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公开(公告)号:US20090042264A1
公开(公告)日:2009-02-12
申请号:US12195869
申请日:2008-08-21
摘要: Nucleotide sequences and genetic constructs that can be used to regulate genes encoding enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also are provided.
摘要翻译: 提供了可用于调节编码通过代谢途径转化碳通量的基因的基因组序列和遗传构建体,所述代谢途径导致宿主细胞例如米曲霉细胞中的乳酸或富马酸盐的产生。 还提供了操作细胞中碳通量的方法。
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公开(公告)号:US07838278B2
公开(公告)日:2010-11-23
申请号:US12409072
申请日:2009-03-23
IPC分类号: C12N1/20 , C12N1/00 , C12N15/74 , C12N15/76 , C12N15/77 , C12N15/00 , C12N9/00 , C12N9/10 , C12P19/34 , C12P21/06 , C07H21/04
CPC分类号: C12P7/46 , C12N9/93 , C12P7/20 , C12P7/56 , C12Y604/01001
摘要: Nucleotide and protein sequences that encode enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also are provided.
摘要翻译: 提供编码通过代谢途径改变碳通量的酶的核苷酸和蛋白质序列,其导致宿主细胞如米曲霉细胞中的乳酸或富马酸盐的产生。 还提供了操作细胞中碳通量的方法。
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公开(公告)号:US07566563B2
公开(公告)日:2009-07-28
申请号:US12195869
申请日:2008-08-21
摘要: Nucleotide sequences and genetic constructs that can be used to regulate genes encoding enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also are provided.
摘要翻译: 提供了可用于调节编码通过代谢途径转化碳通量的基因的基因组序列和遗传构建体,所述代谢途径导致宿主细胞例如米曲霉细胞中的乳酸或富马酸盐的产生。 还提供了操作细胞中碳通量的方法。
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公开(公告)号:US20100112651A1
公开(公告)日:2010-05-06
申请号:US12409072
申请日:2009-03-23
IPC分类号: C12P7/56 , C07H21/00 , C07H21/02 , C12N15/74 , C12N1/21 , C12N1/19 , C12N1/15 , C12P7/46 , C12P7/20
CPC分类号: C12P7/46 , C12N9/93 , C12P7/20 , C12P7/56 , C12Y604/01001
摘要: Nucleotide and protein sequences that encode enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also are provided.
摘要翻译: 提供编码通过代谢途径改变碳通量的酶的核苷酸和蛋白质序列,其导致宿主细胞如米曲霉细胞中的乳酸或富马酸盐的产生。 还提供了操作细胞中碳通量的方法。
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公开(公告)号:US07435168B2
公开(公告)日:2008-10-14
申请号:US11334713
申请日:2006-01-17
摘要: Nucleotide sequences and genetic constructs that can be used to regulate genes encoding enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also are provided.
摘要翻译: 提供了可用于调节编码通过代谢途径转化碳通量的基因的基因组序列和遗传构建体,所述代谢途径导致宿主细胞例如米曲霉细胞中的乳酸或富马酸盐的产生。 还提供了操作细胞中碳通量的方法。
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