the medium to be measured, and radiation which is then emitted by the medium is measured by a detector. In order to allow better control of the dynamic range of a direct reception Doppler LIDAR apparatus, a multiplicity of laser pulses can be transmitted per measurement, and a multiplicity of laser pulses can be received by the detector per measurement. A direct reception Doppler LIDAR apparatus can be suitable for carrying out the method.

    摘要翻译： 本发明涉及用于多普勒光检测和测距（LIDAR）速度测量的方法。 激光束被引导到要测量的介质上，然后通过检测器测量由介质发射的辐射。 为了更好地控制直接接收多普勒激光雷达装置的动态范围，可以每次测量发送多个激光脉冲，并且每次测量可以由检测器接收多个激光脉冲。 直接接收多普勒激光雷达装置可以适用于执行该方法。

    Calibration of a handheld diabetes managing device that receives data from a continuous glucose monitor
    4.
    发明授权
    Calibration of a handheld diabetes managing device that receives data from a continuous glucose monitor 有权
    从连续葡萄糖监测器接收数据的手持式糖尿病管理装置的校准

    公开(公告)号：US08589106B2

    公开(公告)日：2013-11-19

    申请号：US12975769

    申请日：2010-12-22

    申请人： Timothy Peter Engelhardt ,  Nikolaus Schmitt ,  Phillip E. Pash ,  David Duke ,  Abhishek Soni

    发明人： Timothy Peter Engelhardt ,  Nikolaus Schmitt ,  Phillip E. Pash ,  David Duke ,  Abhishek Soni

    IPC分类号： G01C19/00 ,  G01C25/00 ,  G01D18/00 ,  G01F25/00 ,  G06F19/00 ,  A61B5/05 ,  A61B5/00

    CPC分类号： A61B5/14532 ,  G06F19/00 ,  G16H40/40

    摘要： A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.

    摘要翻译： 一种用于基于由连续葡萄糖监测器生成的数据来校准手持式糖尿病管理装置的方法。 该方法可以包括在一段时间内以采样间隔对连续葡萄糖监测器的电流进行采样，以在该时间段内产生多个当前采样。 该方法还可以包括确定多个当前样本的平均值，中值和标准偏差。 可以在第一时间测量患者的血糖水平，并且可以基于测量的血糖水平和多个当前样本将多个当前样本与患者的估计葡萄糖水平相关联的校准方程可以在 标准偏差小于第一阈值，平均值和中值之间的差的绝对值小于第二阈值。

    CALIBRATION METHOD FOR THE PROSPECTIVE CALIBRATION OF MEASURING EQUIPMENT
    5.
    发明申请
    CALIBRATION METHOD FOR THE PROSPECTIVE CALIBRATION OF MEASURING EQUIPMENT 有权
    用于测量设备的前瞻性校准的校准方法

    公开(公告)号：US20120191362A1

    公开(公告)日：2012-07-26

    申请号：US13405815

    申请日：2012-02-27

    申请人： Nikolaus Schmitt ,  Gerhard Frisch

    发明人： Nikolaus Schmitt ,  Gerhard Frisch

    IPC分类号： G06F17/18 ,  G01N33/66

    CPC分类号： G06F17/18 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7207 ,  A61B5/7232 ,  A61B2560/0223 ,  G01N27/3271 ,  G01N33/66 ,  G01N35/00693 ,  G01N2035/00702

    摘要： A method for operating measuring equipment for detecting an analyte in a bodily fluid by means of a continuously measuring blood glucose sensor. A calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises a measurement signal from the measuring equipment and a reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method, using a formation of at least one median is used to determine a probable slope from the plurality of possible slopes. Furthermore, a measurement is carried out. During the measurement and using the probable slope, a concentration of the analyte in the bodily fluid is deduced from a measurement signal from the measuring equipment and the probable slope.

    摘要翻译： 一种用于通过连续测量血糖传感器检测体液中分析物的测量设备的方法。 对测量设备的预期校准进行校准方法。 在校准方法中至少检测到三个校准点，其中每个校准点包括来自测量设备的测量信号和相关参考测量的参考值。 在校准点之间建立多个可能的斜率。 使用至少一个中值的形成的至少一个鲁棒估计方法用于从多个可能的斜率确定可能的斜率。 此外，进行测量。 在测量和使用可能的斜率时，从测量设备的测量信号和可能的斜率推断出体液中分析物的浓度。

    CALIBRATION OF A HANDHELD DIABETES MANAGING DEVICE THAT RECEIVES DATA FROM A CONTINUOUS GLUCOSE MONITOR
    6.
    发明申请
    CALIBRATION OF A HANDHELD DIABETES MANAGING DEVICE THAT RECEIVES DATA FROM A CONTINUOUS GLUCOSE MONITOR 有权
    手持式糖尿病管理装置的校准从连续葡萄糖监测器接收数据

    公开(公告)号：US20120166126A1

    公开(公告)日：2012-06-28

    申请号：US12975769

    申请日：2010-12-22

    申请人： Timothy Peter Engelhardt ,  Nikolaus Schmitt ,  Phillip E. Pash ,  David Duke ,  Abhishek Soni

    发明人： Timothy Peter Engelhardt ,  Nikolaus Schmitt ,  Phillip E. Pash ,  David Duke ,  Abhishek Soni

    IPC分类号： G06F19/00

    CPC分类号： A61B5/14532 ,  G06F19/00 ,  G16H40/40

    摘要： A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.

    摘要翻译： 一种用于基于由连续葡萄糖监测器生成的数据来校准手持式糖尿病管理装置的方法。 该方法可以包括在一段时间内以采样间隔对连续葡萄糖监测器的电流进行采样，以在该时间段内产生多个当前采样。 该方法还可以包括确定多个当前样本的平均值，中值和标准偏差。 可以在第一时间测量患者的血糖水平，并且可以基于测量的血糖水平和多个当前样本将多个当前样本与患者的估计葡萄糖水平相关联的校准方程可以在 标准偏差小于第一阈值，平均值和中值之间的差的绝对值小于第二阈值。

    LIDAR METHOD FOR MEASURING SPEEDS AND LIDAR DEVICE WITH TIME-CONTROLLED DETECTION
    7.
    发明申请
    LIDAR METHOD FOR MEASURING SPEEDS AND LIDAR DEVICE WITH TIME-CONTROLLED DETECTION 有权
    用于测量速度和激光装置的激光雷达方法，具有时间控制检测

    公开(公告)号：US20110181864A1

    公开(公告)日：2011-07-28

    申请号：US13002479

    申请日：2009-06-30

    申请人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    发明人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    IPC分类号： G01P3/36

    CPC分类号： G01S17/95 ,  G01S17/58 ,  Y02A90/19

    摘要： The invention relates to a method for light detecting and ranging (LIDAR) measurement of speeds, in which a laser beam is directed at the medium to be measured, and radiation which is subsequently emitted from the medium (16) is measured by a detector. In order to optimize the measurement, a spatial measurement range can be selected by activation and/or deactivation of the detector for at least one predetermined or regulated time duration of less than about 500 μs after emission of a laser pulse to the medium to be measured. Furthermore, a direct reception Doppler LIDAR apparatus can be used to perform the method.

    摘要翻译： 本发明涉及一种用于光检测和测距（LIDAR）测量速度的方法，其中激光束被引导到要测量的介质，并且随后从介质（16）发射的辐射由检测器测量。 为了优化测量，可以通过激活和/或去激活检测器来选择空间测量范围，以便在向待测介质发射激光脉冲之后的小于约500μs的至少一个预定或调节的持续时间内 。 此外，可以使用直接接收多普勒激光雷达装置来执行该方法。

    LIDAR method for measuring speeds and LIDAR device with time-controlled detection
    10.
    发明授权
    LIDAR method for measuring speeds and LIDAR device with time-controlled detection 有权
    用于测量速度的LIDAR方法和具有时间控制检测的激光雷达装置

    公开(公告)号：US09383447B2

    公开(公告)日：2016-07-05

    申请号：US13002479

    申请日：2009-06-30

    申请人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    发明人： Nikolaus Schmitt ,  Wolfgang Rehm ,  Thomas Pistner

    IPC分类号： G01P3/36 ,  G01S17/95 ,  G01S17/58

    CPC分类号： G01S17/95 ,  G01S17/58 ,  Y02A90/19

    摘要： The invention relates to a method for light detecting and ranging (LIDAR) measurement of speeds, in which a laser beam is directed at the medium to be measured, and radiation which is subsequently emitted from the medium (16) is measured by a detector. In order to optimize the measurement, a spatial measurement range can be selected by activation and/or deactivation of the detector for at least one predetermined or regulated time duration of less than about 500 μs after emission of a laser pulse to the medium to be measured. Furthermore, a direct reception Doppler LIDAR apparatus can be used to perform the method.

    摘要翻译： 本发明涉及一种用于光检测和测距（LIDAR）测量速度的方法，其中激光束被引导到要测量的介质，并且随后从介质（16）发射的辐射由检测器测量。 为了优化测量，可以通过激活和/或去激活检测器来选择空间测量范围，以便在向待测介质发射激光脉冲之后的小于约500μs的至少一个预定或调节的持续时间内 。 此外，可以使用直接接收多普勒激光雷达装置来执行该方法。