公开(公告)号：US20180148680A1

公开(公告)日：2018-05-31

申请号：US15574530

申请日：2016-05-24

申请人： Norihisa SASAYAMA ,  Masakatsu TAKEUCHI ,  Atsushi TAGUCHI ,  Nipro Corporation

发明人： Norihisa Sasayama ,  Masakatsu Takeuchi ,  Atsushi Taguchi

IPC分类号： C12M1/00 ,  B01D63/16 ,  B01D63/04 ,  C12M1/36

CPC分类号： C12M47/02 ,  B01D61/243 ,  B01D63/02 ,  B01D63/04 ,  B01D63/16 ,  B01D2313/06 ,  B01D2313/10 ,  B01D2313/12 ,  B01D2315/02 ,  B01D2315/18 ,  C12M1/10 ,  C12M3/02 ,  C12M3/043 ,  C12M3/06 ,  C12M3/065 ,  C12M23/14 ,  C12M23/42 ,  C12M23/44 ,  C12M23/50 ,  C12M29/04 ,  C12M29/16 ,  C12M41/48

摘要： A means capable of simply and efficiently concentrating a cell suspension. A concentrator has a culture vessel having a first port and a second port, a server bag having a port, a case having a hollow fiber bundle in the internal space, a filtering device having an inlet port, a first outlet port, and a second outlet port, a collection vessel having a port, a liquid supply circuit connected to the first port, the inlet port, and the server bag's port so that flow passages are switchable, a liquid discharge circuit connected to the second port, the first outlet port, the second outlet port, and the collection vessel's port so that flow passages are switchable, a liquid supply mechanism having a switching mechanism, a supply pump, and a discharge pump, and a rotation mechanism rotating the filtering device.

公开(公告)号：US6129853A

公开(公告)日：2000-10-10

申请号：US196760

申请日：1998-11-20

申请人： Norihisa Sasayama ,  Toshihiro Kikuchi ,  Shinichiro Harada ,  Nobuo Takagi ,  Takahito Wakabayashi

发明人： Norihisa Sasayama ,  Toshihiro Kikuchi ,  Shinichiro Harada ,  Nobuo Takagi ,  Takahito Wakabayashi

IPC分类号： A61M1/36 ,  B01D37/00 ,  A61M5/165

CPC分类号： A61M1/3633 ,  A61M1/3636 ,  A61M2202/0439

摘要： A filter set for recovering desired blood components from human blood and a method for recovering blood components using the filter set are provided. The filter set includes a bag body and an accommodation vessel for accommodating the bag body therein in a compressed condition. In the method the bag body is provided in the accommodation vessel and is compressed and blood is passed through the compressed bag body. Blood components are adhered to the compressed filter material in the bag body. Thereafter, the compression of the bag body is relieved and a washing solution is passed through the expanded bag body to remove the blood components contained therein.

摘要翻译： 提供了一种用于从人血中回收所需血液成分的过滤器组和使用该过滤器组来回收血液成分的方法。 过滤器组包括袋体和用于在压缩状态下容纳袋体的容纳容器。 在该方法中，将袋体设置在容纳容器中并被压缩，血液通过压缩袋体。 血液成分粘附在袋体内的压缩过滤材料上。 此后，释放袋体的压缩，使洗涤液通过膨胀袋体，除去其中所含的血液成分。

公开(公告)号：US10793822B2

公开(公告)日：2020-10-06

申请号：US15574530

申请日：2016-05-24

申请人： Nipro Corporation ,  Norihisa Sasayama ,  Masakatsu Takeuchi ,  Atsushi Taguchi

发明人： Norihisa Sasayama ,  Masakatsu Takeuchi ,  Atsushi Taguchi

IPC分类号： C12M1/00 ,  C12M1/10 ,  C12M3/06 ,  C12M3/00 ,  B01D63/02 ,  C12M3/04 ,  C12M3/02 ,  B01D63/04 ,  B01D63/16 ,  C12M1/36 ,  B01D61/24

摘要： A means capable of simply and efficiently concentrating a cell suspension. A concentrator has a culture vessel having a first port and a second port, a server bag having a port, a case having a hollow fiber bundle in the internal space, a filtering device having an inlet port, a first outlet port, and a second outlet port, a collection vessel having a port, a liquid supply circuit connected to the first port, the inlet port, and the server bag's port so that flow passages are switchable, a liquid discharge circuit connected to the second port, the first outlet port, the second outlet port, and the collection vessel's port so that flow passages are switchable, a liquid supply mechanism having a switching mechanism, a supply pump, and a discharge pump, and a rotation mechanism rotating the filtering device.

公开(公告)号：US09050403B2

公开(公告)日：2015-06-09

申请号：US12311533

申请日：2007-10-19

申请人： Shinji Morimoto ,  Norihisa Sasayama ,  Akio Shirasu

发明人： Shinji Morimoto ,  Norihisa Sasayama ,  Akio Shirasu

IPC分类号： B01D29/00 ,  A61M1/02 ,  A61B5/15 ,  A61K35/16 ,  A61M5/315 ,  A61M5/31

CPC分类号： A61M1/029 ,  A61B5/1416 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150335 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/1535 ,  A61K35/16 ,  A61M5/31511 ,  A61M2005/3104 ,  A61M2005/3106 ,  A61M2005/31598 ,  A61M2202/0427

摘要： Provided is a platelet-rich plasma separator which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe and a second syringe. The first syringe comprises a first syringe cylinder provided with a first port on which a blood collection needle can be mounted, a first cap detachable from the first port, a first gasket for sealing the first syringe cylinder fluid-tightly, which first gasket is reciprocated within the first syringe cylinder, and a first plunger provided detachably on the first gasket. The second syringe comprises a first hollow needle, which can be passed through the first gasket, a second syringe cylinder having a second port on which the first hollow needle can be mounted, a second cap detachable from the second port, a second gasket for sealing the second syringe cylinder liquid-tightly, which second gasket is reciprocated within the second syringe cylinder, and a second plunger provided detachable on the second gasket.

摘要翻译： 提供了一种富含血小板的血浆分离器，其可以用少量的γ射线灭菌器械和富含血小板的血浆分离方法进行富血小板血浆的分离。 富含血小板的血浆分离器包括第一注射器和第二注射器。 第一注射器包括：第一注射器筒，其设置有可以安装采血针的第一端口;可从第一端口拆卸的第一帽;用于密封第一注射器筒的第一垫圈，第一垫圈往复运动 在第一注射器筒内，以及可拆卸地设置在第一垫圈上的第一柱塞。 第二注射器包括可以穿过第一垫片的第一中空针，具有可以安装第一中空针的第二端口的第二注射器筒，可从第二端口拆卸的第二帽，用于密封的第二垫圈 所述第二注射器筒液体密封，所述第二垫圈在所述第二注射器筒内往复运动，以及第二柱塞，其设置在所述第二垫圈上。

公开(公告)号：US20100025342A1

公开(公告)日：2010-02-04

申请号：US12311533

申请日：2009-04-02

申请人： Shinji Morimoto ,  Norihisa Sasayama ,  Akio Shirasu

发明人： Shinji Morimoto ,  Norihisa Sasayama ,  Akio Shirasu

IPC分类号： B01D21/26

CPC分类号： A61M1/029 ,  A61B5/1416 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150335 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/1535 ,  A61K35/16 ,  A61M5/31511 ,  A61M2005/3104 ,  A61M2005/3106 ,  A61M2005/31598 ,  A61M2202/0427

摘要： Provided is a platelet-rich plasma separator which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe and a second syringe. The first syringe comprises a first syringe cylinder provided with a first port on which a blood collection needle can be mounted, a first cap detachable from the first port, a first gasket for sealing the first syringe cylinder fluid-tightly, which first gasket is reciprocated within the first syringe cylinder, and a first plunger provided detachably on the first gasket. The second syringe comprises a first hollow needle, which can be passed through the first gasket, a second syringe cylinder having a second port on which the first hollow needle can be mounted, a second cap detachable from the second port, a second gasket for sealing the second syringe cylinder liquid-tightly, which second gasket is reciprocated within the second syringe cylinder, and a second plunger provided detachable on the second gasket.

摘要翻译： 提供了一种富含血小板的血浆分离器，其可以用少量的γ射线灭菌器械和富含血小板的血浆分离方法进行富血小板血浆的分离。 富含血小板的血浆分离器包括第一注射器和第二注射器。 第一注射器包括：第一注射器筒，其设置有可以安装采血针的第一端口;可从第一端口拆卸的第一帽;用于密封第一注射器筒的第一垫圈，第一垫圈往复运动 在第一注射器筒内，以及可拆卸地设置在第一垫圈上的第一柱塞。 第二注射器包括可以穿过第一垫圈的第一中空针，具有可以安装第一中空针的第二端口的第二注射器筒，可从第二端口拆卸的第二帽，用于密封的第二垫圈 所述第二注射器筒液体密封，所述第二垫圈在所述第二注射器筒内往复运动，以及第二柱塞，其设置在所述第二垫圈上。